Mitochondrial redox metabolism in trypanosomatids is independent of tryparedoxin activity (Q28475438)

1 reference

GeneDB

5 February 2019

1 reference

GeneDB

6 February 2019

tryparedoxin 1b, putative

0 references

tryparedoxin 4, putative

0 references

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tryparedoxin 1a, putative

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tryparedoxin 4, putative

0 references

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tryparedoxin 2

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tryparedoxin 1

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tryparedoxin 3

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tryparedoxin 4, putative

0 references

Trypanosomatidae

object named as

trypanosomatids

1 reference

Sandra Carvalho

3

0 references

Helena Castro

object named as

Helena Castro

1

0 references

Ana M. Tomás

object named as

Ana M Tomás

6

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author name string

Susana Romao

2

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Filipa Teixeira

4

0 references

Carla Sousa

Creative Commons Attribution 4.0 International

5

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language of work or name

English

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publication date

8 September 2010

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published in

PLOS One

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volume

5

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issue

9

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page(s)

e12607

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copyright license

start time

8 September 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Structure of a trypanosomatid mitochondrial cytochrome c with heme attached via only one thioether bond and implications for the substrate recognition requirements of heme lyase

1 reference

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Structural Basis for a Distinct Catalytic Mechanism in Trypanosoma brucei Tryparedoxin Peroxidase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935891

Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935891

MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0

19 March 2017

1 reference

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Structures of tryparedoxins revealing interaction with trypanothione

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935891

Physiological functions of thioredoxin and thioredoxin reductase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935891

Cysteine residues exposed on protein surfaces are the dominant intramitochondrial thiol and may protect against oxidative damage

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935891

Enzymatic mechanism controls redox-mediated protein-DNA interactions at the replication origin of kinetoplast DNA minicircles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935891

The multiple functions of the thiol-based electron flow pathways of Escherichia coli: Eternal concepts revisited

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935891

Mitochondrial origin-binding protein UMSBP mediates DNA replication and segregation in trypanosomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935891

Glutathionylation of trypanosomal thiol redox proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935891

Depletion of the thioredoxin homologue tryparedoxin impairs antioxidative defence in African trypanosomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935891

BCL-2 in the crosshairs: tipping the balance of life and death

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935891

Overexpression of a cytochrome b5 reductase-like protein causes kinetoplast DNA loss in Trypanosoma brucei

29 September 2017

1 reference

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Expression of a mitochondrial peroxiredoxin prevents programmed cell death in Leishmania donovani

29 September 2017

1 reference

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ERp29, an unusual redox-inactive member of the thioredoxin family

29 September 2017

1 reference

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Emerging functions of mammalian mitochondrial fusion and fission

29 September 2017

1 reference

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Mitochondrial import and the twin-pore translocase

29 September 2017

1 reference

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Redox potential regulates binding of universal minicircle sequence binding protein at the kinetoplast DNA replication origin

29 September 2017

1 reference

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The tale of tail-anchored proteins: coming from the cytosol and looking for a membrane.

29 September 2017

1 reference

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RNA interference identifies two hydroperoxide metabolizing enzymes that are essential to the bloodstream form of the african trypanosome.

29 September 2017

1 reference

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Kinetics and Redox-Sensitive Oligomerisation Reveal Negative Subunit Cooperativity in Tryparedoxin Peroxidase of Trypanosoma brucei brucei

29 September 2017

1 reference

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The Role of Glutathione Peroxidases in Trypanosomatids

29 September 2017

1 reference

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The Trypanosoma cruzi enzyme TcGPXI is a glycosomal peroxidase and can be linked to trypanothione reduction by glutathione or tryparedoxin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935891

Trypanothione-dependent synthesis of deoxyribonucleotides by Trypanosoma brucei ribonucleotide reductase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935891

Distinct mitochondrial and cytosolic enzymes mediate trypanothione-dependent peroxide metabolism in Trypanosoma cruzi

29 September 2017

1 reference

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A unique cascade of oxidoreductases catalyses trypanothione-mediated peroxide metabolism in Crithidia fasciculata

29 September 2017

1 reference

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Culture microtitration: a sensitive method for quantifying Leishmania infantum in tissues of infected mice

29 September 2017

1 reference

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A shuttle vector which facilitates the expression of transfected genes in Trypanosoma cruzi and Leishmania

29 September 2017

1 reference

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Thioredoxin catalyzes the reduction of insulin disulfides by dithiothreitol and dihydrolipoamide

29 September 2017

1 reference

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A comparative study of type I and type II tryparedoxin peroxidases in Leishmania major

29 September 2017

1 reference

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A second class of peroxidases linked to the trypanothione metabolism

2 June 2018

1 reference

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Cloning, functional analysis, and mitochondrial localization of Trypanosoma brucei monothiol glutaredoxin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012607

Two linked genes of Leishmania infantum encode tryparedoxins localised to cytosol and mitochondrion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012607

Molecular characterisation of mitochondrial and cytosolic trypanothione-dependent tryparedoxin peroxidases in Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012607

The cytosolic tryparedoxin of Leishmania infantum is essential for parasite survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012607

Monothiol glutaredoxin-1 is an essential iron-sulfur protein in the mitochondrion of African trypanosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012607

Substrate specificity, localization, and essential role of the glutathione peroxidase-type tryparedoxin peroxidases in Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012607

Specificity and kinetics of a mitochondrial peroxiredoxin of Leishmania infantum

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012607

Complementary antioxidant defense by cytoplasmic and mitochondrial peroxiredoxins in Leishmania infantum

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012607

Distinct overexpression of cytosolic and mitochondrial tryparedoxin peroxidases results in preferential detoxification of different oxidants in arsenite-resistant Leishmania amazonensis with and without DNA amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012607

Functional and physicochemical characterization of the thioredoxin system in Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012607

Trypanothione-dependent peroxide metabolism in Trypanosoma cruzi different stages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012607

Trypanosoma brucei and Trypanosoma cruzi tryparedoxin peroxidases catalytically detoxify peroxynitrite via oxidation of fast reacting thiols.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012607

Leishmania major ascorbate peroxidase overexpression protects cells against reactive oxygen species-mediated cardiolipin oxidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012607

Genetic nomenclature for Trypanosoma and Leishmania.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012607

Cytoplasmic localization of the trypanothione peroxidase system in Crithidia fasciculata

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20838623

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Transfection of Leishmania and Trypanosoma brucei by electroporation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20838623

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0012607

1 reference

ADS bibcode

2010PLoSO...512607C

0 references

1 reference

1 reference

PubMed publication ID

20838623

1 reference