Ribonucleotide reductase catalytic subunit M1 &#160; ingelesa (Q21121233)

UniProt ^ingelesa

13 azaroa 2019

UniProt protein ID ^ingelesa

Erreferentzia bat

UniProt ^ingelesa

13 azaroa 2019

UniProt protein ID ^ingelesa

encoded by ^ingelesa

RRM1 ^ingelesa

Erreferentzia bat

UniProt ^ingelesa

13 azaroa 2019

UniProt protein ID ^ingelesa

funtzio molekular

nucleotide binding ^ingelesa

IEA ^ingelesa

Erreferentzia bat

8 apirila 2019

GOA ^ingelesa

UniProt ^ingelesa

UniProt protein ID ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

catalytic activity ^ingelesa

IEA ^ingelesa

Erreferentzia bat

8 apirila 2019

GOA ^ingelesa

UniProt ^ingelesa

UniProt protein ID ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

oxidoreductase activity ^ingelesa

IEA ^ingelesa

Erreferentzia bat

8 apirila 2019

GOA ^ingelesa

UniProt ^ingelesa

UniProt protein ID ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

ATP binding ^ingelesa

IEA ^ingelesa

2 erreferentzia

8 apirila 2019

GOA ^ingelesa

UniProt ^ingelesa

UniProt protein ID ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

8 apirila 2019

GOA ^ingelesa

InterPro ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

proteina lotura

IPI ^ingelesa

3 erreferentzia

8 apirila 2019

Enhanced subunit interactions with gemcitabine-5'-diphosphate inhibit ribonucleotide reductases. ^ingelesa

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IPI ^ingelesa

8 apirila 2019

Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization ^ingelesa

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IPI ^ingelesa

8 apirila 2019

Cyclin F-mediated degradation of ribonucleotide reductase M2 controls genome integrity and DNA repair ^ingelesa

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IPI ^ingelesa

ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor ^ingelesa

IEA ^ingelesa

ISS ^ingelesa

4 erreferentzia

24 apirila 2018

GOA ^ingelesa

UniProt ^ingelesa

UniProt protein ID ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23921&geneProductId=UniProtKB:P23921

ISS ^ingelesa

24 apirila 2018

GOA ^ingelesa

UniProt ^ingelesa

UniProt protein ID ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23921&geneProductId=UniProtKB:P23921

IEA ^ingelesa

24 apirila 2018

GOA ^ingelesa

InterPro ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23921&geneProductId=UniProtKB:P23921

IEA ^ingelesa

24 apirila 2018

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23921&geneProductId=UniProtKB:P23921

IEA ^ingelesa

identical protein binding ^ingelesa

IPI ^ingelesa

3 erreferentzia

8 apirila 2019

A proteome-scale map of the human interactome network ^ingelesa

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IPI ^ingelesa

8 apirila 2019

Enhanced subunit interactions with gemcitabine-5'-diphosphate inhibit ribonucleotide reductases. ^ingelesa

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IPI ^ingelesa

8 apirila 2019

Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization ^ingelesa

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IPI ^ingelesa

purine nucleotide binding ^ingelesa

IEA ^ingelesa

Erreferentzia bat

8 apirila 2019

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

disordered domain specific binding ^ingelesa

IEA ^ingelesa

Erreferentzia bat

8 apirila 2019

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor ^ingelesa

IBA ^ingelesa

IEA ^ingelesa

ISS ^ingelesa

5 erreferentzia

8 apirila 2019

GOA ^ingelesa

UniProt ^ingelesa

UniProt protein ID ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

ISS ^ingelesa

8 apirila 2019

GOA ^ingelesa

UniProt ^ingelesa

UniProt protein ID ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

8 apirila 2019

GOA ^ingelesa

InterPro ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

8 apirila 2019

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

8 apirila 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium ^ingelesa

GOA ^ingelesa

GO Central ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IBA ^ingelesa

cell component ^ingelesa

zitoplasma

IEA ^ingelesa

2 erreferentzia

8 apirila 2019

GOA ^ingelesa

UniProt ^ingelesa

UniProt protein ID ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

8 apirila 2019

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

zitosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IDA ^ingelesa

TAS ^ingelesa

2 erreferentzia

8 apirila 2019

GOA ^ingelesa

Reactome ^ingelesa

TAS ^ingelesa

8 apirila 2019

GOA ^ingelesa

Human Protein Atlas ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IDA ^ingelesa

