Itk/Emt/Tsk activation in response to CD3 cross-linking in Jurkat T cells requires ZAP-70 and Lat and is independent of membrane recruitment (Q28145381)

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scientific article (publication date: 8 October 1999)

Language	Label	Description	Also known as
English	Itk/Emt/Tsk activation in response to CD3 cross-linking in Jurkat T cells requires ZAP-70 and Lat and is independent of membrane recruitment	scientific article (publication date: 8 October 1999)

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scholarly article

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Itk/Emt/Tsk activation in response to CD3 cross-linking in Jurkat T cells requires ZAP-70 and Lat and is independent of membrane recruitment (English)

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author name string

X Shan

1

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R L Wange

2

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language of work or name

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publication date

8 October 1999

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Journal of Biological Chemistry

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274

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41

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29323-30

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Leukocyte protein tyrosine kinases: potential targets for drug discovery

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T cell antigen receptor signal transduction

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Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

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Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes

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F2(Pmp)2-TAM zeta 3, a novel competitive inhibitor of the binding of ZAP-70 to the T cell antigen receptor, blocks early T cell signaling

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Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling

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Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T-cell line

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Complex complexes: signaling at the TCR.

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The role of Grb2-associated proteins in T-cell activation

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Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function

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Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2

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LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

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Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation

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Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

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LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

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Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains

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Engagement of GPI-linked CD48 contributes to TCR signals and cytoskeletal reorganization: a role for lipid rafts in T cell activation

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Membrane compartmentation is required for efficient T cell activation.

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Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice

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The spectrum of mutations in Btk that cause X-linked agammaglobulinemia

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The Btk subfamily of cytoplasmic tyrosine kinases: structure, regulation and function

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itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2

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A novel human tyrosine kinase gene inducible in T cells by interleukin 2

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CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line

1 reference

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Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk.

1 reference

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T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells

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Regulatory intramolecular association in a tyrosine kinase of the Tec family

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Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity

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Activation of Tsk and Btk tyrosine kinases by G protein beta gamma subunits

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Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the Pleckstrin homology domain of inducible T cell kinase

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Phosphatidylinositol-3,4,5-trisphosphate (PtdIns-3,4,5-P3)/Tec kinase-dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals

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A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains

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Tyrosine phosphorylation and activation of Bruton tyrosine kinase upon Fc epsilon RI cross-linking

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Phosphatidylinositol 3-kinase-gamma activates Bruton's tyrosine kinase in concert with Src family kinases

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SHIP modulates immune receptor responses by regulating membrane association of Btk.

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ZAP-70-dependent and -independent activation of Erk in Jurkat T cells. Differences in signaling induced by H2o2 and Cd3 cross-linking

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LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

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Expression, purification, and characterization of the functional dimeric cytoplasmic domain of human erythrocyte band 3 in Escherichia coli

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Constitutive membrane association potentiates activation of Bruton tyrosine kinase

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Functional rafts in cell membranes

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Functions of lipid rafts in biological membranes

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Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

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Large, detergent-resistant complexes containing murine antigens Thy-1 and Ly-6 and protein tyrosine kinase p56lck.

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Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

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Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.

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Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate.

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