Derlin YBR201W (Q27550444)

fungal protein found in Saccharomyces cerevisiae S288c

DER1
derlin
YBR201W

Language	Label	Description	Also known as
English	Derlin YBR201W	fungal protein found in Saccharomyces cerevisiae S288c	DER1 derlin YBR201W

Statements

1 reference

25 May 2022

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P38307

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Endoplasmic Reticular Retrotranslocon

1 reference

Transporter Classification Database ID

3.A.16.1.2

retrieved

2 October 2019

based on heuristic

hierarchical database ID heuristic

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

misfolded protein binding

1 reference

9 May 2019

Der1 promotes movement of misfolded proteins through the endoplasmic reticulum membrane

GOA

curator

SGD

Saccharomyces Genome Database ID

S000000405

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38307

6 references

9 May 2019

Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38307

9 May 2019

High-quality binary protein interaction map of the yeast interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38307

9 May 2019

The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38307

9 May 2019

Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38307

9 May 2019

The ER-associated degradation component Der1p and its homolog Dfm1p are contained in complexes with distinct cofactors of the ATPase Cdc48p

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38307

9 May 2019

Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38307

1 reference

9 May 2019

Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38307

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38307

determination method

IEA

Hrd1p ubiquitin ligase ERAD-L complex

1 reference

9 May 2019

Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins

GOA

curator

SGD

Saccharomyces Genome Database ID

S000000405

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38307

determination method

IDA

endoplasmic reticulum

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38307

determination method

IEA

integral component of membrane

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38307

determination method

IEA

biological process

ubiquitin-dependent ERAD pathway

3 references

9 May 2019

The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment

GOA

curator

SGD

Saccharomyces Genome Database ID

S000000405

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38307

9 May 2019

N-terminal acetylation of the yeast Derlin Der1 is essential for Hrd1 ubiquitin-ligase activity toward luminal ER substrates

GOA

curator

SGD

Saccharomyces Genome Database ID

S000000405

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38307

9 May 2019

Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast

GOA

curator

SGD

Saccharomyces Genome Database ID

S000000405

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38307

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38307

determination method

IEA

retrograde protein transport, ER to cytosol

1 reference

9 May 2019

Der1 promotes movement of misfolded proteins through the endoplasmic reticulum membrane

GOA

curator

SGD

Saccharomyces Genome Database ID

S000000405

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38307

determination method

IMP

misfolded protein transport

1 reference

9 May 2019

Der1 promotes movement of misfolded proteins through the endoplasmic reticulum membrane

GOA

curator

SGD

Saccharomyces Genome Database ID

S000000405

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38307

determination method

IMP

protein quality control for misfolded or incompletely synthesized proteins

1 reference

9 May 2019

Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38307

determination method

IMP

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

Saccharomyces Genome Database ID

1 reference

20 March 2022

Transporter Classification Database ID

3.A.16.1.2

2 references

stated in

Transporter Classification database

retrieved

13 March 2020

stated in

Transporter Classification database

retrieved

29 April 2020

Derlin YBR201W (Q27550444)

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Identifiers

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Derlin YBR201W (Q27550444)

Statements

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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