Interactomic and pharmacological insights on human sirt-1 (Q21129288)

15 August 2022

3

Susan Costantini

Susan

Costantini

1 reference

15 August 2022

Vasu Gautam

2

Vasu

Gautam

1 reference

15 August 2022

Antonella Paladino

series ordinal

4

author given names

Antonella

author last names

Paladino

1 reference

15 August 2022

Giovanni Colonna

series ordinal

5

author given names

Giovanni

author last names

Colonna

1 reference

Frontiers in Pharmacology

15 August 2022

language of work or name

English

0 references

publication date

2012

0 references

published in

0 references

volume

3

0 references

page(s)

40

0 references

describes a project that uses

Cytoscape

1 reference

Europe PubMed Central

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

cites work

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SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1

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Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

19 March 2017

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19 March 2017

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19 March 2017

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Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses

19 March 2017

1 reference

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Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications

19 March 2017

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High-betweenness proteins in the yeast protein interaction network

19 March 2017

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Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases

19 March 2017

1 reference

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Network biology: understanding the cell's functional organization

19 March 2017

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Comparative protein structure modeling of genes and genomes

19 March 2017

1 reference

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Collective dynamics of 'small-world' networks

19 March 2017

1 reference

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Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1

19 March 2017

1 reference

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Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

19 March 2017

1 reference

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Principles of docking: An overview of search algorithms and a guide to scoring functions

19 March 2017

1 reference

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Computer analysis of protein-protein interaction

19 March 2017

1 reference

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Modulation of SIRT1 expression in different neurodegenerative models and human pathologies

19 March 2017

1 reference

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AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Human Protein Reference Database--2009 update

7 April 2017

1 reference

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BiNGO: a Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks

7 April 2017

1 reference

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Lethality and centrality in protein networks

7 April 2017

1 reference

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Evidence for dynamically organized modularity in the yeast protein-protein interaction network

7 April 2017

1 reference

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Glide: a new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Hierarchical organization of modularity in metabolic networks

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Post-translational modifications and activation of p53 by genotoxic stresses

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

SIRT1-independent mechanisms of the putative sirtuin enzyme activators SRT1720 and SRT2183.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Sirtuin activators: designing molecules to extend life span.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Human sirt-1: molecular modeling and structure-function relationships of an unordered protein

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Shadows of complexity: what biological networks reveal about epistasis and pleiotropy

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Discovery of imidazo[1,2-b]thiazole derivatives as novel SIRT1 activators

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Phosphorylation regulates SIRT1 function.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Principles of flexible protein-protein docking

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Hubba: hub objects analyzer--a framework of interactome hubs identification for network biology

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Resveratrol: a multitargeted agent for age-associated chronic diseases.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Fuzzy complexes: polymorphism and structural disorder in protein-protein interactions

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Graph theory and networks in Biology.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

The modular nature of genetic diseases.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Design and synthesis of compounds that extend yeast replicative lifespan

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Why do hubs tend to be essential in protein networks?

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

SIRT1 and endocrine signaling

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Comparative studies of the antioxidant effects of cis- and trans-resveratrol

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Genomic analysis of essentiality within protein networks

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Treatment with SRT1720, a SIRT1 activator, ameliorates fatty liver with reduced expression of lipogenic enzymes in MSG mice.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

JNK2-dependent regulation of SIRT1 protein stability

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damage

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Analyzing biological network parameters with CentiScaPe

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Loop modeling: Sampling, filtering, and scoring

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Cytoscape: Software for Visualization and Analysis of Biological Networks

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Discovery of oxazolo[4,5-b]pyridines and related heterocyclic analogs as novel SIRT1 activators

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Computing topological parameters of biological networks.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Robustness of the p53 network and biological hackers.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Protein networks, pleiotropy and the evolution of senescence.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Functional topology in a network of protein interactions

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Differential regulation of the Sir2 histone deacetylase gene family by inhibitors of class I and II histone deacetylases

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Potential mechanism by which resveratrol, a red wine constituent, protects neurons

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311038

Disordered domains and high surface charge confer hubs with the ability to interact with multiple proteins in interaction networks

29 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22470339

12 December 2020

inferred from PubMed ID database lookup

Centers of complex networks

1 reference

https://pubmed.ncbi.nlm.nih.gov/22470339

12 December 2020

inferred from PubMed ID database lookup

Principles of docking: An overview of search algorithms and a guide to scoring functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22470339

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.3389/FPHAR.2012.00040

0 references

PMC publication ID

3311038

0 references