dabrafenib &#160; Béarla (Q3011604)

PubChem ^Béarla

PubChem CID ^Béarla

Dabrafenib (Béarla)

19 Deireadh Fómhair 2016

foirmle cheimiceach

C₂₃H₂₀F₃N₅O₂S₂

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

Dabrafenib (Béarla)

18 Samhain 2016

CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

Dabrafenib (Béarla)

18 Samhain 2016

active ingredient in ^Béarla

Tafinlar ^Béarla

1 reference

RxNorm ^Béarla

RxNorm ID ^Béarla

1425223

14 Feabhra 2018

World Health Organisation international non-proprietary name ^Béarla

dabrafenib (Béarla)

2 references

ChEBI ^Béarla

ChEBI ID ^Béarla

dabrafenib (Béarla)

19 Deireadh Fómhair 2016

foilsithe i

Recommended INN: List 67 ^Béarla

dáta foilsithe

2012

spriocghalar

non-small-cell lung carcinoma ^Béarla

1 reference

2 Deireadh Fómhair 2018

metastatic melanoma ^Béarla

1 reference

2 Deireadh Fómhair 2018

ailse chraicinn

1 reference

2 Deireadh Fómhair 2018

meileanóma

1 reference

2 Deireadh Fómhair 2018

significant drug interaction ^Béarla

crizotinib ^Béarla

side effect ^Béarla

bone marrow failure ^Béarla

1 reference

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

idelalisib ^Béarla

side effect ^Béarla

bone marrow failure ^Béarla

1 reference

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

crizotinib ^Béarla

side effect ^Béarla

long QT syndrome ^Béarla

1 reference

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

céataconasól

side effect ^Béarla

long QT syndrome ^Béarla

1 reference

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

voriconazole ^Béarla

side effect ^Béarla

long QT syndrome ^Béarla

1 reference

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

ritonavir ^Béarla

side effect ^Béarla

long QT syndrome ^Béarla

1 reference

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

clarithromycin ^Béarla

side effect ^Béarla

long QT syndrome ^Béarla

1 reference

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

fosphenytoin ^Béarla

side effect ^Béarla

long QT syndrome ^Béarla

1 reference

A reference set of clinically relevant adverse drug-drug interactions ^Béarla

physically interacts with ^Béarla

B-Raf proto-oncogene, serine/threonine kinase ^Béarla

ról an ábhair

enzyme inhibitor ^Béarla

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY ^Béarla

Guide to Pharmacology Ligand ID ^Béarla

6494

iompórtáilte ó thionscadal Vicipéide

17 Lúnasa 2016

pregnancy category ^Béarla

US pregnancy category D ^Béarla

1 reference

Vicipéid an Bhéarla

LiverTox likelihood score ^Béarla

LiverTox toxicity likelihood category E* ^Béarla

1 reference

LiverTox ^Béarla

https://www.ncbi.nlm.nih.gov/books/n/livertox/Dabrafenib

8 Aibreán 2021

URL tagartha

last update ^Béarla

28 Meitheamh 2018

ról an ábhair

protein kinase inhibitors ^Béarla

2 references

NDF-RT ^Béarla

NDF-RT ID ^Béarla

N0000187069

5 Márta 2018

Medical Subject Headings ^Béarla

MeSH descriptor ID ^Béarla

15 Márta 2018

1 reference

Medical Subject Headings ^Béarla

MeSH descriptor ID ^Béarla

C561627

InChI=1S/C23H20F3N5O2S2/c1-23(2,3)21-30-18(19(34-21)16-10-11-28-22(27)29-16)12-6-4-9-15(17(12)26)31-35(32,33)20-13(24)7-5-8-14(20)25/h4-11,31H,1-3H3,(H2,27,28,29)

15 Márta 2018

catagóir Commons

Dabrafenib

0 references

Identifiers

InChI

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

Dabrafenib (Béarla)

18 Samhain 2016

InChIKey ^Béarla

2 references

PubChem ^Béarla

PubChem CID ^Béarla

Dabrafenib (Béarla)

18 Samhain 2016

ChEBI release 2020-09-01 ^Béarla

uimhir CAS

1195765-45-7

2 references

UNII ^Béarla

dabrafenib (Béarla)

18 Samhain 2016

CAS Common Chemistry ^Béarla

https://commonchemistry.cas.org/detail?cas_rn=1195765-45-7

6 Aibreán 2021

URL tagartha

InChIKey ^Béarla

ChemSpider ID ^Béarla

25948204

1 reference

ChemSpider ^Béarla

ChemSpider ID ^Béarla

25948204

Dabrafenib (Béarla)

18 Samhain 2016

PubChem CID ^Béarla

2 references

PubChem ^Béarla

PubChem CID ^Béarla

Dabrafenib (Béarla)

18 Samhain 2016

InChIKey ^Béarla

Reaxys registry number ^Béarla

19689971

1 reference

ChEBI ^Béarla

ChEBI ID ^Béarla

dabrafenib (Béarla)

19 Deireadh Fómhair 2016

ChEBI ID ^Béarla

mapping relation type ^Béarla

meaitseáil chruinn

2 references

ChEMBL ^Béarla

ChEMBL ID ^Béarla

CHEMBL2028663

DABRAFENIB (Béarla)

