Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP (Q24594281)

3

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author name string

Bo Huang

2

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Qian Chen

4

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Se-Jin Lee

5

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Robert A Anders

6

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Jun O Liu

7

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Duojia Pan

The Hippo Signaling Pathway in Development and Cancer

8

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language of work or name

English

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publication date

15 June 2012

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published in

Genes & Development

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volume

26

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issue

12

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page(s)

1300-5

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cites work

1 reference

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TEAD mediates YAP-dependent gene induction and growth control

24 March 2017

1 reference

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TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm

24 March 2017

1 reference

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Structural basis of YAP recognition by TEAD4 in the Hippo pathway

24 March 2017

1 reference

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Structural insights into the YAP and TEAD complex

24 March 2017

1 reference

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The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

24 March 2017

1 reference

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The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP

24 March 2017

1 reference

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Fluorescence spectra of hematoporphyrin and hematoporphyrin-diacetate aggregates in buffer solution

24 March 2017

1 reference

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Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

24 March 2017

1 reference

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Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

24 March 2017

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YAP1 increases organ size and expands undifferentiated progenitor cells

24 March 2017

1 reference

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Principles of cancer therapy: oncogene and non-oncogene addiction

24 March 2017

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Elucidation of a universal size-control mechanism in Drosophila and mammals

7 April 2017

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Hippo signaling: growth control and beyond

7 April 2017

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The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals

27 September 2017

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The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis.

27 September 2017

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The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals

27 September 2017

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Inhibition of angiogenesis by the antifungal drug itraconazole

27 September 2017

1 reference

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The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis

27 September 2017

1 reference

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Photodynamic therapy with verteporfin: a new treatment in ophthalmology

27 September 2017

1 reference

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Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene

27 September 2017

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The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway

30 May 2018

1 reference

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Ability of scalloped deletion constructs to rescue sd mutant wing phenotypes in Drosophila melanogaster.

28 November 2018

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Novobiocin induces a distinct conformation of Hsp90 and alters Hsp90-cochaperone-client interactions

28 November 2018

1 reference

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28 November 2018

Identifiers

DOI

10.1101/GAD.192856.112

1 reference

1 reference

1 reference

PubMed publication ID

22677547

1 reference