The GABA(A) receptor agonist THIP ameliorates specific behavioral deficits in the mouse model of fragile X syndrome (Q30461456)

18 September 2017

The GABA(A) receptor agonist THIP ameliorates specific behavioral deficits in the mouse model of fragile X syndrome (English)

1 reference

18 September 2017

1 reference

Jose Luis Olmos-Serrano

series ordinal

1

1 reference

18 September 2017

Joshua G Corbin

series ordinal

2

1 reference

18 September 2017

Mark P Burns

series ordinal

3

1 reference

18 September 2017

language of work or name

1 reference

8 November 2011

1 reference

Developmental Neuroscience

18 September 2017

1 reference

18 September 2017

33

1 reference

18 September 2017

5

1 reference

18 September 2017

395-403

1 reference

Methylphenidate enhances inhibitory synaptic transmission by increasing the content of norepinephrine in the locus coeruleus of juvenile rats

18 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Ambient GABA-activated tonic inhibition sharpens auditory coincidence detection via a depolarizing shunting mechanism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Extrasynaptic GABA(A) receptors and tonic inhibition in rat auditory thalamus.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Defective GABAergic neurotransmission and pharmacological rescue of neuronal hyperexcitability in the amygdala in a mouse model of fragile X syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Delayed stabilization of dendritic spines in fragile X mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Lithium ameliorates phenotypic deficits in a mouse model of fragile X syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

A role of GABA analogues in the treatment of neurological diseases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Amygdala inhibitory circuits and the control of fear memory

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Altered hippocampal synaptic plasticity in the FMR1 gene family knockout mouse models

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

The FXG: a presynaptic fragile X granule expressed in a subset of developing brain circuits

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Advances in the treatment of fragile X syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Downregulation of tonic GABAergic inhibition in a mouse model of fragile X syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Prepulse inhibition in fragile X syndrome: feasibility, reliability, and implications for treatment

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

The fragile X continuum: new advances and perspectives

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Evidence for social anxiety and impaired social cognition in a mouse model of fragile X syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Correction of fragile X syndrome in mice.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

The GABAA receptor: a novel target for treatment of fragile X?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

GABAA receptors as targets for novel anxiolytic drugs

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Local functions for FMRP in axon growth cone motility and activity-dependent regulation of filopodia and spine synapses

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Deficits in trace fear memory and long-term potentiation in a mouse model for fragile X syndrome.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Ovarian cycle-linked changes in GABA(A) receptors mediating tonic inhibition alter seizure susceptibility and anxiety

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Annotation: Deconstructing the attention deficit in fragile X syndrome: a developmental neuropsychological approach

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Tonically active GABA A receptors: modulating gain and maintaining the tone.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Sensorimotor gating abnormalities in young males with fragile X syndrome and Fmr1-knockout mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Behavioral and neuroanatomical characterization of the Fmr1 knockout mouse

20 June 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

20 June 2018

Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Abnormal striatal GABA transmission in the mouse model for the fragile X syndrome.

20 June 2018

1 reference

Decreased expression of the GABAA receptor in fragile X syndrome

21 January 2018

1 reference

Decreased GABA(A) receptor expression in the seizure-prone fragile X mouse.

21 January 2018

1 reference

The main source of ambient GABA responsible for tonic inhibition in the mouse hippocampus.

21 January 2018

1 reference

Fragile X mouse: strain effects of knockout phenotype and evidence suggesting deficient amygdala function.

21 January 2018

1 reference

Alterations in the auditory startle response in Fmr1 targeted mutant mouse models of fragile X syndrome

21 January 2018

1 reference

Fragile X mice develop sensory hyperreactivity to auditory stimuli

21 January 2018

1 reference

RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice

21 January 2018

1 reference

A phenotypic and molecular characterization of the fmr1-tm1Cgr fragile X mouse.

21 January 2018

1 reference

Numerous GABAergic afferents to locus ceruleus in the pericerulear dendritic zone: possible interneuronal pool.

21 January 2018

1 reference

Spatial learning, contextual fear conditioning and conditioned emotional response in Fmr1 knockout mice.

21 January 2018

1 reference

A functional role for dopamine transmission in the amygdala during conditioned fear

21 January 2018

1 reference

Evidence that GABA transmission mediates context-specific extinction of learned fear.

21 January 2018

1 reference

Reduced ventral anterior cingulate and amygdala volumes in medication-naïve females with major depressive disorder: A voxel-based morphometric magnetic resonance imaging study.

21 January 2018

1 reference

Auditory evoked magnetic fields in adults with fragile X syndrome.

21 January 2018

1 reference

Fmrp is required for the establishment of the startle response during the critical period of auditory development.

21 January 2018

1 reference

Involvement of pallidotegmental neurons in methamphetamine- and MK-801-induced impairment of prepulse inhibition of the acoustic startle reflex in mice: reversal by GABAB receptor agonist baclofen

21 January 2018

1 reference

Activation of GABA(B) receptors reverses spontaneous gating deficits in juvenile DBA/2J mice

21 January 2018

1 reference

Taurine improves congestive functions in a mouse model of fragile X syndrome

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

[A neuropsychological and behavioural profile of attention deficits in fragile X syndrome]

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Electrodermal responses to sensory stimuli in individuals with fragile X syndrome: a preliminary report.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254038

Prevalence of fragile X syndrome

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22067669

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1159/000332884

1 reference

18 September 2017

1 reference

18 September 2017

PubMed publication ID

22067669

1 reference