eigengene (Q113330977)

From Wikidata
Jump to navigation Jump to search
one of a set of right singular vectors of a genes x samples matrix that tabulates, e.g., the mRNA or gene expression of the genes across the samples
edit
Language Label Description Also known as
English
eigengene
one of a set of right singular vectors of a genes x samples matrix that tabulates, e.g., the mRNA or gene expression of the genes across the samples

    Statements

    0 references
    0 references
    0 references
    0 references
    0 references
    2 references
    September 2015
    Dr. Orly Alter
    Dr. Orly Alter is a USTAR associate professor of bioengineering and human genetics at the Scientific Computing and Imaging Institute and the Huntsman Cancer Institute at the University of Utah. Inventor of the "eigengene," she pioneered the matrix and tensor modeling of large-scale molecular biological data, which, as she demonstrated, can be used to correctly predict previously unknown cellular mechanisms. (English)
    1990s
    2 references
    1999, Orly Alter et al., ‘‘Singular Value Decomposition for Gene Expression Data Processing and Modeling.’’ In: After the Genome V (December 6–10, 1999, Jackson Hole, WY) (English)
    We describe the use of singular value decomposition in transforming gene expression data from genes/arrays space to ‘‘eigengenes’’/‘‘eigenarrays’’ space, where the eigengenes and eigenarrays are unique orthonormal superpositions of the genes and arrays, respectively. (English)
    Alter Lab (English)
    We describe the use of singular value decomposition in transforming gene expression data from genes/arrays space to ‘‘eigengenes’’/‘‘eigenarrays’’ space, where the eigengenes and eigenarrays are unique orthonormal superpositions of the genes and arrays, respectively. (English)
     
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                    edit