Determination of the structure of the N-terminal splice region of the cyclic AMP-specific phosphodiesterase RD1 (RNPDE4A1) by 1H NMR and identification of the membrane association domain using chimeric constructs (Q27732838)

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English	Determination of the structure of the N-terminal splice region of the cyclic AMP-specific phosphodiesterase RD1 (RNPDE4A1) by 1H NMR and identification of the membrane association domain using chimeric constructs	scientific article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8663181%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

Determination of the structure of the N-terminal splice region of the cyclic AMP-specific phosphodiesterase RD1 (RNPDE4A1) by 1H NMR and identification of the membrane association domain using chimeric constructs (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8663181%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

Miles D. Houslay

5

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16 October 2019

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K J Smith

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16 October 2019

G Scotland

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16 October 2019

J Beattie

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16 October 2019

I P Trayer

4

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16 October 2019

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1 July 1996

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16 October 2019

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9

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Journal of Biological Chemistry

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16 October 2019

271

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16 October 2019

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16 October 2019

16703-16711

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16 October 2019

Phosphorylation-Dephosphorylation of Enzymes

1 reference

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21 January 2018

Diversity in cyclic nucleotide phosphodiesterase isoenzyme families

1 reference

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Cyclic nucleotide-dependent protein kinases

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The postsynaptic density: a subcellular anchor for signal transduction enzymes

1 reference

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Engineered deletion of the unique N-terminal domain of the cyclic AMP-specific phosphodiesterase RD1 prevents plasma membrane association and the attainment of enhanced thermostability without altering its sensitivity to inhibition by rolipram

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The insulin-stimulated cyclic AMP phosphodiesterase binds to a single class of protein sites on the liver plasma membrane

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Alternative splicing of cAMP-specific phosphodiesterase mRNA transcripts. Characterization of a novel tissue-specific isoform, RNPDE4A8.

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21 January 2018

Identification, characterization and regional distribution in brain of RPDE-6 (RNPDE4A5), a novel splice variant of the PDE4A cyclic AMP phosphodiesterase family

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21 January 2018

Molecular cloning of a novel splice variant of human type IVA (PDE-IVA) cyclic AMP phosphodiesterase and localization of the gene to the p13.2-q12 region of human chromosome 19 [corrected]

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21 January 2018

Chromosome localizations of genes for five cAMP-specific phosphodiesterases in man and mouse

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21 January 2018

Chromosomal localization of the human and rat genes (PDE4D and PDE4B) encoding the cAMP-specific phosphodiesterases 3 and 4

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21 January 2018

Molecular cloning of rat homologues of the Drosophila melanogaster dunce cAMP phosphodiesterase: evidence for a family of genes

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21 January 2018

Molecular biology of the cyclic AMP-specific cyclic nucleotide phosphodiesterases: a diverse family of regulatory enzymes

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21 January 2018

Cloning and characterization of mammalian homologs of the Drosophila dunce+ gene

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21 January 2018

Identification and characterization of the type-IVA cyclic AMP-specific phosphodiesterase RD1 as a membrane-bound protein expressed in cerebellum

1 reference

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21 January 2018

Chimeric constructs show that the unique N-terminal domain of the cyclic AMP phosphodiesterase RD1 (RNPDE4A1A; rPDE-IVA1) can confer membrane association upon the normally cytosolic protein chloramphenicol acetyltransferase

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Attachment of a 40-base-pair G + C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes

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Folding of peptide fragments comprising the complete sequence of proteins. Models for initiation of protein folding. I. Myohemerythrin

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21 January 2018

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

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21 January 2018

Folding of immunogenic peptide fragments of proteins in water solution. I. Sequence requirements for the formation of a reverse turn

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21 January 2018

The alpha-helix dipole and the properties of proteins

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21 January 2018

Stabilization of protein structure by interaction of alpha-helix dipole with a charged side chain

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Helix lap-joints as ion-binding sites: DNA-binding motifs and Ca-binding "EF hands" are related by charge and sequence reversal

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The energetics of ion-pair and hydrogen-bonding interactions in a helical peptide

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21 January 2018

Molecular dynamics simulations of the unfolding of an alpha-helical analogue of ribonuclease A S-peptide in water

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A single carboxy-terminal arginine determines the amino-terminal helix conformation of an alanine-based peptide

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Exploring the peptide 3(10)-helix reversible alpha-helix equilibrium with double label electron spin resonance

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Atomic structure of the actin:DNase I complex

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Influence of proline residues on protein conformation

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Alternative splicing of the type-IVA cyclic AMP phosphodiesterase gene provides isoform variants with distinct N-terminal domains fused to a common, soluble catalytic unit: 'designer' changes in Vmax, stability and membrane association.

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Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

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Tests of the helix dipole model for stabilization of α-helices

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