Antidiabetic and antisteatotic effects of the selective fatty acid synthase (FAS) inhibitor platensimycin in mouse models of diabetes (Q24629052)

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Jun Wang

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Christine C Chung

4

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Gino Salituro

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Bindhu V Karanam

6

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Sang Ho Lee

7

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Maryann Powles

8

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Kenneth P Ellsworth

9

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Michael E Lassman

10

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Corey Miller

11

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Robert W Myers

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Michael R Tota

13

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Bei B Zhang

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Cai Li

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

29 March 2011

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published in

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volume

108

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issue

13

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page(s)

5378-83

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Fatty acid synthase gene expression in human adipose tissue: association with obesity and type 2 diabetes.

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Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors

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Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens

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Isolation, Structure, and Absolute Stereochemistry of Platensimycin, A Broad Spectrum Antibiotic Discovered Using an Antisense Differential Sensitivity Strategy

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Isolation and Structure of Platencin: A FabH and FabF Dual Inhibitor with Potent Broad-Spectrum Antibiotic Activity

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Fatty acid synthesis and PPARalpha hand in hand

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21389266

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1002588108

1 reference

ADS bibcode

2011PNAS..108.5378W

0 references

1 reference

1 reference

PubMed publication ID

21389266

1 reference