Cryo-electron tomography of motile cilia and flagella (Q30619433)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25646146%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Cryo-electron tomography of motile cilia and flagella (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25646146%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

1

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29 February 2020

author name string

Takashi Ishikawa

series ordinal

1

1 reference

19 October 2017

2 February 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25646146%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25646146%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

volume

4

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29 February 2020

issue

1

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29 February 2020

page(s)

3

1 reference

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Creative Commons Attribution 4.0 International

29 February 2020

copyright license

start time

2 February 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Loss-of-function mutations in RSPH1 cause primary ciliary dyskinesia with central-complex and radial-spoke defects

20 June 2018

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Centrosomal protein CEP104 (Chlamydomonas FAP256) moves to the ciliary tip during ciliary assembly

20 June 2018

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Novel structural labeling method using cryo-electron tomography and biotin-streptavidin system.

20 June 2018

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Isolation of intraflagellar transport trains.

20 June 2018

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Founder mutation in RSPH4A identified in patients of Hispanic descent with primary ciliary dyskinesia

20 June 2018

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Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM.

20 June 2018

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The MIA complex is a conserved and novel dynein regulator essential for normal ciliary motility

20 June 2018

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3D structural analysis of flagella/cilia by cryo-electron tomography.

20 June 2018

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The N-DRC forms a conserved biochemical complex that maintains outer doublet alignment and limits microtubule sliding in motile axonemes

20 June 2018

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The nexin-dynein regulatory complex subunit DRC1 is essential for motile cilia function in algae and humans

20 June 2018

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Conserved structural motifs in the central pair complex of eukaryotic flagella.

20 June 2018

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Mutations in CCDC39 and CCDC40 are the major cause of primary ciliary dyskinesia with axonemal disorganization and absent inner dynein arms

20 June 2018

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The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5

20 June 2018

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One of the nine doublet microtubules of eukaryotic flagella exhibits unique and partially conserved structures

20 June 2018

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Structural Basis for Microtubule Binding and Release by Dynein

20 June 2018

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Polarity and asymmetry in the arrangement of dynein and related structures in the Chlamydomonas axoneme

20 June 2018

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ATP-driven remodeling of the linker domain in the dynein motor

20 June 2018

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Structure of the Rigor Actin-Tropomyosin-Myosin Complex

20 June 2018

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Cartwheel architecture of Trichonympha basal body

20 June 2018

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Axonemal radial spokes: 3D structure, function and assembly.

20 June 2018

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The CSC connects three major axonemal complexes involved in dynein regulation

20 June 2018

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Cryoelectron tomography reveals doublet-specific structures and unique interactions in the I1 dynein.

20 June 2018

1 reference

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CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms

20 June 2018

1 reference

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Insights into dynein motor domain function from a 3.3-Å crystal structure

20 June 2018

1 reference

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Comparative structural analysis of eukaryotic flagella and cilia from Chlamydomonas, Tetrahymena, and sea urchins.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

The 2.8 Å crystal structure of the dynein motor domain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Cryo-electron tomography and 3-D analysis of the intact flagellum in Trypanosoma brucei.

20 June 2018

1 reference

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Three-dimensional structure of the Trypanosome flagellum suggests that the paraflagellar rod functions as a biomechanical spring

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Dynein achieves processive motion using both stochastic and coordinated stepping

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Designed ankyrin repeat proteins (DARPins) from research to therapy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

The structural heterogeneity of radial spokes in cilia and flagella is conserved

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Three-dimensional structure of basal body triplet revealed by electron cryo-tomography

20 June 2018

1 reference

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Cytoplasmic dynein moves through uncoordinated stepping of the AAA+ ring domains

20 June 2018

1 reference

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Zernike phase contrast cryo-electron tomography of whole mounted frozen cells

20 June 2018

1 reference

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Three-dimensional structure of the radial spokes reveals heterogeneity and interactions with dyneins in Chlamydomonas flagella

20 June 2018

1 reference

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Cryoelectron tomography of radial spokes in cilia and flagella.

20 June 2018

1 reference

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Cryo-electron tomography reveals conserved features of doublet microtubules in flagella

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Building blocks of the nexin-dynein regulatory complex in Chlamydomonas flagella.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Sequential assembly of flagellar radial spokes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Structure of Trypanosoma brucei flagellum accounts for its bihelical motion

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

The CSC is required for complete radial spoke assembly and wild-type ciliary motility

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Subunit interactions within the Chlamydomonas flagellar spokehead

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Structural Basis of the 9-Fold Symmetry of Centrioles

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Structures of SAS-6 suggest its organization in centrioles

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Three-dimensional structural analysis of eukaryotic flagella/cilia by electron cryo-tomography

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Automated data collection for electron microscopic tomography

20 June 2018

1 reference

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Nucleotide-induced global conformational changes of flagellar dynein arms revealed by in situ analysis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Procentriole assembly revealed by cryo-electron tomography

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

An atomic-level mechanism for activation of the kinesin molecular motors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

The dynein regulatory complex is the nexin link and a major regulatory node in cilia and flagella