nuclear envelope ^ingelesa

IEA ^ingelesa

Erreferentzia bat

8 apirila 2019

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

ribonucleoside-diphosphate reductase complex ^ingelesa

IEA ^ingelesa

Erreferentzia bat

24 apirila 2018

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23921&geneProductId=UniProtKB:P23921

IEA ^ingelesa

cell projection ^ingelesa

IEA ^ingelesa

Erreferentzia bat

8 apirila 2019

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

neuronal cell body ^ingelesa

IEA ^ingelesa

Erreferentzia bat

8 apirila 2019

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

ribonucleoside-diphosphate reductase complex ^ingelesa

IBA ^ingelesa

IEA ^ingelesa

2 erreferentzia

8 apirila 2019

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

8 apirila 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium ^ingelesa

GOA ^ingelesa

GO Central ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IBA ^ingelesa

IEA ^ingelesa

2 erreferentzia

8 apirila 2019

GOA ^ingelesa

UniProt ^ingelesa

UniProt protein ID ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

8 apirila 2019

GOA ^ingelesa

InterPro ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

metabolismo

IEA ^ingelesa

Erreferentzia bat

8 apirila 2019

GOA ^ingelesa

UniProt ^ingelesa

UniProt protein ID ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

mitosi

IEA ^ingelesa

Erreferentzia bat

8 apirila 2019

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

pyrimidine nucleobase metabolic process ^ingelesa

IEA ^ingelesa

Erreferentzia bat

8 apirila 2019

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

male gonad development ^ingelesa

IEA ^ingelesa

Erreferentzia bat

8 apirila 2019

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

deoxyribonucleotide biosynthetic process ^ingelesa

IEA ^ingelesa

ISS ^ingelesa

2 erreferentzia

24 apirila 2018

GOA ^ingelesa

UniProt ^ingelesa

UniProt protein ID ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23921&geneProductId=UniProtKB:P23921

ISS ^ingelesa

24 apirila 2018

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23921&geneProductId=UniProtKB:P23921

IEA ^ingelesa

response to ionizing radiation ^ingelesa

IEA ^ingelesa

Erreferentzia bat

8 apirila 2019

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

cell proliferation in forebrain ^ingelesa

IEA ^ingelesa

Erreferentzia bat

8 apirila 2019

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

protein complex oligomerization ^ingelesa

IEA ^ingelesa

Erreferentzia bat

8 apirila 2019

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

protein heterotetramerization ^ingelesa

IEA ^ingelesa

Erreferentzia bat

8 apirila 2019

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

retina development in camera-type eye ^ingelesa

IEA ^ingelesa

Erreferentzia bat

8 apirila 2019

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

deoxyribonucleotide biosynthetic process ^ingelesa

IBA ^ingelesa

IEA ^ingelesa

ISS ^ingelesa

3 erreferentzia

8 apirila 2019

GOA ^ingelesa

UniProt ^ingelesa

UniProt protein ID ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

ISS ^ingelesa

8 apirila 2019

GOA ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IEA ^ingelesa

8 apirila 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium ^ingelesa

GOA ^ingelesa

GO Central ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

IBA ^ingelesa

nucleobase-containing small molecule interconversion ^ingelesa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23921

