Perinatal loss of Nkx2-5 results in rapid conduction and contraction defects (Q28593447)

31 January 2017

title

Perinatal loss of Nkx2-5 results in rapid conduction and contraction defects (English)

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31 January 2017

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GOA release 2020-03-11

Colin Sumners

10

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author name string

Laura E. Briggs

1

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31 January 2017

Morihiko Takeda

2

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31 January 2017

Adolfo E. Cuadra

3

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31 January 2017

Hiroko Wakimoto

4

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31 January 2017

Melissa H. Marks

5

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31 January 2017

Alexandra J. Walker

6

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31 January 2017

Tsugio Seki

7

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31 January 2017

Suk P. Oh

8

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31 January 2017

Jonathan T. Lu

9

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31 January 2017

Mohan K. Raizada

11

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31 January 2017

Nobuo Horikoshi

12

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31 January 2017

Ellen O. Weinberg

13

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31 January 2017

Kenji Yasui

14

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31 January 2017

Yasuhiro Ikeda

15

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31 January 2017

Kenneth R. Chien

16

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31 January 2017

Hideko Kasahara

17

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31 January 2017

publication date

12 September 2008

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31 January 2017

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31 January 2017

volume

103

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31 January 2017

issue

6

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31 January 2017

page(s)

580–590

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Identification of cardiac-specific myosin light chain kinase

31 January 2017

cites work

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Tissue distribution and subcellular localization of the cardiac sodium channel during mouse heart development

17 March 2017

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A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development

17 March 2017

1 reference

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Control of stress-dependent cardiac growth and gene expression by a microRNA

17 March 2017

1 reference

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Nkx2.5 cell-autonomous gene function is required for the postnatal formation of the peripheral ventricular conduction system

17 March 2017

1 reference

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Inherited conduction system abnormalities--one group of diseases, many genes

17 March 2017

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Sodium channel mutations and susceptibility to heart failure and atrial fibrillation

17 March 2017

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SCN5A mutation associated with dilated cardiomyopathy, conduction disorder, and arrhythmia

17 March 2017

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Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block

17 March 2017

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Modulation of cardiac growth and development by HOP, an unusual homeodomain protein

17 March 2017

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Hop is an unusual homeobox gene that modulates cardiac development

17 March 2017

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Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a

17 March 2017

1 reference

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Cardiac excitation-contraction coupling

17 March 2017

1 reference

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A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease

17 March 2017

1 reference

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Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways

17 March 2017

1 reference

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The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development

17 March 2017

1 reference

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Congenital heart disease caused by mutations in the transcription factor NKX2-5

17 March 2017

1 reference

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NK-2 homeobox genes and heart development

17 March 2017

1 reference

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The gene tinman is required for specification of the heart and visceral muscles in Drosophila

17 March 2017

1 reference

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Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5

17 March 2017

1 reference

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Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse

17 March 2017

1 reference

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Roles and regulation of the cardiac sodium channel Na v 1.5: recent insights from experimental studies.

7 April 2017

1 reference

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The promiscuous nature of the cardiac sodium current

29 September 2017

1 reference

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Regulation of Ca2+ and Na+ in normal and failing cardiac myocytes

29 September 2017

1 reference

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Pathophysiological significance of T-type Ca2+ channels: expression of T-type Ca2+ channels in fetal and diseased heart

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590500

Voltage-dependent calcium channels and cardiac pacemaker activity: from ionic currents to genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590500

Altered intracellular Ca2+ handling in heart failure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590500

Intracellular calcium release and cardiac disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590500

29 September 2017

Cardiac channelopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590500

Progressive atrioventricular conduction defects and heart failure in mice expressing a mutant Csx/Nkx2.5 homeoprotein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590500

SERCA pump level is a critical determinant of Ca(2+)homeostasis and cardiac contractility

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590500

Abnormalities of calcium cycling in the hypertrophied and failing heart

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590500

Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590500

Csx: a murine homeobox-containing gene specifically expressed in the developing heart

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590500

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590500

Biochemical analyses of eight NKX2.5 homeodomain missense mutations causing atrioventricular block and cardiac anomalies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590500

Sodium current in single myocardial mouse cells.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590500

Spatiotemporal pattern of commitment to slowed proliferation in the embryonic mouse heart indicates progressive differentiation of the cardiac conduction system.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590500

Temporally regulated and tissue-specific gene manipulations in the adult and embryonic heart using a tamoxifen-inducible Cre protein

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590500

Cardiac and extracardiac expression of Csx/Nkx2.5 homeodomain protein.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590500

Dilated cardiomyopathy is associated with reduced expression of the cardiac sodium channel Scn5a

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/18689573

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Electrophysiological properties of neonatal mouse cardiac myocytes in primary culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/18689573

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Familial congenital heart disease, progressive atrioventricular block and the cardiac homeobox transcription factor gene NKX2.5:

1 reference

https://pubmed.ncbi.nlm.nih.gov/18689573

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1161/CIRCRESAHA.108.171835

1 reference

1 reference

1 reference

1 reference