BRCA Mutations, DNA Repair Deficiency, and Ovarian Aging (Q26801732)

2

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Shiny Titus

3

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Robert Stobezki

4

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Lin Liu

Effects of BRCA1 and BRCA2 mutations on female fertility

5

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language of work or name

English

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publication date

September 2015

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published in

Biology of Reproduction

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volume

93

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issue

3

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page(s)

67

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cites work

1 reference

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Association of BRCA1 mutations with occult primary ovarian insufficiency: a possible explanation for the link between infertility and breast/ovarian cancer risks

7 April 2017

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Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

7 April 2017

1 reference

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Cancer susceptibility and the functions of BRCA1 and BRCA2

7 April 2017

1 reference

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Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

7 April 2017

1 reference

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Reversal of female infertility by Chk2 ablation reveals the oocyte DNA damage checkpoint pathway

7 April 2017

1 reference

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Impairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humans

7 April 2017

1 reference

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DNA double strand break repair, chromosome synapsis and transcriptional silencing in meiosis

7 April 2017

1 reference

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Nuclear DNA damage as a direct cause of aging

7 April 2017

1 reference

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Mechanism of homologous recombination: mediators and helicases take on regulatory functions

7 April 2017

1 reference

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Premature menopause in patients with BRCA1 gene mutation

7 April 2017

1 reference

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NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression

7 April 2017

1 reference

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Caspase-2 deficiency prevents programmed germ cell death resulting from cytokine insufficiency but not meiotic defects caused by loss of ataxia telangiectasia-mutated (Atm) gene function

7 April 2017

1 reference

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ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

7 April 2017

1 reference

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Increased DNA damage and repair deficiency in granulosa cells are associated with ovarian aging in rhesus monkey

7 April 2017

1 reference

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Changes in the expression of DNA double strand break repair genes in primordial follicles from immature and aged rats

28 September 2017

1 reference

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Different fates of oocytes with DNA double-strand breaks in vitro and in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Exome sequencing identifies FANCM as a susceptibility gene for triple-negative breast cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

BRCA1 germline mutations may be associated with reduced ovarian reserve

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Stress and DNA repair biology of the Fanconi anemia pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Cancers associated with BRCA1 and BRCA2 mutations other than breast and ovarian

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Hypersensitivity of primordial germ cells to compromised replication-associated DNA repair involves ATM-p53-p21 signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Defying DNA double-strand break-induced death during prophase I meiosis by temporal TAp63α phosphorylation regulation in developing mouse oocytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Double-strand break repair: 53BP1 comes into focus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Age-associated telomere shortening in mouse oocytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Human ovarian tissue cortex surrounding benign and malignant lesions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Chemotherapy-induced amenorrhea in patients with breast cancer with a BRCA1 or BRCA2 mutation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

BRCA1 in the DNA damage response and at telomeres

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Comparison of age at natural menopause in BRCA1/2 mutation carriers with a non-clinic-based sample of women in northern California

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Telomere shortening alters the kinetics of the DNA damage response after ionizing radiation in human cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Telomere DNA deficiency is associated with development of human embryonic aneuploidy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Telomere length is associated with types of chromosome 21 nondisjunction: a new insight into the maternal age effect on Down syndrome birth.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Impact of BRCA mutations on female fertility and offspring sex ratio

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Fertility in women with BRCA mutations: a case-control study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

BRCA1 knock-down causes telomere dysfunction in mammary epithelial cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Telomeres and reproductive aging

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Cell biology of cancer: BRCA1 and sister chromatid pairing reactions?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Meiosis in oocytes: predisposition to aneuploidy and its increased incidence with age.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Cohesin and DNA damage repair

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Spontaneous and therapeutic abortions and the risk of breast cancer among BRCA mutation carriers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Irregular telomeres impair meiotic synapsis and recombination in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Cellular machineries for chromosomal DNA repair.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Playing for half the deck: the molecular biology of meiosis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Impaired DNA damage response in cells expressing an exon 11-deleted murine Brca1 variant that localizes to nuclear foci

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

The evolution of ovarian oocyte decline with aging and possible relationships to Down syndrome and Alzheimer disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Fanconi's anaemia and pregnancy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Accelerated disappearance of ovarian follicles in mid-life: implications for forecasting menopause

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4710189

Chiasma frequency and maternal age in mammals.

28 September 2017

1 reference

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31 May 2018

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Shorter telomere length is associated with increased ovarian cancer risk in both familial and sporadic cases.

21 January 2018

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BRCA1 is required for meiotic spindle assembly and spindle assembly checkpoint activation in mouse oocytes

21 January 2018

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Checkpoint for DNA integrity at the first mitosis after oocyte activation

21 January 2018

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BRCA mutation carriers do not have compromised ovarian reserve.

21 January 2018

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Do BRCA1 and BRCA2 mutation carriers have earlier natural menopause than their noncarrier relatives? Results from the Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer

21 January 2018

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BRCA mutations and fertility: do not push the envelope!

21 January 2018

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A role for Brca1 in chromosome end maintenance

21 January 2018

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Methylnitrosourea as challenge mutagen in assessment of the DNA mismatch repair (MMR) activity: association with some types of cancer

21 January 2018

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Survival of human ovarian follicles from fetal to adult life: apoptosis, apoptosis-related proteins, and transcription factor GATA-4.

28 November 2018

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Frequency of premature menopause in women who carry a BRCA1 or BRCA2 mutation

28 November 2018

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Haploinsufficiency of Parp1 accelerates Brca1-associated centrosome amplification, telomere shortening, genetic instability, apoptosis, and embryonic lethality

21 January 2018

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