Dual mechanisms of repression of E2F1 activity by the retinoblastoma gene product (Q28593274)

31 January 2017

title

Dual mechanisms of repression of E2F1 activity by the retinoblastoma gene product (English)

1 reference

E2F transcription factor 1

31 January 2017

main subject

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GOA release 2020-03-11

1 reference

E. Zacksenhaus

1

1 reference

31 January 2017

Z. Jiang

series ordinal

2

1 reference

31 January 2017

R. A. Phillips

series ordinal

3

1 reference

31 January 2017

B. L. Gallie

series ordinal

4

1 reference

31 January 2017

language of work or name

English

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publication date

1 November 1996

1 reference

31 January 2017

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31 January 2017

volume

15

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31 January 2017

issue

21

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31 January 2017

page(s)

5917–5927

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The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB

31 January 2017

cites work

1 reference

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Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation

17 March 2017

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Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins

17 March 2017

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The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E

17 March 2017

1 reference

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DP-1: a cell cycle-regulated and phosphorylated component of transcription factor DRTF1/E2F which is functionally important for recognition by pRb and the adenovirus E4 orf 6/7 protein

17 March 2017

1 reference

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E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo

17 March 2017

1 reference

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E2F-4, a new member of the E2F transcription factor family, interacts with p107

17 March 2017

1 reference

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The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

17 March 2017

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E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle

17 March 2017

1 reference

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Interaction between the retinoblastoma protein and the oncoprotein MDM2

17 March 2017

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E2F-5, a new E2F family member that interacts with p130 in vivo

17 March 2017

1 reference

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The retinoblastoma protein and cell cycle control

17 March 2017

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SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

17 March 2017

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Mechanisms of nuclear localization of the progesterone receptor: evidence for interaction between monomers

17 March 2017

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Cloning of cDNAs for cellular proteins that bind to the retinoblastoma gene product

17 March 2017

1 reference

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Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Retinoblastoma gene product activates expression of the human TGF-β2 gene through transcription factor ATF-2

17 March 2017

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Alternative forms of Max as enhancers or suppressors of Myc-ras cotransformation

17 March 2017

1 reference

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Inhibitors of mammalian G1 cyclin-dependent kinases

17 March 2017

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Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

G1 events and regulation of cell proliferation

7 April 2017

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The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

The E2F transcription factor is a cellular target for the RB protein

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Regulation of the Ets-related transcription factor Elf-1 by binding to the retinoblastoma protein

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Molecular cloning and characterization of the mouse RB1 promoter

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Unraveling the function of the retinoblastoma gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

A bipartite nuclear localization signal in the retinoblastoma gene product and its importance for biological activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

In vivo functional protein-protein interaction: nuclear targeted hsp90 shifts cytoplasmic steroid receptor mutants into the nucleus

29 September 2017

1 reference

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The retinoblastoma protein binds E2F residues required for activation in vivo and TBP binding in vitro

29 September 2017

1 reference

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HPV16 E7 oncoprotein deregulates B-myb expression: correlation with targeting of p107/E2F complexes

29 September 2017

1 reference

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Phosphorylation of E2F-1 modulates its interaction with the retinoblastoma gene product and the adenoviral E4 19 kDa protein

29 September 2017

1 reference

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Heterodimerization of the transcription factors E2F-1 and DP-1 is required for binding to the adenovirus E4 (ORF6/7) protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter

29 September 2017

1 reference

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The retinoblastoma tumor suppressor protein.

29 September 2017

1 reference

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The transcription factor E2F-1 is a downstream target of RB action

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

A polypeptide domain that specifies migration of nucleoplasmin into the nucleus

29 September 2017

1 reference

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Construction and characterization of an SV40 mutant defective in nuclear transport of T antigen.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Amino acid sequences that determine the nuclear localization of yeast histone 2B.

29 September 2017

1 reference

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Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor.

29 September 2017

1 reference

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The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor.

29 September 2017

1 reference

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A cellular protein that competes with SV40 T antigen for binding to the retinoblastoma gene product

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Retinoblastoma-repression of E2F-dependent transcription depends on the ability of the retinoblastoma protein to interact with E2F and is abrogated by the adenovirus E1A oncoprotein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Adenovirus E1a prevents the retinoblastoma gene product from repressing the activity of a cellular transcription factor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

A role for retinoblastoma protein in potentiating transcriptional activation by the glucocorticoid receptor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Mechanism of active transcriptional repression by the retinoblastoma protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Functional domains of the human glucocorticoid receptor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

The adenovirus EIIA enhancer. Analysis of regulatory sequences and changes in binding activity of ATF and EIIF following adenovirus infection

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Retinoblastoma protein switches the E2F site from positive to negative element

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Retinoblastoma Gene Mutations in Human Cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

Disruption of retinoblastoma protein function by coexpression of its C pocket fragment.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452360

The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element

27 November 2018

1 reference

12 December 2020

Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members

1 reference

12 December 2020

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

12 December 2020

E2F-1 functions in mice to promote apoptosis and suppress proliferation

1 reference

12 December 2020

Identifiers

PMC publication ID

452360

0 references

1 reference