Interaction of antithrombin with sulfated, low molecular weight lignins: opportunities for potent, selective modulation of antithrombin function. (Q33460885)

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English	Interaction of antithrombin with sulfated, low molecular weight lignins: opportunities for potent, selective modulation of antithrombin function.	scientific article

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30 January 2020

Interaction of antithrombin with sulfated, low molecular weight lignins: opportunities for potent, selective modulation of antithrombin function (English)

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30 January 2020

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30 January 2020

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Brian L Henry

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30 January 2020

Justin Connell

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30 January 2020

Aiye Liang

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30 January 2020

Chandravel Krishnasamy

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4 June 2009

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30 January 2020

Journal of Biological Chemistry

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30 January 2020

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30 January 2020

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30 January 2020

20897-20908

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30 January 2020

Characterization of the plasma and blood anticoagulant potential of structurally and mechanistically novel oligomers of 4-hydroxycinnamic acids

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21 June 2018

Capillary electrophoretic study of small, highly sulfated, non-sugar molecules interacting with antithrombin.

1 reference

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21 June 2018

Characterization of a heparin-binding site on the catalytic domain of factor XIa: mechanism of heparin acceleration of factor XIa inhibition by the serpins antithrombin and C1-inhibitor

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21 June 2018

Outbreak of adverse reactions associated with contaminated heparin

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21 June 2018

On designing non-saccharide, allosteric activators of antithrombin.

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21 June 2018

Safety and efficacy of fondaparinux as an adjunctive treatment to thrombolysis in patients with high and intermediate risk pulmonary embolism

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21 June 2018

Recent research developments in the direct inhibition of coagulation proteinases--inhibitors of the initiation phase

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21 June 2018

Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events

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21 June 2018

Contaminated heparin associated with adverse clinical events and activation of the contact system

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21 June 2018

Fondaparinux sodium: a review of its use in the management of acute coronary syndromes

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21 June 2018

Characterization of the conformational alterations, reduced anticoagulant activity, and enhanced antiangiogenic activity of prelatent antithrombin

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21 June 2018

A novel allosteric pathway of thrombin inhibition: Exosite II mediated potent inhibition of thrombin by chemo-enzymatic, sulfated dehydropolymers of 4-hydroxycinnamic acids

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21 June 2018

Novel chemo-enzymatic oligomers of cinnamic acids as direct and indirect inhibitors of coagulation proteinases

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21 June 2018

Finding a needle in a haystack: development of a combinatorial virtual screening approach for identifying high specificity heparin/heparan sulfate sequence(s).

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21 June 2018

What does it take to make the perfect clot?

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21 June 2018

Importance of tryptophan 49 of antithrombin in heparin binding and conformational activation.

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21 June 2018

Mass spectrometry in the biosynthetic and structural investigation of lignins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742855

21 June 2018

Lignin biosynthesis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742855

21 June 2018

Heparin and calcium ions dramatically enhance antithrombin reactivity with factor IXa by generating new interaction exosites.

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21 June 2018

Capillary electrophoresis determination of the binding affinity of bioactive sulfated polysaccharides to proteins: study of the binding properties of fucoidan to antithrombin

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742855

21 June 2018

Heparin-protein interactions

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21 June 2018

Interaction of designed sulfated flavanoids with antithrombin: lessons on the design of organic activators.

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21 June 2018

Heparin and heparan sulfate: structure and function

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21 June 2018

Designing small, nonsugar activators of antithrombin using hydropathic interaction analyses.

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21 June 2018

Antithrombin binding of low molecular weight heparins and inhibition of factor Xa.

1 reference

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21 June 2018

Mechanism of heparin activation of antithrombin. Role of individual residues of the pentasaccharide activating sequence in the recognition of native and activated states of antithrombin.

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21 June 2018

The anticoagulant activation of antithrombin by heparin

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21 June 2018

Development and validation of a genetic algorithm for flexible docking

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21 June 2018

Binding of factor VIIa to tissue factor permits rapid antithrombin III/heparin inhibition of factor VIIa

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21 June 2018

Mechanism of acceleration of antithrombin-proteinase reactions by low affinity heparin. Role of the antithrombin binding pentasaccharide in heparin rate enhancement

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21 June 2018

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21 June 2018

Predominant contribution of surface approximation to the mechanism of heparin acceleration of the antithrombin-thrombin reaction. Elucidation from salt concentration effects.

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21 June 2018

Role of the antithrombin-binding pentasaccharide in heparin acceleration of antithrombin-proteinase reactions. Resolution of the antithrombin conformational change contribution to heparin rate enhancement

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21 June 2018

Exploring new non-sugar sulfated molecules as activators of antithrombin.

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21 January 2018

Antithrombin activation by nonsulfated, non-polysaccharide organic polymer

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Mechanism of poly(acrylic acid) acceleration of antithrombin inhibition of thrombin: implications for the design of novel heparin mimics.

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21 January 2018

Antiangiogenic forms of antithrombin specifically bind to the anticoagulant heparin sequence.

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Structure and anticoagulant activity of a sulfated galactan from the red alga, Gelidium crinale. Is there a specific structural requirement for the anticoagulant action?

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21 January 2018

Complex-dependent inhibition of factor VIIa by antithrombin III and heparin.

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31 October 2018

Determination of the binding parameters for antithrombin-heparin fragment systems by affinity and frontal analysis continuous capillary electrophoresis

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12 December 2020

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Nonspecific electrostatic binding characteristics of the heparin-antithrombin interaction

1 reference

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12 December 2020

based on heuristic

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Heparin and low-molecular-weight heparin

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sulfated galactan is a catalyst of antithrombin-mediated inactivation of alpha-thrombin

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12 December 2020

based on heuristic

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Effect of heparin on the inactivation rate of human activated factor XII by antithrombin III

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Importance of substrate composition, pH and other variables on tissue factor enhancement of factor VIIa activity

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thermodynamics of charged oligopeptide-heparin interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19497853

12 December 2020

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1 reference

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Accelerating ability of synthetic oligosaccharides on antithrombin inhibition of proteinases of the clotting and fibrinolytic systems. Comparison with heparin and low-molecular-weight heparin

1 reference

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12 December 2020

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10.1074/JBC.M109.013359

1 reference

Europe PubMed Central

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30 January 2020

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30 January 2020

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30 January 2020

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