Acid-induced membrane fusion by the hemagglutinin protein and its role in influenza virus biology. (Q30364511)

20 June 2017

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23 October 2022

Acid-induced membrane fusion by the hemagglutinin protein and its role in influenza virus biology. (English)

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20 June 2017

Charles J Russell

1

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20 June 2017

publication date

1 January 2014

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Current Topics in Microbiology and Immunology

20 June 2017

published in

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20 June 2017

23 October 2022

385

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20 June 2017

page(s)

93-116

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Structural Characterization of an Early Fusion Intermediate of Influenza Virus Hemagglutinin

20 June 2017

cites work

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12 December 2020

Intracellular and viral membrane fusion: a uniting mechanism.

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12 December 2020

Proteolytic activation of the influenza virus hemagglutinin: The structure of the cleavage site and the enzymes involved in cleavage

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12 December 2020

Stability of infectious influenza A viruses at low pH and at elevated temperature

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12 December 2020

Identification of ectopic anionic trypsin I in rat lungs potentiating pneumotropic virus infectivity and increased enzyme level after virus infection

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12 December 2020

Hemagglutinin Receptor Specificity and Structural Analyses of Respiratory Droplet-Transmissible H5N1 Viruses

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12 December 2020

The influenza virus enigma

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12 December 2020

Hemagglutinin activation of pathogenic avian influenza viruses of serotype H7 requires the protease recognition motif R-X-K/R-R

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12 December 2020

Mechanisms of acid and base secretion by the airway epithelium

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12 December 2020

Studies of the membrane fusion activities of fusion peptide mutants of influenza virus hemagglutinin

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12 December 2020

The Receptor-Binding Domain of Influenza Virus Hemagglutinin Produced in Escherichia coli Folds into Its Native, Immunogenic Structure

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12 December 2020

Influenza virus can enter and infect cells in the absence of clathrin-mediated endocytosis

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12 December 2020

Endocytosis of influenza viruses

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12 December 2020

The pH of activation of the hemagglutinin protein regulates H5N1 influenza virus replication and pathogenesis in mice

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12 December 2020

Mini-plasmin found in the epithelial cells of bronchioles triggers infection by broad-spectrum influenza A viruses and Sendai virus

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12 December 2020

Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution

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12 December 2020

Differential infectious entry of human influenza A/NWS/33 virus (H1N1) in mammalian kidney cells

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12 December 2020

Determination of baseline human nasal pH and the effect of intranasally administered buffers

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12 December 2020

Experimental evolution of human influenza virus H3 hemagglutinin in the mouse lung identifies adaptive regions in HA1 and HA2.

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12 December 2020

Changes in the hemagglutinin molecule of influenza type A (H3N2) virus associated with increased virulence for mice.

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12 December 2020

GPI-anchored influenza hemagglutinin induces hemifusion to both red blood cell and planar bilayer membranes

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12 December 2020

Protonation and stability of the globular domain of influenza virus hemagglutinin

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12 December 2020

Receptor binding by a ferret-transmissible H5 avian influenza virus

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12 December 2020

Glycolytic control of vacuolar-type ATPase activity: a mechanism to regulate influenza viral infection

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12 December 2020

Amino acid residues in the fusion peptide pocket regulate the pH of activation of the H5N1 influenza virus hemagglutinin protein.

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12 December 2020

Comparison of in vitro replication features of H7N3 influenza viruses from wild ducks and turkeys: potential implications for interspecies transmission

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12 December 2020

Bat-derived influenza hemagglutinin H17 does not bind canonical avian or human receptors and most likely uses a unique entry mechanism

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12 December 2020

Increased acid stability of the hemagglutinin protein enhances H5N1 influenza virus growth in the upper respiratory tract but is insufficient for transmission in ferrets

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12 December 2020

Avian influenza virus surveillance and wild birds: past and present

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12 December 2020

Influenza A virus entry into cells lacking sialylated N-glycans

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12 December 2020

Structure of the hemagglutinin precursor cleavage site, a determinant of influenza pathogenicity and the origin of the labile conformation

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12 December 2020

Regulation of endocytic pH by the Na+,K+-ATPase in living cells

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12 December 2020

A novel influenza A virus mitochondrial protein that induces cell death.

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12 December 2020

Influenza hemagglutinin and neuraminidase membrane glycoproteins

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12 December 2020

Mutations affecting the stability of the haemagglutinin molecule impair the immunogenicity of live attenuated H3N2 intranasal influenza vaccine candidates lacking NS1.

