Early QT assessment--how can our confidence in the data be improved? (Q27020964)

language of work or name

1 reference

November 2013

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British Journal of Clinical Pharmacology

published in

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volume

76

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issue

5

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page(s)

642-8

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Practice and challenges of thorough QT studies.

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1 reference

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28 September 2017

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Assessing electrocardiographic data quality and possible replacement of pharmacologic positive control in thorough QT/QTc studies by investigations of drug-free QTc stability.

28 September 2017

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Creation of a Knowledge Management System for QT Analyses

28 September 2017

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Electrocardiographic assessment for therapeutic proteins—scientific discussion

28 September 2017

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Statistical characteristics of moxifloxacin-induced QTc effect

28 September 2017

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The thorough QT/QTc study 4 years after the implementation of the ICH E14 guidance

28 September 2017

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Assessing proarrhythmic potential of drugs when optimal studies are infeasible.

28 September 2017

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Concentration-QT relationships play a key role in the evaluation of proarrhythmic risk during regulatory review.

28 September 2017

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Pharmacokinetic-pharmacodynamic modeling in the data analysis and interpretation of drug-induced QT/QTc prolongation

28 September 2017

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Drugs, QT interval prolongation and ICH E14: the need to get it right

28 September 2017

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Quantitative analysis of the disopyramide concentration-effect relationship

28 September 2017

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The effect of quinidine and its metabolites on the electrocardiogram and systolic time intervals: concentration--effect relationships.

28 September 2017

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The pharmacokinetics and pharmacodynamics of oral dofetilide after twice daily and three times daily dosing

28 September 2017

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Effect kinetics of N-acetylprocainamide-induced QT interval prolongation

31 May 2018

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Testing for positive control activity in a thorough QTc study

31 May 2018

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The cost-effectiveness of drug regulation: the example of thorough QT/QTc studies.

21 January 2018

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A population pharmacokinetic-pharmacodynamic analysis and model validation of azimilide

21 January 2018

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Population pharmacokinetics and pharmacodynamics of sotalol in pediatric patients with supraventricular or ventricular tachyarrhythmia

21 January 2018

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Modeling the effect of sevoflurane on corrected QT prolongation: a pharmacodynamic analysis

21 January 2018

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Multiple comparisons of repeatedly measured response: issues of validation testing in thorough QT/QTc clinical trials

21 January 2018

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Improving the precision of QT measurements.

21 January 2018

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International Conference on Harmonisation; guidance on E14 Clinical Evaluation of QT/QTc Interval Prolongation and Proarrhythmic Potential for Non-Antiarrhythmic Drugs; availability. Notice.

28 November 2018

1 reference

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Population Pharmacokinetic and Concentration-QTc Models for Moxifloxacin: Pooled Analysis of 20 Thorough QT Studies

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/23278510

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

0 references

1 reference

PubMed publication ID

23278510

1 reference