IRAK-2 regulates IL-1-mediated pathogenic Th17 cell development in helminthic infection (Q31036486)

5 September 2017

IRAK-2 regulates IL-1-mediated pathogenic Th17 cell development in helminthic infection (English)

1 reference

5 September 2017

Patrick M Smith

1

1 reference

5 September 2017

Berri Jacque

2

1 reference

5 September 2017

James R Conner

3

1 reference

5 September 2017

Alexander Poltorak

4

1 reference

5 September 2017

Miguel J Stadecker

5

1 reference

5 September 2017

6 October 2011

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5 September 2017

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5 September 2017

7

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5 September 2017

10

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5 September 2017

e1002272

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Creative Commons Attribution 4.0 International

5 September 2017

start time

6 October 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

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Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

21 June 2018

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T-bet protects against exacerbation of schistosome egg-induced immunopathology by regulating Th17-mediated inflammation

21 June 2018

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Genetic control of severe egg-induced immunopathology and IL-17 production in murine schistosomiasis

21 June 2018

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The AP-1 transcription factor Batf controls T(H)17 differentiation

21 June 2018

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A mutation in Irak2c identifies IRAK-2 as a central component of the TLR regulatory network of wild-derived mice

21 June 2018

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IRAK4 kinase activity is required for Th17 differentiation and Th17-mediated disease

21 June 2018

1 reference

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Cutting edge: IL-23 receptor gfp reporter mice reveal distinct populations of IL-17-producing cells

21 June 2018

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Critical regulation of early Th17 cell differentiation by interleukin-1 signaling

21 June 2018

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IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation

21 June 2018

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Regulation and function of NF-kappaB transcription factors in the immune system

21 June 2018

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Immunological and inflammatory functions of the interleukin-1 family

21 June 2018

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Interleukin-1 receptor-associated kinase 2 is critical for lipopolysaccharide-mediated post-transcriptional control.

21 June 2018

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21 June 2018

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Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

21 June 2018

1 reference

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IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype

21 June 2018

1 reference

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Dendritic cell IL-23 and IL-1 production in response to schistosome eggs induces Th17 cells in a mouse strain prone to severe immunopathology

21 June 2018

1 reference

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Coinfection with the intestinal nematode Heligmosomoides polygyrus markedly reduces hepatic egg-induced immunopathology and proinflammatory cytokines in mouse models of severe schistosomiasis.

21 June 2018

1 reference

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TH17 cells in development: an updated view of their molecular identity and genetic programming

21 June 2018

1 reference

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The biological functions of T helper 17 cell effector cytokines in inflammation

21 June 2018

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Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor

21 June 2018

1 reference

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The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

21 June 2018

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Forward genetic analysis of Toll-like receptor responses in wild-derived mice reveals a novel antiinflammatory role for IRAK1BP1

21 June 2018

1 reference

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Protective immune mechanisms in helminth infection

21 June 2018

1 reference

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TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

21 June 2018

1 reference

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Development, cytokine profile and function of human interleukin 17-producing helper T cells

21 June 2018

1 reference

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Essential autocrine regulation by IL-21 in the generation of inflammatory T cells

21 June 2018

1 reference

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IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

21 June 2018

1 reference

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IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor-mediated immune responses but not in TCR signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

Differentiation and function of Th17 T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

The immune response to parasitic helminths: insights from murine models.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

Wild mice: an ever-increasing contribution to a popular mammalian model.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

The immunobiology of schistosomiasis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

Hyporesponsiveness of SPRET/Ei mice to lethal shock induced by tumor necrosis factor and implications for a TNF-based antitumor therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

Th1-polarizing immunization with egg antigens correlates with severe exacerbation of immunopathology and death in schistosome infection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

21 June 2018

Hepatic schistosomiasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

The impact of host genetics on susceptibility to human infectious diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

Delayed hypersensitivity-type granuloma formation and dermal reaction induced and elicited by a soluble factor isolated from Schistosoma mansoni eggs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

Variation of hepatic fibrosis and granuloma size among mouse strains infected with Schistosoma mansoni

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

A sequence-based variation map of 8.27 million SNPs in inbred mouse strains

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002272

Sequencing, expression, and functional analyses support the candidacy of Ncf2 in susceptibility to Salmonella typhimurium infection in wild-derived mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002272

RelA and RelB transcription factors in distinct thymocyte populations control lymphotoxin-dependent interleukin-17 production in γδ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002272

Crucial role for nuclear factor of activated T cells in T cell receptor-mediated regulation of human interleukin-17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002272

Severe CD4 T cell-mediated immunopathology in murine schistosomiasis is dependent on IL-12p40 and correlates with high levels of IL-17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002272

Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002272

Enhanced egg-induced immunopathology correlates with high IFN-gamma in murine schistosomiasis: identification of two epistatic genetic intervals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002272

Genetic localization of a locus controlling the intensity of infection by Schistosoma mansoni on chromosome 5q31–q33

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002272

A Critical Role for the Innate Immune Signaling Molecule IRAK-4 in T Cell Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002272

Genome search for additional human loci controlling infection levels by Schistosoma mansoni.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188523

The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4

25 November 2018

1 reference

12 December 2020

On the subspecific origin of the laboratory mouse

1 reference

12 December 2020

IL-23 is required for the development of severe egg-induced immunopathology in schistosomiasis and for lesional expression of IL-17

1 reference

12 December 2020

BATF: bringing (in) another Th17-regulating factor

1 reference

12 December 2020

Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice

1 reference

12 December 2020

Expression of class II, but not class I, major histocompatibility complex molecules is required for granuloma formation in infection with Schistosoma mansoni

1 reference

12 December 2020

10.1371/JOURNAL.PPAT.1002272

Identifiers

DOI

1 reference

release_qzb5p2ovknfajmqlwa7spwbvzq

5 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qzb5p2ovknfajmqlwa7spwbvzq

24 November 2022

mapped directly with Wikidata item

1 reference

5 September 2017

PubMed publication ID

21998578

1 reference