Promoter methylation status of hMLH1, MGMT, and CDKN2A/p16 in colorectal adenomas (Q24603535)

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Chryssoula Kalogera

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Nikolaos Tzambouras

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Dimitrios Stephanou

4

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Epameinondas Tsianos

5

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Konstantin Seferiadis

6

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Georgios Kolios

World Journal of Gastroenterology

7

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language of work or name

English

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publication date

28 July 2010

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published in

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volume

16

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issue

28

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page(s)

3553-60

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cites work

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Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

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Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines

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Aberrantly methylated CDKN2A, MGMT, and MLH1 in colon polyps and in fecal DNA from patients with colorectal polyps.

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Methylation patterns define two types of hyperplastic polyp associated with colorectal cancer

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The relationship between hypomethylation and CpG island methylation in colorectal neoplasia

27 September 2017

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Frequent CpG island methylation in serrated adenomas of the colorectum

27 September 2017

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CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future

27 September 2017

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Genetic and epigenetic alterations in colon cancer

27 September 2017

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CpG island methylation in aberrant crypt foci of the colorectum

27 September 2017

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CpG island methylation in colorectal adenomas

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Epigenetic lesions causing genetic lesions in human cancer: promoter hypermethylation of DNA repair genes

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Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways

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DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer?

27 September 2017

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Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers.

27 September 2017

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Diagnostic microsatellite instability: definition and correlation with mismatch repair protein expression.

27 September 2017

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Alterations in DNA methylation: a fundamental aspect of neoplasia

30 May 2018

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Long-term risk of colorectal cancer after excision of rectosigmoid adenomas.

30 May 2018

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CpG island methylation is frequently present in tubulovillous and villous adenomas and correlates with size, site, and villous component.

30 May 2018

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CpG island methylation as an early event during adenoma progression in carcinogenesis of sporadic colorectal cancer.

28 November 2018

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Aberrant CpG island hypermethylation of multiple genes in colorectal neoplasia.

28 November 2018

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Evaluation of microsatellite instability, hMLH1 expression and hMLH1 promoter hypermethylation in defining the MSI phenotype of colorectal cancer.

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909555

Tumors with microsatellite instability: many mutations, targets and paradoxes

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909555

Frequent loss of hMLH1 by promoter hypermethylation leads to microsatellite instability in adenomatous polyps of patients with a single first-degree member affected by colon cancer.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909555

Low-level microsatellite instability in most colorectal carcinomas

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909555

Methylation of O-6-methylguanine DNA methyltransferase characterizes a subset of colorectal cancer with low-level DNA microsatellite instability

28 November 2018

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12 December 2020

Detection of aberrantly methylated hMLH1 promoter DNA in the serum of patients with microsatellite unstable colon cancer

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12 December 2020

Adenoma characteristics as risk factors for recurrence of advanced adenomas

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12 December 2020

Microsatellite marker analysis in screening for hereditary nonpolyposis colorectal cancer (HNPCC)

1 reference

12 December 2020

Association of K-ras mutations with p16 methylation in human colon cancer

1 reference

12 December 2020

CpG island methylator phenotype in cancer

1 reference

12 December 2020

CpG island methylation of genes accumulates during the adenoma progression step of the multistep pathogenesis of colorectal cancer

1 reference

12 December 2020