Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans (Q33641648)

28 July 2017

2 references

12 October 2019

8 April 2021

Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans (English)

1 reference

28 July 2017

0 references

1 reference

12 October 2019

1 reference

8 April 2021

William J McCarty

4

0 references

Manjunath Hegde

object named as

Manjunath Hegde

5

0 references

Lawrence Vernetti

object named as

Lawrence Vernetti

10

0 references

Albert Gough

object named as

Albert Gough

11

0 references

author name string

Abhinav Bhushan

1

1 reference

28 July 2017

Nina Senutovitch

2

1 reference

28 July 2017

Shyam S Bale

3

1 reference

28 July 2017

Rohit Jindal

6

1 reference

28 July 2017

Inna Golberg

7

1 reference

28 July 2017

O Berk Usta

8

1 reference

28 July 2017

Martin L Yarmush

9

1 reference

28 July 2017

Ahmet Bakan

12

1 reference

28 July 2017

Tong Ying Shun

13

1 reference

28 July 2017

Richard DeBiasio

14

1 reference

28 July 2017

D Lansing Taylor

15

1 reference

28 July 2017

publication date

20 December 2013

3 references

Stem Cell Research & Therapy

28 July 2017

12 October 2019

8 April 2021

3 references

28 July 2017

12 October 2019

8 April 2021

4 Suppl 1

1 reference

28 July 2017

page(s)

S16

1 reference

Redesign of genetically encoded biosensors for monitoring mitochondrial redox status in a broad range of model eukaryotes.

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

Fluorescent biosensors - probing protein kinase function in cancer and drug discovery

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

Towards automated production and drug sensitivity testing using scaffold-free spherical tumor microtissues

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

Apoptosis as a Mechanism for Liver Disease Progression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

Early safety assessment using cellular systems biology yields insights into mechanisms of action

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

Amino acid-mediated heterotypic interaction governs performance of a hepatic tissue model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

Oxygen uptake rates and liver-specific functions of hepatocyte and 3T3 fibroblast co-cultures.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

Mechanisms of drug-induced liver injury.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

Microfabricated grooved substrates as platforms for bioartificial liver reactors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

Recognizing drug-induced liver injury: current problems, possible solutions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

First dose of potential new medicines to humans: how animals help

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

Poly(dimethylsiloxane) as a material for fabricating microfluidic devices

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

VEGF receptor 2 and the adherens junction as a mechanical transducer in vascular endothelial cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

Mechanisms of hepatotoxicity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

Concordance of the toxicity of pharmaceuticals in humans and in animals

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

Effect of cell-cell interactions in preservation of cellular phenotype: cocultivation of hepatocytes and nonparenchymal cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

Fluorescent Protein Biosensors: Measurement of Molecular Dynamics in Living Cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

Microscope laser light-scattering spectroscopy of vesicles within canaliculi of rat hepatocyte couplets

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028964

Cellular imaging predictions of clinical drug-induced liver injury

21 June 2018

1 reference

A long-term three dimensional liver co-culture system for improved prediction of clinically relevant drug-induced hepatotoxicity

21 January 2018

1 reference

Protective role of Kupffer cells in acetaminophen-induced hepatic injury in mice

21 January 2018

1 reference

Endothelium-mediated hepatocyte recruitment in the establishment of liver-like tissue in vitro.

21 January 2018

1 reference

Rat liver sinusoidal endothelial cells survive without exogenous VEGF in 3D perfused co-cultures with hepatocytes.

21 January 2018

1 reference

An artificial liver sinusoid with a microfluidic endothelial-like barrier for primary hepatocyte culture

21 January 2018

1 reference

Microfabrication of hepatocyte/fibroblast co-cultures: role of homotypic cell interactions

21 January 2018

1 reference

A thin-walled polydimethylsiloxane bioreactor for high-density hepatocyte sandwich culture

21 January 2018

1 reference

Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24565476

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Reagents to measure and manipulate cell functions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24565476

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/SCRT377

1 reference

Dimensions Publication ID

28 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/scrt377

9 September 2019

1 reference

28 July 2017

1 reference