Cisplatin and fluorouracil with or without panitumumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (SPECTRUM): an open-label phase 3 randomised trial. (Q27852333)

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English	Cisplatin and fluorouracil with or without panitumumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (SPECTRUM): an open-label phase 3 randomised trial.	scientific article

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scholarly article

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PubMed publication ID

13 November 2016

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Cisplatin and fluorouracil with or without panitumumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (SPECTRUM): an open-label phase 3 randomised trial (English)

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2 March 2020

phase III clinical trial

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1 reference

based on heuristic

inferred from title

head and neck squamous cell carcinoma

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Sandrine Faivre

12

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2 March 2020

15

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2 March 2020

Bruce Allen Bach

18

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2 March 2020

Krzysztof Skladowski

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Krzysztof Skladowski

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2 March 2020

Arlene A Forastiere

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2 March 2020

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Jan B Vermorken

1

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2 March 2020

Jan Stöhlmacher-Williams

2

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2 March 2020

Irina Davidenko

3

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2 March 2020

Eric Winquist

5

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2 March 2020

Cristian Villanueva

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2 March 2020

Paolo Foa

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2 March 2020

Sylvie Rottey

8

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2 March 2020

Makoto Tahara

10

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2 March 2020

Vasant R Pai

11

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2 March 2020

Cesar R Blajman

13

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2 March 2020

Kelly S Oliner

16

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2 March 2020

Zhiying Pan

17

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

SPECTRUM investigators

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2 March 2020

publication date

6 June 2013

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2 March 2020

Lancet Oncology Commission

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2 March 2020

14

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2 March 2020

8

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Europe PubMed Central

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2 March 2020

697-710

1 reference

Europe PubMed Central

PubMed publication ID

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2 March 2020

A phase III randomized study comparing cisplatin and fluorouracil as single agents and in combination for advanced squamous cell carcinoma of the head and neck

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamous-cell carcinoma of the head and neck: a Southwest Oncology Group study

1 reference

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7 January 2021

based on heuristic

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Randomized comparison of cisplatin, methotrexate, bleomycin and vincristine (CABO) versus cisplatin and 5-fluorouracil (CF) versus cisplatin (C) in recurrent or metastatic squamous cell carcinoma of the head and neck

1 reference

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7 January 2021

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Randomized phase III evaluation of cisplatin plus fluorouracil versus cisplatin plus paclitaxel in advanced head and neck cancer (E1395): an intergroup trial of the Eastern Cooperative Oncology Group

1 reference

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7 January 2021

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Phase III randomized trial of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/recurrent head and neck cancer: an Eastern Cooperative Oncology Group study

1 reference

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The molecular biology of head and neck cancer

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Functional genomic analysis identified epidermal growth factor receptor activation as the most common genetic event in oral squamous cell carcinoma

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Platinum-based chemotherapy plus cetuximab in head and neck cancer

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7 January 2021

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Exploring biomarkers in head and neck cancer

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7 January 2021

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Evidence for a causal association between human papillomavirus and a subset of head and neck cancers

1 reference

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7 January 2021

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Human papillomavirus and survival of patients with oropharyngeal cancer.

1 reference

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Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial

1 reference

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Survival and human papillomavirus in oropharynx cancer in TAX 324: a subset analysis from an international phase III trial.

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Prognostic significance of p16INK4A and human papillomavirus in patients with oropharyngeal cancer treated on TROG 02.02 phase III trial

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Burden of potentially human papillomavirus-associated cancers of the oropharynx and oral cavity in the US, 1998-2003.

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Genetic patterns in head and neck cancers that contain or lack transcriptionally active human papillomavirus

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E6 and e7 gene silencing and transformed phenotype of human papillomavirus 16-positive oropharyngeal cancer cells

1 reference

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HPV integration begins in the tonsillar crypt and leads to the alteration of p16, EGFR and c-myc during tumor formation.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

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EGFR, p16, HPV Titer, Bcl-xL and p53, sex, and smoking as indicators of response to therapy and survival in oropharyngeal cancer

1 reference

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inferred from DOI database lookup

Relationship between epidermal growth factor receptor status, p16(INK4A), and outcome in head and neck squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Relationships between epidermal growth factor receptor expression and human papillomavirus status as markers of prognosis in oropharyngeal cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

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Molecular and Cytogenetic Subgroups of Oropharyngeal Squamous Cell Carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2813%2970181-5

7 January 2021

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inferred from DOI database lookup

Panitumumab in combination with cytotoxic chemotherapy for the treatment of metastatic colorectal carcinoma

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Augmentation of radiation response by panitumumab in models of upper aerodigestive tract cancer

1 reference

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Safety, pharmacokinetics, and activity of ABX-EGF, a fully human anti-epidermal growth factor receptor monoclonal antibody in patients with metastatic renal cell cancer

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New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

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Comparing ELISA and surface plasmon resonance for assessing clinical immunogenicity of panitumumab

1 reference

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7 January 2021

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inferred from DOI database lookup

Interval estimation for the difference between independent proportions: comparison of eleven methods

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Prognostic factors and long-term survivorship in patients with recurrent or metastatic carcinoma of the head and neck.

1 reference

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7 January 2021

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inferred from DOI database lookup

Human Papillomavirus Types in Head and Neck Squamous Cell Carcinomas Worldwide: A Systematic Review

1 reference

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inferred from DOI database lookup

Partial p16 staining in oropharyngeal squamous cell carcinoma: extent and pattern correlate with human papillomavirus RNA status

1 reference

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inferred from DOI database lookup

Is p16 immunohistochemistry a more cost-effective method for identification of human papilloma virus-associated head and neck squamous cell carcinoma?

1 reference

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based on heuristic

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Tissue distribution of human papillomavirus 16 DNA integration in patients with tonsillar carcinoma

1 reference

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based on heuristic

inferred from DOI database lookup

A subset of head and neck squamous cell carcinomas exhibits integration of HPV 16/18 DNA and overexpression of p16INK4A and p53 in the absence of mutations in p53 exons 5–8

1 reference

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1 reference

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inferred from DOI database lookup

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1 reference

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inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

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inferred from DOI database lookup

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10.1016/S1470-2045(13)70181-5

2 references

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

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1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746666%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

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