18 Samhain 2016

InChI=1S/C23H20F3N5O2S2/c1-23(2,3)21-30-18(19(34-21)16-10-11-28-22(27)29-16)12-6-4-9-15(17(12)26)31-35(32,33)20-13(24)7-5-8-14(20)25/h4-11,31H,1-3H3,(H2,27,28,29)

International Chemical Identifier ^Béarla

InChI

ChEMBL ID ^Béarla

CHEMBL2028663

1 reference

ChEMBL ^Béarla

ChEMBL ID ^Béarla

CHEMBL2028663

DABRAFENIB (Béarla)

bunaithe ar chur chuige heorastúil

18 Samhain 2016

SureChEMBL ID ^Béarla

SCHEMBL806377

2 references

inferred from InChIKey ^Béarla

InChIKey ^Béarla

UniChem compound ID ^Béarla

23468438

1 reference

UniChem ^Béarla

DSSTox substance ID ^Béarla

DTXSID20152499

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard ^Béarla

InChIKey ^Béarla

DSSTOX compound identifier ^Béarla

DTXCID8074990

0 references

LiverTox ID ^Béarla

Dabrafenib

0 references

EC number ^Béarla

689-166-9

1 reference

ECHA Substance Infocard database ^Béarla

ECHA Substance Infocard ID ^Béarla

100.215.965

27 Nollaig 2018

N-{3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzene-1-sulfonamide (Béarla)

quotation ^Béarla

CAS no.: 1195765-45-7 (Béarla)

ECHA Substance Infocard ID ^Béarla

100.215.965

1 reference

ECHA Substance Infocard database ^Béarla

ECHA Substance Infocard ID ^Béarla

100.215.965

27 Nollaig 2018

N-{3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzene-1-sulfonamide (Béarla)

quotation ^Béarla

CAS no.: 1195765-45-7 (Béarla)

ATC code ^Béarla

L01XE23

1 reference

DrugBank ^Béarla

DrugBank ID ^Béarla

08912

https://mednet-communities.net/inn/db/ViewINN.aspx?i=9458

Dabrafenib (Béarla)

dáta foilsithe

17 Samhain 2015

World Health Organisation international non-proprietary name numeric ID ^Béarla

9458

1 reference

URL tagartha

Guide to Pharmacology Ligand ID ^Béarla

6494

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY ^Béarla

Guide to Pharmacology Ligand ID ^Béarla

6494

dabrafenib (Béarla)

18 Samhain 2016

MeSH descriptor ID ^Béarla

C561627

luaite mar

dabrafenib

1 reference

Medical Subject Headings ^Béarla

MeSH descriptor ID ^Béarla

C561627

14 Márta 2018

RxNorm ID ^Béarla

1424911

1 reference

UNII ^Béarla

dabrafenib (Béarla)

18 Samhain 2016

DrugBank ID ^Béarla

DB08912

1 reference

InChIKey ^Béarla

bunaithe ar chur chuige heorastúil

Human Metabolome Database ID ^Béarla

HMDB0250818

2 references

inferred from InChIKey ^Béarla

InChIKey ^Béarla

UNII ^Béarla

2 references

UNII ^Béarla

dabrafenib (Béarla)

18 Samhain 2016

InChIKey ^Béarla

MedlinePlus drug identifier ^Béarla

a613038

0 references

PatientsLikeMe treatment ID ^Béarla

dabrafenib

0 references

NDF-RT ID ^Béarla

N0000187069

1 reference

UNII ^Béarla

dabrafenib (Béarla)

18 Samhain 2016

Probes And Drugs ID ^Béarla

PD003542

0 references

DrugCentral ID ^Béarla

4801

1 reference

UniChem ^Béarla

KEGG ID ^Béarla

D10064

1 reference

ChEBI ^Béarla

ChEBI ID ^Béarla

dabrafenib (Béarla)

https://docs.openalex.org/download-snapshot/snapshot-data-format

19 Deireadh Fómhair 2016

PDB ligand ID ^Béarla

P06

0 references

Freebase ID ^Béarla

/m/0pcvk7y

0 references

Microsoft Academic ID ^Béarla

2778830669

0 references

OpenAlex ID ^Béarla

1 reference

26 Eanáir 2022

PDB structure ID ^Béarla

5CSW

1 reference

Protein Data Bank ^Béarla

PDB structure ID ^Béarla

5CSW

5CSW (Béarla)

19 Deireadh Fómhair 2016

4XV2

1 reference

Protein Data Bank ^Béarla

PDB structure ID ^Béarla

4XV2

4XV2 (Béarla)

19 Deireadh Fómhair 2016

5HIE

1 reference

Protein Data Bank ^Béarla

PDB structure ID ^Béarla

5HIE

5HIE (Béarla)

19 Deireadh Fómhair 2016

UMLS CUI ^Béarla

C3467876

1 reference

UNII ^Béarla

bunaithe ar chur chuige heorastúil

dabrafenib (Béarla)

18 Samhain 2016

1 reference

inferred by common MeSH mappings on source and on Wikidata ^Béarla

UMLS 2023 ^Béarla