The importance of cytochrome P450 2B6 in the human metabolism of environmental chemicals (Q23912648)

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2 February 2024

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25 September 2023

Cytochrome P450 pharmacogenetics as a predictor of toxicity and clinical response to pulse cyclophosphamide in lupus nephritis

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

In vitro human phase I metabolism of xenobiotics I: pesticides and related compounds used in agriculture and public health, May 2003

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

The role of 12 cDNA-expressed human, rodent, and rabbit cytochromes P450 in the metabolism of benzo[a]pyrene and benzo[a]pyrene trans-7,8-dihydrodiol

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Herbicide resistance in transgenic plants with mammalian P450 monooxygenase genes

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Specificity of cDNA-expressed human and rodent cytochrome P450s in the oxidative metabolism of the potent carcinogen 7,12-dimethylbenz[a]anthracene

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Human liver microsomes are efficient catalysts of 1,3-butadiene oxidation: evidence for major roles by cytochromes P450 2A6 and 2E1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Metabolism of highly persistent PCB congener, 2,4,5,2',4',5'-hexachlorobiphenyl, by human CYP2B6.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Diazinon is activated by CYP2C19 in human liver

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Studies of the binding of sulfur released in the mixed-function oxidase-catalyzed metabolism of diethyl p-nitrophenyl phosphorothionate(parathion) to diethyl p-nitrophenyl phosphate (paraoxon).

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Substrates of human hepatic cytochrome P450 3A4.

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Regio- and stereo-selective metabolism of phenanthrene by twelve cDNA-expressed human, rodent, and rabbit cytochromes P-450.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

In vitro metabolism of fipronil by human and rat cytochrome P450 and its interactions with testosterone and diazepam

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

In vitro metabolism of carbofuran by human, mouse, and rat cytochrome P450 and interactions with chlorpyrifos, testosterone, and estradiol

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

The metabolism of nonane, a JP-8 jet fuel component, by human liver microsomes, P450 isoforms and alcohol dehydrogenase and inhibition of human P450 isoforms by JP-8.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Influence of genetic polymorphisms of styrene-metabolizing enzymes and smoking habits on levels of urinary metabolites after occupational exposure to styrene.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Toluene metabolism by cDNA-expressed human hepatic cytochrome P450

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Inhibitory monoclonal antibody to human cytochrome P450 2B6.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

In vitro metabolism of carbaryl by human cytochrome P450 and its inhibition by chlorpyrifos

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

In vitro metabolism of alachlor by human liver microsomes and human cytochrome P450 isoforms

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Smoking, alcoholism and genetic polymorphisms alter CYP2B6 levels in human brain

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

CYP-specific bioactivation of four organophosphorothioate pesticides by human liver microsomes.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Evidence for the activation of organophosphate pesticides by cytochromes P450 3A4 and 2D6 in human liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

The role of CYP forms in the metabolism and metabolic activation of HCFCs and other halocarbons

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Imidacloprid insecticide metabolism: human cytochrome P450 isozymes differ in selectivity for imidazolidine oxidation versus nitroimine reduction

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

The role of metabolism in determining susceptibility to parathion toxicity in man.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Kinetic parameters of OPT pesticide desulfuration by c-DNA expressed human CYPs.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Catalytic characteristics of CYP3A4: requirement for a phenolic function in ortho hydroxylation of estradiol and mono-O-demethylated methoxychlor

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Phytoremediation of the herbicides atrazine and metolachlor by transgenic rice plants expressing human CYP1A1, CYP2B6, and CYP2C19

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Styrene Metabolism by cDNA-Expressed Human Hepatic and Pulmonary Cytochromes P450

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Identification of enzymes involved in the metabolism of atrazine, terbuthylazine, ametryne, and terbutryne in human liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

The influence of CYP2B6, CYP2C9 and CYP2D6 genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man.

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Biotransformation of chlorpyrifos and diazinon by human liver microsomes and recombinant human cytochrome P450s (CYP).

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Cytochrome P450 isozymes responsible for the metabolism of toluene and styrene in human liver microsomes

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Organophosphorus chemicals: potent inhibitors of the human metabolism of steroid hormones and xenobiotics

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

The role of CYP2B6 in human xenobiotic metabolism

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Human metabolism and metabolic interactions of deployment-related chemicals

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Activation of trans-1,2-dihydro-1,2-dihydroxy-6-aminochrysene to genotoxic metabolites by rat and human cytochromes P450.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Metabolic activation of the potent carcinogen dibenzo[a,l]pyrene by human recombinant cytochromes P450, lung and liver microsomes

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Examination of purported probes of human CYP2B6.

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Pharmacogenetic investigation of smoking cessation treatment

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Bupropion and 4-OH-bupropion pharmacokinetics in relation to genetic polymorphisms in CYP2B6

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Malathion bioactivation in the human liver: the contribution of different cytochrome p450 isoforms

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

In vitro metabolism of naphthalene by human liver microsomal cytochrome P450 enzymes

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Stereoselective metabolism of endosulfan by human liver microsomes and human cytochrome P450 isoforms

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Metabolism of endosulfan-alpha by human liver microsomes and its utility as a simultaneous in vitro probe for CYP2B6 and CYP3A4

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Inhibition of the human liver microsomal and human cytochrome P450 1A2 and 3A4 metabolism of estradiol by deployment-related and other chemicals.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Enantioselective metabolism of the endocrine disruptor pesticide methoxychlor by human cytochromes P450 (P450s): major differences in selective enantiomer formation by various P450 isoforms

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

In vitro human metabolism and interactions of repellent N,N-diethyl-m-toluamide

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Metabolism of the endocrine disruptor pesticide-methoxychlor by human P450s: pathways involving a novel catechol metabolite

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Inhibition and activation of the human liver microsomal and human cytochrome P450 3A4 metabolism of testosterone by deployment-related chemicals

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Functional characterization of cytochrome P450 2B6 allelic variants

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

In vitro sulfoxidation of thioether compounds by human cytochrome P450 and flavin-containing monooxygenase isoforms with particular reference to the CYP2C subfamily

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Multiple novel nonsynonymous CYP2B6 gene polymorphisms in Caucasians: demonstration of phenotypic null alleles

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Toxicology of thiono-sulfur compounds

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Induction of cytochrome P4501A1.

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Regulation of cyp3a gene transcription by the pregnane x receptor

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https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Metabolism of n-hexane by rat liver and extrahepatic tissues and the effect of cytochrome P-450 inducers

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021

Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2006.10.002

7 January 2021