Redox imbalance and mutagenesis in spleens of mice harboring a hypomorphic allele of Gpdx(a) encoding glucose 6-phosphate dehydrogenase (Q28513921)

25 January 2017

title

Redox imbalance and mutagenesis in spleens of mice harboring a hypomorphic allele of Gpdx(a) encoding glucose 6-phosphate dehydrogenase (English)

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Glucose-6-phosphate dehydrogenase X-linked

25 January 2017

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GOA release 2020-03-11

Catalase

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GOA release 2020-03-11

Glutathione peroxidase 1

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GOA release 2020-03-11

author name string

Klaus Felix

1

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25 January 2017

Lynne D. Rockwood

2

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25 January 2017

Walter Pretsch

3

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25 January 2017

Georg Wilhelm Bornkamm

4

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25 January 2017

Siegfried Janz

5

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25 January 2017

publication date

15 January 2003

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Free Radical Biology and Medicine

25 January 2017

published in

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25 January 2017

volume

34

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25 January 2017

issue

2

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25 January 2017

page(s)

226–232

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A new lease of life for an old enzyme

25 January 2017

cites work

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7 January 2021

Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress

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Enhanced glutathione levels and oxidoresistance mediated by increased glucose-6-phosphate dehydrogenase expression

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Mechanisms of protection of catalase by NADPH. Kinetics and stoichiometry

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Moderate G6PD deficiency increases mutation rates in the brain of mice

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Plasmid-based transgenic mouse model for studying in vivo mutations

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Genomic instability in mouse Burkitt lymphoma is dominated by illegitimate genetic recombinations, not point mutations

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Genetic variation of glucose-6-phosphate dehydrogenase: a catalog and future prospects

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Low catalase activity in xeroderma pigmentosum fibroblasts and SV40-transformed human cell lines is directly related to decreased intracellular levels of the cofactor, NADPH.

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Cytosolic NADP(+)-dependent isocitrate dehydrogenase status modulates oxidative damage to cells

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DNA repair mediated by endonuclease-independent LINE-1 retrotransposition

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Importance of glucose-6-phosphate dehydrogenase in the adaptive response to hydrogen peroxide in Saccharomyces cerevisiae.

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Glucose-6-phosphate dehydrogenase and the oxidative pentose phosphate cycle protect cells against apoptosis induced by low doses of ionizing radiation

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Dynamic regulation of metabolism and respiration by endogenously produced nitric oxide protects against oxidative stress

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Oxidation of cellular thiols by hydroxyethyldisulphide inhibits DNA double-strand-break rejoining in G6PD deficient mammalian cells

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An embryoprotective role for glucose-6-phosphate dehydrogenase in developmental oxidative stress and chemical teratogenesis

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Impaired production of nitric oxide, superoxide, and hydrogen peroxide in glucose 6-phosphate-dehydrogenase-deficient granulocytes

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Mutation in the glucose-6-phosphate dehydrogenase gene leads to inactivation of Ku DNA end binding during oxidative stress

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Importance of glucose-6-phosphate dehydrogenase activity for cell growth

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Hexose monophosphate shunt enzymes in lung tumors from normal and glucose-6-phosphate-dehydrogenase-deficient subjects

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Human glucose-6-phosphate dehydrogenase (G6PD) gene transforms NIH 3T3 cells and induces tumors in nude mice

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7 January 2021

On the origin of multiple mutations in human cancers

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7 January 2021

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Identifiers

DOI

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