SET and MYND domain containing 2 (Q21990632)

http://www.ebi.ac.uk/interpro/protein/Q8R5A0

Zinc finger, MYND-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

SET domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

histone methyltransferase activity (H3-K36 specific)

1 reference

14 February 2019

Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

protein-lysine N-methyltransferase activity

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

RNA polymerase II complex binding

1 reference

14 February 2019

Cardiac deletion of Smyd2 is dispensable for mouse heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

histone-lysine N-methyltransferase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

3 references

14 February 2019

Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

14 February 2019

Cardiac deletion of Smyd2 is dispensable for mouse heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

14 February 2019

Repression of p53 activity by Smyd2-mediated methylation

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

methyltransferase activity

IPI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

14 February 2019

Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

14 February 2019

Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

14 February 2019

Cardiac deletion of Smyd2 is dispensable for mouse heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

14 February 2019

Cardiac deletion of Smyd2 is dispensable for mouse heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

peptidyl-lysine monomethylation

biological process

3 references

histone lysine methylation

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

negative regulation of cell population proliferation

1 reference

14 February 2019

Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

regulation of transcription, DNA-templated

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R5A0&geneProductId=UniProtKB:Q8R5A0

transcription, DNA-templated

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R5A0&geneProductId=UniProtKB:Q8R5A0

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

negative regulation of transcription by RNA polymerase II

3 references

peptidyl-lysine dimethylation

1 reference

14 February 2019

Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

regulation of DNA damage response, signal transduction by p53 class mediator

3 references

1 reference

14 February 2019

Pax3/7BP is a Pax7- and Pax3-binding protein that regulates the proliferation of muscle precursor cells by an epigenetic mechanism

GOA

curator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

histone H3-K36 methylation

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R5A0

chromatin organization

1 reference

14 February 2019

has part(s)

Zinc finger, MYND-type

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8R5A0

SET domain

1 reference

stated in

InterPro Release 71.0