3-hydroxy-3-methylglutaryl-CoA lyase (Q21118307)

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mammalian protein found in Homo sapiens
  • HMG-CoA lyase
  • HMGCL
  • hydroxymethylglutaricaciduria
  • hydroxymethylglutaryl-CoA lyase, mitochondrial
  • mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase
  • 3-hydroxymethyl-3-methylglutaryl-CoA lyase
  • 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase
  • 3-hydroxy-3-methylglutarate-CoA lyase
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Language Label Description Also known as
English
3-hydroxy-3-methylglutaryl-CoA lyase
mammalian protein found in Homo sapiens
  • HMG-CoA lyase
  • HMGCL
  • hydroxymethylglutaricaciduria
  • hydroxymethylglutaryl-CoA lyase, mitochondrial
  • mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase
  • 3-hydroxymethyl-3-methylglutaryl-CoA lyase
  • 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase
  • 3-hydroxy-3-methylglutarate-CoA lyase

Statements

molecular function
hydroxymethylglutaryl-CoA lyase activity
determination method
IDA
IEA
TAS
10 references
retrieved
24 April 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
TAS
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
IEA
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
IEA
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
IEA
retrieved
24 April 2018
stated in
Identification and characterization of an extramitochondrial human 3-hydroxy-3-methylglutaryl-CoA lyase
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
24 April 2018
stated in
Characterization of a novel HMG-CoA lyase enzyme with a dual location in endoplasmic reticulum and cytosol
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
24 April 2018
stated in
Characterization of the hydroxymethylglutaryl-CoA lyase precursor, a protein targeted to peroxisomes and mitochondria
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
24 April 2018
stated in
Evidence supporting a role for histidine-235 in cation binding to human 3-hydroxy-3-methyglutaryl-CoA lyase
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
24 April 2018
stated in
3-Hydroxy-3-methylglutaryl coenzyme A lyase: targeting and processing in peroxisomes and mitochondria
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
24 April 2018
stated in
3-Hydroxy-3-methylglutaryl-CoA lyase: expression and isolation of the recombinant human enzyme and investigation of a mechanism for regulation of enzyme activity
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
IDA
hydroxymethylglutaryl-CoA lyase activity
determination method
IBA
IDA
IEA
TAS
11 references
retrieved
10 September 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
TAS
retrieved
10 September 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
IEA
retrieved
10 September 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
IEA
retrieved
10 September 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
IEA
retrieved
10 September 2018
stated in
Characterization of a novel HMG-CoA lyase enzyme with a dual location in endoplasmic reticulum and cytosol
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
10 September 2018
stated in
Evidence supporting a role for histidine-235 in cation binding to human 3-hydroxy-3-methyglutaryl-CoA lyase
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
10 September 2018
stated in
Characterization of the hydroxymethylglutaryl-CoA lyase precursor, a protein targeted to peroxisomes and mitochondria
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
10 September 2018
stated in
3-Hydroxy-3-methylglutaryl coenzyme A lyase: targeting and processing in peroxisomes and mitochondria
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
10 September 2018
stated in
Identification and characterization of an extramitochondrial human 3-hydroxy-3-methylglutaryl-CoA lyase
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
10 September 2018
stated in
3-Hydroxy-3-methylglutaryl-CoA lyase: expression and isolation of the recombinant human enzyme and investigation of a mechanism for regulation of enzyme activity
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35914&geneProductId=UniProtKB:P35914
determination method
IBA
hydroxymethylglutaryl-CoA lyase activity
determination method
IBA
IDA
IEA
10 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35914
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35914
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35914
determination method
IEA
retrieved
8 April 2019
stated in
Identification and characterization of an extramitochondrial human 3-hydroxy-3-methylglutaryl-CoA lyase
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
8 April 2019
stated in
3-Hydroxy-3-methylglutaryl coenzyme A lyase: targeting and processing in peroxisomes and mitochondria
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
8 April 2019
stated in
Evidence supporting a role for histidine-235 in cation binding to human 3-hydroxy-3-methyglutaryl-CoA lyase
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
8 April 2019
stated in
Characterization of a novel HMG-CoA lyase enzyme with a dual location in endoplasmic reticulum and cytosol
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
8 April 2019
stated in
Characterization of the hydroxymethylglutaryl-CoA lyase precursor, a protein targeted to peroxisomes and mitochondria
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
8 April 2019
stated in
3-Hydroxy-3-methylglutaryl-CoA lyase: expression and isolation of the recombinant human enzyme and investigation of a mechanism for regulation of enzyme activity
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35914
determination method
IBA
cell component
biological process
ketone body biosynthetic process
determination method
IBA
IDA
IEA
TAS
6 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35914
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35914
determination method
IEA
retrieved
8 April 2019
stated in
Evidence supporting a role for histidine-235 in cation binding to human 3-hydroxy-3-methyglutaryl-CoA lyase
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
8 April 2019
stated in
Identification and characterization of an extramitochondrial human 3-hydroxy-3-methylglutaryl-CoA lyase
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
8 April 2019
stated in
Characterization of a novel HMG-CoA lyase enzyme with a dual location in endoplasmic reticulum and cytosol
GOA
curator
UniProt
UniProt protein ID
P35914
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35914
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35914
determination method
IBA

Identifiers

 
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21118307&oldid=2022973244"