Trefoil factor 2 (Q21991249)

mouse protein (annotated by UniProtKB/Swiss-Prot Q03404)

Spasmolytic polypeptide
SP

Language	Label	Description	Also known as
English	Trefoil factor 2	mouse protein (annotated by UniProtKB/Swiss-Prot Q03404)	Spasmolytic polypeptide SP

Statements

instance of

protein

0 references

part of

P-type trefoil, chordata

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q03404

P-type trefoil domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

P-type trefoil, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

10 August 2016

language of work or name

1 reference

10 August 2016

language of work or name

English

molecular function

CXCR4 chemokine receptor binding

1 reference

31 January 2018

Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03404&geneProductId=UniProtKB:Q03404

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03404

determination method

IEA

intracellular anatomical structure

1 reference

10 September 2018

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03404&geneProductId=UniProtKB:Q03404

3 references

14 February 2019

Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03404

14 February 2019

A novel gastrokine, Gkn3, marks gastric atrophy and shows evidence of adaptive gene loss in humans

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03404

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03404

determination method

IBA

biological process

chemokine-mediated signaling pathway

1 reference

31 January 2018

Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03404&geneProductId=UniProtKB:Q03404

determination method

IGI

negative regulation of macrophage activation

1 reference

14 February 2019

Trefoil family factor 2 is expressed in murine gastric and immune cells and controls both gastrointestinal inflammation and systemic immune responses

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03404

determination method

IMP

negative regulation of gastric acid secretion

1 reference

31 January 2018

TFF2/SP-deficient mice show decreased gastric proliferation, increased acid secretion, and increased susceptibility to NSAID injury

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03404&geneProductId=UniProtKB:Q03404

determination method

IMP

regulation of cell migration

1 reference

14 February 2019

Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03404

determination method

IGI

negative regulation of inflammatory response

determination method

IMP

2 references

positive regulation of cell population proliferation

determination method

IGI

IMP

calcium-mediated signaling

1 reference

14 February 2019

Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03404

determination method

IDA

positive regulation of ERK1 and ERK2 cascade

1 reference

14 February 2019

Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03404

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03404&geneProductId=UniProtKB:Q03404

determination method

IBA

maintenance of gastrointestinal epithelium

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03404

determination method

IBA

negative regulation of gastric acid secretion

P-type trefoil, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q03404

P-type trefoil domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q03404

Identifiers

1 reference

10 August 2016

language of work or name

1 reference

7 January 2016

http://www.uniprot.org/uniprot/Q03404.txt?version=97

1 reference

7 January 2016

http://www.uniprot.org/uniprot/Q03404.txt?version=97

1 reference

7 January 2016

http://www.uniprot.org/uniprot/Q03404.txt?version=97

Trefoil factor 2 (Q21991249)

Statements

Identifiers

Sitelinks

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Trefoil factor 2 (Q21991249)

Statements

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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