Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury (Q23914951)

16

Peter Wipf

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Valerian E. Kagan

17

Valerian E Kagan

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Yulia Y. Tyurina

7

Yulia Y Tyurina

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Patrick M. Kochanek

15

Patrick M Kochanek

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author name string

Jing Ji

1

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Anthony E Kline

2

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Andrew Amoscato

3

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Alejandro K Samhan-Arias

4

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Louis J Sparvero

5

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Vladimir A Tyurin

6

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Bruno Fink

8

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Mioara D Manole

9

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Ava M Puccio

10

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David O Okonkwo

11

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Jeffrey P Cheng

12

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Henry Alexander

13

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Robert S B Clark

14

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language of work or name

English

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publication date

October 2012

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1 reference

8 December 2019

15

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issue

10

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page(s)

1407-13

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performing organization

University of Pittsburgh

University of Pittsburgh at Pittsburgh

1 reference

NIOSHTIC-2

on focus list of Wikimedia project

2 February 2024

Wikimedia–NIOSH collaboration

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1 reference

25 September 2023

Chemistry and antihypertensive effects of tempol and other nitroxides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Selective early cardiolipin peroxidation after traumatic brain injury: an oxidative lipidomics analysis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Permeabilization of the mitochondrial outer membrane by Bax/truncated Bid (tBid) proteins as sensitized by cardiolipin hydroperoxide translocation: mechanistic implications for the intrinsic pathway of oxidative apoptosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Traumatic brain injury--football, warfare, and long-term effects

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Cytochrome c release from mitochondria proceeds by a two-step process

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Mitochondrial injury after mechanical stretch of cortical neurons in vitro: biomarkers of apoptosis and selective peroxidation of anionic phospholipids

19 March 2017

1 reference

https://api.crossref.org/works/10.1038/NN.3195

Cardiolipin: characterization of distinct oxidized molecular species

22 April 2017

1 reference

https://api.crossref.org/works/10.1038/NN.3195

The role of lipids in VDAC oligomerization

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Neuroprotection by acetyl-L-carnitine after traumatic injury to the immature rat brain

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Protection of pancreatic beta-cells by group VIA phospholipase A(2)-mediated repair of mitochondrial membrane peroxidation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Clinical trials in traumatic brain injury: past experience and current developments.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Cell death mechanisms and modulation in traumatic brain injury

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Lipidomic analysis and electron transport chain activities in C57BL/6J mouse brain mitochondria

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

The chemistry and biology of nitroxide compounds

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Initiation of apoptotic signal by the peroxidation of cardiolipin of mitochondria

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Assessment of antioxidant reserves and oxidative stress in cerebrospinal fluid after severe traumatic brain injury in infants and children

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Brain-specific lipids from marine, lacustrine, or terrestrial food resources: potential impact on early African Homo sapiens

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Cell damage in the brain: a speculative synthesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Cognitive deficits following traumatic brain injury produced by controlled cortical impact

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

A mitochondria-targeted nitroxide is reduced to its hydroxylamine by ubiquinol in mitochondria

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Reversible reduction of nitroxides to hydroxylamines: roles for ascorbate and glutathione

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Transient Formation of Superoxide Radicals in Polyunsaturated Fatty Acid-Induced Brain Swelling

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

30 May 2018

Traumatic brain injury

1 reference

Impaired cerebral mitochondrial function after traumatic brain injury in humans

21 January 2018

1 reference

Mitochondrial targeting of selective electron scavengers: synthesis and biological analysis of hemigramicidin-TEMPO conjugates

21 January 2018

1 reference

Bromocriptine reduces lipid peroxidation and enhances spatial learning and hippocampal neuron survival in a rodent model of focal brain trauma

21 January 2018

1 reference

Improving the outcome of severe head injury with the oxygen radical scavenger polyethylene glycol-conjugated superoxide dismutase: a phase II trial

21 January 2018

1 reference

Cardiolipin and its metabolites move from mitochondria to other cellular membranes during death receptor-mediated apoptosis.

21 January 2018

1 reference

Increased susceptibility to Ca(2+)-induced permeability transition and to cytochrome c release in rat heart mitochondria with aging: effect of melatonin

21 January 2018

1 reference

Interaction of peroxidized cardiolipin with rat-heart mitochondrial membranes: induction of permeability transition and cytochrome c release

21 January 2018

1 reference

Neuroprotective effects of tempol, a catalytic scavenger of peroxynitrite-derived free radicals, in a mouse traumatic brain injury model

21 January 2018

1 reference

Age-dependent differences in glutathione peroxidase activity after traumatic brain injury

21 January 2018

1 reference

Cyclosporin A significantly ameliorates cortical damage following experimental traumatic brain injury in rodents

21 January 2018

1 reference

Peroxynitrite-mediated oxidative damage to brain mitochondria: Protective effects of peroxynitrite scavengers

21 January 2018

1 reference

Cyclosporin A improves brain tissue oxygen consumption and learning/memory performance after lateral fluid percussion injury in rats

21 January 2018

1 reference

Imaging mass spectrometry revealed the production of lyso-phosphatidylcholine in the injured ischemic rat brain

21 January 2018

1 reference

Separation and characterization of cardiolipin molecular species by reverse-phase ion pair high-performance liquid chromatography-mass spectrometry

21 January 2018

1 reference

Polynitroxylated pegylated hemoglobin: a novel neuroprotective hemoglobin for acute volume-limited fluid resuscitation after combined traumatic brain injury and hemorrhagic hypotension in mice

21 January 2018

1 reference

Drug delivery to damaged brain

21 January 2018

1 reference

Oxidative stress-dependent release of mitochondrial cytochrome c after traumatic brain injury.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3697869

Inhibition by free radical scavengers and by cyclooxygenase inhibitors of pial arteriolar abnormalities from concussive brain injury in cats

29 November 2018

1 reference

12 December 2020

Biologically active metal-independent superoxide dismutase mimics

1 reference

12 December 2020

ESR and HPLC-EC analysis of ethanol oxidation to 1-hydroxyethyl radical: rapid reduction and quantification of POBN and PBN nitroxides

1 reference

12 December 2020

Kinetics of superoxide-induced exchange among nitroxide antioxidants and their oxidized and reduced forms

1 reference

12 December 2020

Voltage gating of VDAC is regulated by nonlamellar lipids of mitochondrial membranes

1 reference

12 December 2020

Traumatic Brain Injury in the United States: A Public Health Perspective

2 references

12 December 2020

7 January 2021

inferred from DOI database lookup

Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis

1 reference

7 January 2021

inferred from DOI database lookup

Motor and cognitive functional deficits following diffuse traumatic brain injury in the immature rat

1 reference

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NN.3195

1 reference

Dimensions Publication ID

1047820834

0 references

NIOSHTIC-2 ID

20041901

0 references

1 reference

1 reference

PubMed publication ID

22922784

1 reference