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12 December 2020

Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium

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12 December 2020

Amantadine selection of a mutant influenza virus containing an acid-stable hemagglutinin glycoprotein: evidence for virus-specific regulation of the pH of glycoprotein transport vesicles

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12 December 2020

Membrane structure and fusion-triggering conformational change of the fusion domain from influenza hemagglutinin

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12 December 2020

Assembly of endocytic machinery around individual influenza viruses during viral entry

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12 December 2020

Single amino acid substitutions in influenza haemagglutinin change receptor binding specificity

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12 December 2020

The pathogenesis of influenza virus infections: the contributions of virus and host factors

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12 December 2020

Influenza virus A pathogenicity: the pivotal role of hemagglutinin

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12 December 2020

Altered receptor specificity and fusion activity of the haemagglutinin contribute to high virulence of a mouse-adapted influenza A virus

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12 December 2020

Deacylation of the hemagglutinin of influenza A/Aichi/2/68 has no effect on membrane fusion properties

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12 December 2020

Conformational changes in the hemagglutinin of influenza virus which accompany heat-induced fusion of virus with liposomes

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12 December 2020

Identification of a novel splice variant form of the influenza A virus M2 ion channel with an antigenically distinct ectodomain

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12 December 2020

Completion of trimeric hairpin formation of influenza virus hemagglutinin promotes fusion pore opening and enlargement

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12 December 2020

Adaptive mutation in influenza A virus non-structural gene is linked to host switching and induces a novel protein by alternative splicing

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12 December 2020

Proteolytic activation of the 1918 influenza virus hemagglutinin

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12 December 2020

Mutations in haemagglutinin that affect receptor binding and pH stability increase replication of a PR8 influenza virus with H5 HA in the upper respiratory tract of ferrets and may contribute to transmissibility

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12 December 2020

A complicated message: Identification of a novel PB1-related protein translated from influenza A virus segment 2 mRNA.

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12 December 2020

Structure of influenza haemagglutinin at neutral and at fusogenic pH by electron cryo-microscopy

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12 December 2020

Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation

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12 December 2020

Fluorescence assays to monitor fusion of enveloped viruses

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12 December 2020

Studies using double mutants of the conformational transitions in influenza hemagglutinin required for its membrane fusion activity

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12 December 2020

The genesis of a pandemic influenza virus.

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12 December 2020

Regulation of fusion activity by the cytoplasmic domain of a paramyxovirus F protein

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12 December 2020

Site-specific mutagenesis identifies three cysteine residues in the cytoplasmic tail as acylation sites of influenza virus hemagglutinin

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12 December 2020

Ducks: the "Trojan horses" of H5N1 influenza

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12 December 2020

Entry of influenza virus

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12 December 2020

H+-induced membrane insertion of influenza virus hemagglutinin involves the HA2 amino-terminal fusion peptide but not the coiled coil region

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12 December 2020

Lipid rafts and assembly of enveloped viruses

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12 December 2020

Mechanics of membrane fusion

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12 December 2020

Identification of novel influenza A virus proteins translated from PA mRNA

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12 December 2020

Influenza infection causes airway hyperresponsiveness by decreasing enkephalinase.

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12 December 2020

Leash in the groove mechanism of membrane fusion

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12 December 2020

Predicting 'airborne' influenza viruses: (trans-) mission impossible?

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12 December 2020

A spring-loaded mechanism for the conformational change of influenza hemagglutinin

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12 December 2020

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12 December 2020

Characterization of temperature sensitive influenza virus mutants defective in neuraminidase

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12 December 2020

Function, structure and regulation of the vacuolar (H+)-ATPases

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12 December 2020

Structure of the haemagglutinin-esterase-fusion glycoprotein of influenza C virus

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12 December 2020

Influenza hemagglutinin is spring-loaded by a metastable native conformation

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12 December 2020

Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an alternative entry pathway

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12 December 2020

Effect of Antibody to Neuraminidase on the Maturation and Hemagglutinating Activity of an Influenza A 2 Virus

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12 December 2020

N- and C-terminal residues combine in the fusion-pH influenza hemagglutinin HA(2) subunit to form an N cap that terminates the triple-stranded coiled coil

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12 December 2020

Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets

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12 December 2020

Airborne transmission of influenza A/H5N1 virus between ferrets

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12 December 2020

Influenza receptors, polymerase and host range.

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12 December 2020

Sequence relationships among the hemagglutinin genes of 12 subtypes of influenza A virus

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12 December 2020

Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease

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12 December 2020

Acid Stability of the Hemagglutinin Protein Regulates H5N1 Influenza Virus Pathogenicity

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12 December 2020

New world bats harbor diverse influenza A viruses

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12 December 2020

Structure of influenza haemagglutinin at the pH of membrane fusion

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12 December 2020

Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid

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12 December 2020

The pH of activation of the hemagglutinin protein regulates H5N1 influenza virus pathogenicity and transmissibility in ducks.

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12 December 2020

Early alterations of the receptor-binding properties of H1, H2, and H3 avian influenza virus hemagglutinins after their introduction into mammals

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12 December 2020

Single HA2 mutation increases the infectivity and immunogenicity of a live attenuated H5N1 intranasal influenza vaccine candidate lacking NS1.

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12 December 2020

An overlapping protein-coding region in influenza A virus segment 3 modulates the host response

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12 December 2020

Role of hemagglutinin cleavage for the pathogenicity of influenza virus.

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12 December 2020

Fatty acids on the A/Japan/305/57 influenza virus hemagglutinin have a role in membrane fusion.