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Electron-tomographic analysis of intraflagellar transport particle trains in situ

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Asymmetry of inner dynein arms and inter-doublet links in Chlamydomonas flagella

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Structural basis for the activation of muscle contraction by troponin and tropomyosin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Structure and Functional Role of Dynein's Microtubule-Binding Domain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Molecular architecture of inner dynein arms in situ in Chlamydomonas reinhardtii flagella.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Cryo-electron tomography of cells: connecting structure and function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Three-dimensional structure of cytoplasmic dynein bound to microtubules

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

A conserved CaM- and radial spoke associated complex mediates regulation of flagellar dynein activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Three-dimensional structures of the flagellar dynein-microtubule complex by cryoelectron microscopy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

The architecture of outer dynein arms in situ

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Radial spoke proteins of Chlamydomonas flagella

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

3D structure of eukaryotic flagella in a quiescent state revealed by cryo-electron tomography

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Automated electron microscope tomography using robust prediction of specimen movements

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Structural basis for Ca2+-regulated muscle relaxation at interaction sites of troponin with actin and tropomyosin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Proteomic analysis of a eukaryotic cilium

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Structural studies by electron tomography: from cells to molecules

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Mislocalization of DNAH5 and DNAH9 in respiratory cells from patients with primary ciliary dyskinesia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Bend propagation drives central pair rotation in Chlamydomonas reinhardtii flagella

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Flagellar radial spokes contain a Ca2+-stimulated nucleoside diphosphate kinase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

A tektin homologue is decreased in chlamydomonas mutants lacking an axonemal inner-arm dynein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Flagellar radial spoke protein 2 is a calmodulin binding protein required for motility in Chlamydomonas reinhardtii

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Electron cryo-microscopy shows how strong binding of myosin to actin releases nucleotide

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Structural-functional relationships of the dynein, spokes, and central-pair projections predicted from an analysis of the forces acting within a flagellum

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Functional diversity of axonemal dyneins as studied in Chlamydomonas mutants

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Use of frozen-hydrated axonemes to assess imaging parameters and resolution limits in cryoelectron tomography

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Functional reconstitution of Chlamydomonas outer dynein arms from alpha-beta and gamma subunits: requirement of a third factor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Outer doublet heterogeneity reveals structural polarity related to beat direction in Chlamydomonas flagella

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

The structural basis of ciliary bend formation. Radial spoke positional changes accompanying microtubule sliding

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Localization of tektin filaments in microtubules of sea urchin sperm flagella by immunoelectron microscopy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Activation of the dynein adenosinetriphosphatase by microtubules

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Splitting the ciliary axoneme: implications for a "switch-point" model of dynein arm activity in ciliary motion

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Arrangement of inner dynein arms in wild-type and mutant flagella of Chlamydomonas

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Flagellar elongation and shortening in Chlamydomonas. III. structures attached to the tips of flagellar microtubules and their relationship to the directionality of flagellar microtubule assembly

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Effect of vanadate on gill cilia: Switching mechanism in ciliary beat

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Native architecture of the centriole proximal region reveals features underlying its 9-fold radial symmetry

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Analysis of ciliary assembly and function in planaria

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Identification of dyneins that localize exclusively to the proximal portion of Chlamydomonas flagella.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Dyneins across eukaryotes: a comparative genomic analysis

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Understanding microtubule organizing centers by comparing mutant and wild-type structures with electron tomography.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

The molecular architecture of axonemes revealed by cryoelectron tomography.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Three-dimensional reconstruction of axonemal outer dynein arms in situ by electron tomography.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Reconstruction of the projection periodicity and surface architecture of the flagellar central pair complex.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Dynein structure and power stroke.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Presteady state kinetic analysis of vanadate-induced inhibition of the dynein ATPase

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313461

Structures linking the tips of ciliary and flagellar microtubules to the membrane

25 November 2018

1 reference

12 December 2020

An axonemal dynein particularly important for flagellar movement at high viscosity. Implications from a new Chlamydomonas mutant deficient in the dynein heavy chain gene DHC9

1 reference

12 December 2020

The roles of noncatalytic ATP binding and ADP binding in the regulation of dynein motile activity in flagella

1 reference

12 December 2020

Ability of paralyzed flagella mutants of Chlamydomonas to move

1 reference

12 December 2020

Association between actin and light chains in Chlamydomonas flagellar inner-arm dyneins

1 reference

12 December 2020

Attachment of the cap to the central microtubules of Tetrahymena cilia

1 reference

12 December 2020

Heterogeneity of dynein structure implies coordinated suppression of dynein motor activity in the axoneme

1 reference

12 December 2020

Bioinformatic approaches to dynein heavy chain classification

1 reference

12 December 2020

Induction of temporary beating in paralyzed flagella of Chlamydomonas mutants by application of external force

1 reference

12 December 2020

1 reference

12 December 2020

10.1186/S13630-014-0012-7

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25646146%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25646146%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

25646146

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25646146%20AND%20SRC:MED&resulttype=core&format=json