A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression. (Q24531049)

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10 November 2019

title

A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression (English)

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10 November 2019

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4

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10 November 2019

Kian Fan Chung

series ordinal

5

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10 November 2019

Ian M. Adcock

series ordinal

6

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10 November 2019

7

Peter J Barnes

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10 November 2019

2

Sam Lim

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10 November 2019

1

Kazuhiro Ito

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10 November 2019

3

Gaetano Caramori

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10 November 2019

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language of work or name

English

0 references

publication date

17 June 2002

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Proceedings of the National Academy of Sciences of the United States of America

10 November 2019

published in

1 reference

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10 November 2019

volume

99

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10 November 2019

issue

13

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10 November 2019

page(s)

8921-8926

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Pharmacology of the eosinophil

10 November 2019

cites work

1 reference

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Functional assay of NF-kappaB translocation into nuclei by laser scanning cytometry: inhibitory effect by dexamethasone or theophylline

24 March 2017

1 reference

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Theophylline accelerates human granulocyte apoptosis not via phosphodiesterase inhibition

24 March 2017

1 reference

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Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A

24 March 2017

1 reference

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Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12.

7 April 2017

1 reference

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Theophylline in the management of asthma: time for reappraisal?

27 September 2017

1 reference

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Theophylline and selective PDE inhibitors as bronchodilators and smooth muscle relaxants

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124399

Transcription: gene control by targeted histone acetylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124399

Specific antibodies reveal ordered and cell-cycle-related use of histone-H4 acetylation sites in mammalian cells

30 May 2018

1 reference

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Low-dose theophylline reduces eosinophilic inflammation but not exhaled nitric oxide in mild asthma.

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.132556899

Effect of chronic theophylline treatment on the methacholine dose-response curve in allergic asthmatic subjects

21 January 2018

1 reference

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Theophylline. A review of its potential steroid sparing effects in asthma

21 January 2018

1 reference

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Mapping DNA interaction sites of chromosomal proteins using immunoprecipitation and polymerase chain reaction.

21 January 2018

1 reference

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p65-activated histone acetyltransferase activity is repressed by glucocorticoids: mifepristone fails to recruit HDAC2 to the p65-HAT complex

21 January 2018

1 reference

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Histone deacetylase 1 phosphorylation promotes enzymatic activity and complex formation

21 January 2018

1 reference

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Effects of theophylline on inflammatory cells and cytokines in asthmatic subjects: a placebo-controlled parallel group study

21 January 2018

1 reference

12 December 2020

Low-dose theophylline modulates T-lymphocyte activation in allergen-challenged asthmatics

1 reference

12 December 2020

A comparison of low-dose inhaled budesonide plus theophylline and high-dose inhaled budesonide for moderate asthma

1 reference

12 December 2020

Aerosol beclomethasone dipropionate spray compared with theophylline as primary treatment for chronic mild-to-moderate asthma. The American Academy of Allergy, Asthma and Immunology Beclomethasone Dipropionate-Theophylline Study Group

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12 December 2020

Comparison of addition of theophylline to inhaled steroid with doubling of the dose of inhaled steroid in asthma

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12 December 2020

Biochemical methods for analysis of histone deacetylases

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12 December 2020

Theophylline and airway inflammation

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12 December 2020

Theophylline inhibits the release of eosinophil survival cytokines--is Raf-1 the protein kinase A target?

1 reference

12 December 2020

Inflammatory mediators of asthma: an update

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12 December 2020

Steady-state levels of histone acetylation in Saccharomyces cerevisiae

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12 December 2020

Need for theophylline in severe steroid-requiring asthmatics

1 reference

12 December 2020

Theophylline--an immunomodulatory role in asthma?

1 reference

12 December 2020

Aerosol beclomethasone dipropionate compared with theophylline as primary treatment of chronic, mild to moderately severe asthma in children

1 reference

12 December 2020

Anti-inflammatory effects of low-dose oral theophylline in atopic asthma

1 reference

12 December 2020

Immunomodulation by theophylline in asthma. Demonstration by withdrawal of therapy

1 reference

12 December 2020

The prolonged survival of human eosinophils with interleukin-5 and its inhibition by theophylline via apoptosis

1 reference

12 December 2020

Mediators of chronic obstructive pulmonary disease

1 reference

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7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1073/PNAS.132556899

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12070353%20AND%20SRC:MED&resulttype=core&format=json

OpenCitations bibliographic resource ID

10 November 2019

ADS bibcode

2002PNAS...99.8921I

0 references

2993397

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12070353%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

PubMed publication ID

12070353

1 reference