Vav guanine nucleotide exchange factor Dmel_CG7893 (Q29810733)

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Protein found in Drosophila melanogaster

Vav-PC
CG7893-PD
Vav ortholog
Vav-PD
Vav-PB
Vav-PA
Vav
CG7893-PC
CG7893-PB
CG7893 gene product from transcript CG7893-RB
Vav guanine nucleotide exchange factor
CG7893-PA

Language	Label	Description	Also known as
English	Vav guanine nucleotide exchange factor Dmel_CG7893	Protein found in Drosophila melanogaster	Vav-PC CG7893-PD Vav ortholog Vav-PD Vav-PB Vav-PA Vav CG7893-PC CG7893-PB CG7893 gene product from transcript CG7893-RB Vav guanine nucleotide exchange factor CG7893-PA

Statements

1 reference

25 May 2022

UniProt protein ID

SH3-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NHV9

Dbl homology (DH) domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NHV9

CH domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NHV9

PH-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NHV9

SH2 domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NHV9

pleckstrin homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Vav, PH domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Calponin homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Dbl homology (DH) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH3 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Vav, SH2 domain, invertebrate, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

cellular component

determination method

1 reference

7 November 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NHV9&geneProductId=UniProtKB:Q9NHV9

determination method

intracellular anatomical structure

determination method

1 reference

16 July 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NHV9&geneProductId=UniProtKB:Q9NHV9

determination method

determination method

1 reference

8 April 2019

DroVav, the Drosophila melanogaster homologue of the mammalian Vav proteins, serves as a signal transducer protein in the Rac and DER pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

biological process

compound eye morphogenesis

determination method

1 reference

8 April 2019

The vav oncogene antagonises EGFR signalling and regulates adherens junction dynamics during Drosophila eye development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

determination method

1 reference

8 April 2019

Phylogenetic conservation of the regulatory and functional properties of the Vav oncoprotein family.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

determination method

1 reference

8 April 2019

The guanine exchange factor vav controls axon growth and guidance during Drosophila development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

central nervous system development

determination method

1 reference

8 April 2019

The guanine exchange factor vav controls axon growth and guidance during Drosophila development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

open tracheal system development

determination method

1 reference

8 April 2019

Phylogenetic conservation of the regulatory and functional properties of the Vav oncoprotein family.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

myoblast fusion

determination method

1 reference

8 April 2019

Phylogenetic conservation of the regulatory and functional properties of the Vav oncoprotein family.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

determination method

1 reference

8 April 2019

Phylogenetic conservation of the regulatory and functional properties of the Vav oncoprotein family.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

actin cytoskeleton reorganization

determination method

1 reference

8 April 2019

Phylogenetic conservation of the regulatory and functional properties of the Vav oncoprotein family.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

melanotic encapsulation of foreign target

determination method

1 reference

8 April 2019

A directed miniscreen for genes involved in the Drosophila anti-parasitoid immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

regulation of Rho protein signal transduction

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

intracellular signal transduction

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

negative regulation of epidermal growth factor receptor signaling pathway

determination method

1 reference

8 April 2019

The vav oncogene antagonises EGFR signalling and regulates adherens junction dynamics during Drosophila eye development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

photoreceptor cell axon guidance

determination method

1 reference

8 April 2019

The guanine exchange factor vav controls axon growth and guidance during Drosophila development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

activation of GTPase activity

determination method

1 reference

8 April 2019

Phylogenetic conservation of the regulatory and functional properties of the Vav oncoprotein family.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

regulation of adherens junction organization

determination method

1 reference

8 April 2019

The vav oncogene antagonises EGFR signalling and regulates adherens junction dynamics during Drosophila eye development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

epidermal growth factor receptor signaling pathway

determination method

border follicle cell migration

determination method

1 reference

8 April 2019

GTP exchange factor Vav regulates guided cell migration by coupling guidance receptor signalling to local Rac activation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

vascular endothelial growth factor receptor signaling pathway

determination method

1 reference

8 April 2019

GTP exchange factor Vav regulates guided cell migration by coupling guidance receptor signalling to local Rac activation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

positive regulation of ERK1 and ERK2 cascade

determination method

1 reference

8 April 2019

DroVav, the Drosophila melanogaster homologue of the mammalian Vav proteins, serves as a signal transducer protein in the Rac and DER pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

positive regulation of actin cytoskeleton reorganization

determination method

1 reference

8 April 2019

DroVav, the Drosophila melanogaster homologue of the mammalian Vav proteins, serves as a signal transducer protein in the Rac and DER pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NHV9

determination method

Vav, SH2 domain, invertebrate

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NHV9

Dbl homology (DH) domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NHV9

pleckstrin homology domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NHV9

protein kinase C-like, phorbol ester/diacylglycerol-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NHV9

Calponin homology domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NHV9

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NHV9

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NHV9

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NHV9

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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