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12 December 2020

The transmembrane domain of influenza hemagglutinin exhibits a stringent length requirement to support the hemifusion to fusion transition

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12 December 2020

HIV entry and its inhibition

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12 December 2020

Evidence that the transition of HIV-1 gp41 into a six-helix bundle, not the bundle configuration, induces membrane fusion

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12 December 2020

Mutations in the cytoplasmic tail of murine leukemia virus envelope protein suppress fusion inhibition by R peptide

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12 December 2020

Enhanced growth of influenza vaccine seed viruses in vero cells mediated by broadening the optimal pH range for virus membrane fusion

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12 December 2020

Adaptation of human influenza H3N2 virus in a mouse pneumonitis model: insights into viral virulence, tissue tropism and host pathogenesis.

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12 December 2020

Activation of a paramyxovirus fusion protein is modulated by inside-out signaling from the cytoplasmic tail

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12 December 2020

Analysis of residues near the fusion peptide in the influenza hemagglutinin structure for roles in triggering membrane fusion

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12 December 2020

Influenza virus M2 protein mediates ESCRT-independent membrane scission

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12 December 2020

Influenza HA subtypes demonstrate divergent phenotypes for cleavage activation and pH of fusion: implications for host range and adaptation

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12 December 2020

Influenza A virus transmission: contributing factors and clinical implications

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12 December 2020

Novel type II transmembrane serine proteases, MSPL and TMPRSS13, Proteolytically activate membrane fusion activity of the hemagglutinin of highly pathogenic avian influenza viruses and induce their multicycle replication

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12 December 2020

Functional balance between haemagglutinin and neuraminidase in influenza virus infections

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12 December 2020

Mechanisms of membrane fusion: disparate players and common principles.

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12 December 2020

Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin

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12 December 2020

Membrane fusion machines of paramyxoviruses: capture of intermediates of fusion

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12 December 2020

Lipid rafts as a membrane-organizing principle

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12 December 2020

Influenza virus assembly and budding in raft-derived microdomains: a quantitative analysis of the surface distribution of HA, NA and M2 proteins

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12 December 2020

Influenza hemagglutinins outside of the contact zone are necessary for fusion pore expansion

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12 December 2020

The structure of a membrane fusion mutant of the influenza virus haemagglutinin.

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12 December 2020

The function of the neuraminidase in membrane fusion induced by myxoviruses

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12 December 2020

Variant influenza virus hemagglutinin that induces fusion at elevated pH

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12 December 2020

Structure of influenza virus haemagglutinin complexed with a neutralizing antibody.

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12 December 2020

Isolation and characterization of a novel trypsin-like protease found in rat bronchiolar epithelial Clara cells. A possible activator of the viral fusion glycoprotein

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12 December 2020

Enhancement of the influenza A hemagglutinin (HA)-mediated cell-cell fusion and virus entry by the viral neuraminidase (NA).

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12 December 2020

Ligands for clathrin-mediated endocytosis are differentially sorted into distinct populations of early endosomes

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12 December 2020

Molecular determinants within the surface proteins involved in the pathogenicity of H5N1 influenza viruses in chickens

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12 December 2020

Fusion mutants of the influenza virus hemagglutinin glycoprotein

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12 December 2020

Folding, trimerization, and transport are sequential events in the biogenesis of influenza virus hemagglutinin

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12 December 2020

The cell biology of receptor-mediated virus entry

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12 December 2020

Adaptation of Egg-Grown and Transfectant Influenza Viruses for Growth in Mammalian Cells: Selection of Hemagglutinin Mutants with Elevated pH of Membrane Fusion

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12 December 2020

Acidification of the endocytic and exocytic pathways

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12 December 2020

Early steps of the conformational change of influenza virus hemagglutinin to a fusion active state: stability and energetics of the hemagglutinin

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12 December 2020

H5 avian and H9 swine influenza virus haemagglutinin structures: possible origin of influenza subtypes

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12 December 2020

Acid secretion and proton conductance in human airway epithelium

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12 December 2020

Influenza virus entry and infection require host cell N-linked glycoprotein

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12 December 2020

Glucose trimming and reglucosylation determine glycoprotein association with calnexin in the endoplasmic reticulum

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12 December 2020

An airborne transmissible avian influenza H5 hemagglutinin seen at the atomic level

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12 December 2020

Contribution of H7 haemagglutinin to amantadine resistance and infectivity of influenza virus

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12 December 2020

A distinct lineage of influenza A virus from bats

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12 December 2020

Influenza virus hemagglutinin concentrates in lipid raft microdomains for efficient viral fusion

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12 December 2020

Recombinant influenza A H3N2 viruses with mutations of HA transmembrane cysteines exhibited altered virological characteristics.

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12 December 2020

Comparison of complete amino acid sequences and receptor-binding properties among 13 serotypes of hemagglutinins of influenza A viruses

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12 December 2020

Influenza virus assembly and budding

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12 December 2020

A single amino acid in the stalk region of the H1N1pdm influenza virus HA protein affects viral fusion, stability and infectivity.

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12 December 2020

Identifiers

DOI

10.1007/82_2014_393

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20 June 2017

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