Structure-function relationships of the raloxifene-estrogen receptor-alpha complex for regulating transforming growth factor-alpha expression in breast cancer cells (Q28343990)

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English	Structure-function relationships of the raloxifene-estrogen receptor-alpha complex for regulating transforming growth factor-alpha expression in breast cancer cells	scientific article

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scholarly article

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Structure-function relationships of the raloxifene-estrogen receptor-alpha complex for regulating transforming growth factor-alpha expression in breast cancer cells (English)

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V. Craig Jordan

9

object named as

V Craig Jordan

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author name string

Hong Liu

1

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Woo-Chan Park

2

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David J Bentrem

3

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Kevin P McKian

4

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Alexander De Los Reyes

5

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Jessica A Loweth

6

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Jennifer MacGregor Schafer

7

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James W Zapf

8

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language of work or name

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publication date

15 March 2002

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Journal of Biological Chemistry

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277

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11

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9189-98

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3696956/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

The effect of raloxifene on risk of breast cancer in postmenopausal women: results from the MORE randomized trial. Multiple Outcomes of Raloxifene Evaluation

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20 March 2017

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

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20 March 2017

Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

20 March 2017

Basic guide to the mechanisms of antiestrogen action

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

20 March 2017

Isoforms of steroid receptor co-activator 1 differ in their ability to potentiate transcription by the oestrogen receptor

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

20 March 2017

Molecular basis of agonism and antagonism in the oestrogen receptor

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

20 March 2017

Estrogen receptor-associated proteins: possible mediators of hormone-induced transcription

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

20 March 2017

Sequence of the pS2 mRNA induced by estrogen in the human breast cancer cell line MCF-7

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

20 March 2017

Effects of tamoxifen on bone mineral density in postmenopausal women with breast cancer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

20 March 2017

Tamoxifen for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

7 April 2017

ER beta inhibits proliferation and invasion of breast cancer cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

29 September 2017

Estrogen receptor interaction with estrogen response elements

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

29 September 2017

Estrogen response element sequence impacts the conformation and transcriptional activity of estrogen receptor alpha

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

29 September 2017

Molecular mechanism of action at estrogen receptor alpha of a new clinically relevant antiestrogen (GW7604) related to tamoxifen

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

29 September 2017

Allosteric silencing of activating function 1 in the 4-hydroxytamoxifen estrogen receptor complex is induced by substituting glycine for aspartate at amino acid 351.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

29 September 2017

Raloxifene hydrochloride

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

29 September 2017

Selective oestrogen receptor modulation: molecular pharmacology for the millennium

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

29 September 2017

The interaction of raloxifene and the active metabolite of the antiestrogen EM-800 (SC 5705) with the human estrogen receptor.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

29 September 2017

The Effect of Raloxifene on Risk of Breast Cancer in Postmenopausal Women

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

29 September 2017

The oestrogen-like effect of 4-hydroxytamoxifen on induction of transforming growth factor alpha mRNA in MDA-MB-231 breast cancer cells stably expressing the oestrogen receptor

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

29 September 2017

Molecular determinants of tissue selectivity in estrogen receptor modulators

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

29 September 2017

A realistic clinical perspective of tamoxifen and endometrial carcinogenesis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

29 September 2017

Irreversible loss of the oestrogen receptor in T47D breast cancer cells following prolonged oestrogen deprivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

29 September 2017

p300 is a component of an estrogen receptor coactivator complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

29 September 2017

Ligand-dependent, transcriptionally productive association of the amino- and carboxyl-terminal regions of a steroid hormone nuclear receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

29 September 2017

Raloxifene (LY139481 HCI) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

29 September 2017

The estrogen receptor from a tamoxifen stimulated MCF-7 tumor variant contains a point mutation in the ligand binding domain

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

29 September 2017

Aspartate 351 of estrogen receptor alpha is not crucial for the antagonist activity of antiestrogens

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

2 June 2018

Chemoprevention of mammary carcinogenesis in the rat: combined use of raloxifene and 9-cis-retinoic acid.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

2 June 2018

Characterization of tamoxifen stimulated MCF-7 tumor variants grown in athymic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

2 June 2018

Indolo[3,2-b]carbazole: a dietary-derived factor that exhibits both antiestrogenic and estrogenic activity

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

2 June 2018

A naturally occurring estrogen receptor mutation results in increased estrogenicity of a tamoxifen analog

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

2 June 2018

Phase II Evaluation of Lyl56758 in Metastatic Breast Cancer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

2 June 2018

Development of tamoxifen-stimulated growth of MCF-7 tumors in athymic mice after long-term antiestrogen administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

2 June 2018

Growth regulation of estrogen receptor-negative breast cancer cells transfected with complementary DNAs for estrogen receptor

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

2 June 2018

A monohydroxylated metabolite of tamoxifen with potent antioestrogenic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

2 June 2018

Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators

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https://api.crossref.org/works/10.1074%2FJBC.M108335200

21 January 2018

Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108335200

21 January 2018

An antiestrogen-responsive estrogen receptor-alpha mutant (D351Y) shows weak AF-2 activity in the presence of tamoxifen

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108335200

21 January 2018

Nuclear receptor-binding sites of coactivators glucocorticoid receptor interacting protein 1 (GRIP1) and steroid receptor coactivator 1 (SRC-1): multiple motifs with different binding specificities

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https://api.crossref.org/works/10.1074%2FJBC.M108335200

21 January 2018

Estrogen response element binding induces alterations in estrogen receptor-alpha conformation as revealed by susceptibility to partial proteolysis

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https://api.crossref.org/works/10.1074%2FJBC.M108335200

21 January 2018

Molecular classification of estrogens.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

27 November 2018

Silencing and reactivation of the selective estrogen receptor modulator-estrogen receptor alpha complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

27 November 2018

Differences between estrogen- and antiestrogen-estrogen receptor complexes from human breast tumors identified with an antibody raised against the estrogen receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696956

27 November 2018

Antiestrogen basicity--activity relationships: a comparison of the estrogen receptor binding and antiuterotrophic potencies of several analogues of (Z)-1,2-diphenyl-1-[4-[2-(dimethylamino)ethoxy]phenyl]-1-butene (tamoxifen, Nolvadex) having altered

1 reference

https://pubmed.ncbi.nlm.nih.gov/11751902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Importance of the alkylaminoethoxy side-chain for the estrogenic and antiestrogenic actions of tamoxifen and trioxifene in the immature rat uterus

1 reference

https://pubmed.ncbi.nlm.nih.gov/11751902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antagonism of estrogen action with a new benzothiophene derived antiestrogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/11751902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An estrogen receptor model to describe the regulation of prolactin synthesis by antiestrogens in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/11751902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor actions of keoxifene and tamoxifen in the N-nitrosomethylurea-induced rat mammary carcinoma model

1 reference

https://pubmed.ncbi.nlm.nih.gov/11751902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of anti-estrogens on bone in castrated and intact female rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11751902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different residues of the human estrogen receptor are involved in the recognition of structurally diverse estrogens and antiestrogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/11751902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogenic activity is increased for an antiestrogen by a natural mutation of the estrogen receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11751902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The key to the antiestrogenic mechanism of raloxifene is amino acid 351 (aspartate) in the estrogen receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11751902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the estrogen receptor ligand binding domain discriminate between hormone-dependent transactivation and transrepression

1 reference

https://pubmed.ncbi.nlm.nih.gov/11751902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M108335200

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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