TAS ^ingelesa

Erreferentzia bat

8 apirila 2019

GOA ^ingelesa

Reactome ^ingelesa

fisikoki honekin elkarrekintza du

TAS ^ingelesa

clofarabine ^ingelesa

erabilera

Entzimen inhibitzaile

Erreferentzia bat

IUPHAR/BPS Guide to PHARMACOLOGY ^ingelesa

Guide to Pharmacology Ligand ID ^ingelesa

6802

17 abuztua 2016

Entzimen inhibitzaile

Erreferentzia bat

IUPHAR/BPS Guide to PHARMACOLOGY ^ingelesa

Guide to Pharmacology Ligand ID ^ingelesa

4793

17 abuztua 2016

hydroxycarbamide ^ingelesa

erabilera

Entzimen inhibitzaile

Erreferentzia bat

IUPHAR/BPS Guide to PHARMACOLOGY ^ingelesa

Guide to Pharmacology Ligand ID ^ingelesa

6822

17 abuztua 2016

fludarabine phosphate ^ingelesa

honako rola dauka

Inhibitzaile

Erreferentzia bat

Open Targets Platform ^ingelesa

14 abuztua 2023

https://platform.opentargets.org/drug/CHEMBL1096882

hydroxycarbamide ^ingelesa

honako rola dauka

Inhibitzaile

Erreferentzia bat

Open Targets Platform ^ingelesa

14 abuztua 2023

https://platform.opentargets.org/drug/CHEMBL467

gemcitabine hydrochloride ^ingelesa

honako rola dauka

Inhibitzaile

Erreferentzia bat

Open Targets Platform ^ingelesa

14 abuztua 2023

https://platform.opentargets.org/drug/CHEMBL1637

Identifikatzaileak

MeSH identifikadorea

C475286

nola izendatua

RRM1 protein, human

0 erreferentzia

RefSeq protein ID ^ingelesa

NP_001024

Erreferentzia bat

NCBI Gene ^ingelesa

30 maiatza 2020

Erreferentzia bat

NCBI Gene ^ingelesa

30 maiatza 2020

Erreferentzia bat

NCBI Gene ^ingelesa

30 maiatza 2020

Erreferentzia bat

NCBI Gene ^ingelesa

30 maiatza 2020

6240

UniProt protein ID ^ingelesa

Erreferentzia bat

UniProt ^ingelesa

13 azaroa 2019

UniProt protein ID ^ingelesa

Ensembl protein ID ^ingelesa

ENSP00000300738

Erreferentzia bat

Ensembl Release 99 ^ingelesa

Ensembl protein ID ^ingelesa

ENSP00000300738

ENSP00000431464

Erreferentzia bat

Ensembl Release 99 ^ingelesa

Ensembl protein ID ^ingelesa

ENSP00000431464

ENSP00000432555

Erreferentzia bat

Ensembl Release 99 ^ingelesa

Ensembl protein ID ^ingelesa

ENSP00000432555

ENSP00000434069

Erreferentzia bat

Ensembl Release 99 ^ingelesa

Ensembl protein ID ^ingelesa

ENSP00000434069

ENSP00000435656

Erreferentzia bat

Ensembl Release 99 ^ingelesa

Ensembl protein ID ^ingelesa

ENSP00000435656

ENSP00000436377

Erreferentzia bat

Ensembl Release 99 ^ingelesa

Ensembl protein ID ^ingelesa

Erreferentzia bat

UniProt ^ingelesa

UniProt protein ID ^ingelesa

9 abuztua 2016

3HNC

Erreferentzia bat

UniProt ^ingelesa

UniProt protein ID ^ingelesa

9 abuztua 2016

3HND

Erreferentzia bat

UniProt ^ingelesa

UniProt protein ID ^ingelesa

9 abuztua 2016

3HNE

Erreferentzia bat

UniProt ^ingelesa

UniProt protein ID ^ingelesa

9 abuztua 2016

3HNF

Erreferentzia bat

UniProt ^ingelesa

UniProt protein ID ^ingelesa

9 abuztua 2016

5D1Y

Erreferentzia bat

UniProt ^ingelesa

UniProt protein ID ^ingelesa

9 abuztua 2016

4X3V

Erreferentzia bat

UniProt ^ingelesa

UniProt protein ID ^ingelesa

9 abuztua 2016

UMLS CUI

C1259395

Erreferentzia bat

based on heuristic ^ingelesa

inferred by common MeSH mappings on source and on Wikidata ^ingelesa

UMLS 2023 ^ingelesa