Informatics Approach to the Rational Design of siRNA Libraries (Q33691748)

28 July 2017

title

Informatics approach to the rational design of siRNA libraries (English)

1 reference

28 July 2017

Informatics Approach to the Rational Design of siRNA Libraries (English)

1 reference

https://api.crossref.org/works/10.1007/978-1-60761-839-3_14

12 July 2024

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20838976

12 July 2024

author name string

Charles Jagun

2

1 reference

28 July 2017

Weifan Zheng

3

1 reference

28 July 2017

Jerry O. Ebalunode

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20838976

12 July 2024

language of work or name

English

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publication date

1 January 2011

1 reference

full work available at URL

28 July 2017

http://link.springer.com/content/pdf/10.1007/978-1-60761-839-3_14

1 reference

https://api.crossref.org/works/10.1007/978-1-60761-839-3_14

Methods in Molecular Biology

12 July 2024

published in

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28 July 2017

volume

672

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28 July 2017

page(s)

341-358

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

28 July 2017

cites work

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A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity

12 July 2024

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In silico selection of active siRNA.

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Predicting the efficacy of short oligonucleotides in antisense and RNAi experiments with boosted genetic programming.

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Design of a genome-wide siRNA library using an artificial neural network

12 July 2024

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Improved and automated prediction of effective siRNA.

12 July 2024

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Comparison of approaches for rational siRNA design leading to a new efficient and transparent method

12 July 2024

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A structural interpretation of the effect of GC-content on efficiency of RNA interference

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Efficient siRNA selection using hybridization thermodynamics

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Computational models with thermodynamic and composition features improve siRNA design

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Approximate Bayesian feature selection on a large meta-dataset offers novel insights on factors that effect siRNA potency

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Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

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Analysis of gene function in somatic mammalian cells using small interfering RNAs

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12 July 2024

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Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference

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Efficient prediction of siRNAs with siRNArules 1.0: an open-source JAVA approach to siRNA algorithms

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Asymmetry in the assembly of the RNAi enzyme complex

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Functional siRNAs and miRNAs Exhibit Strand Bias

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The gene-silencing efficiency of siRNA is strongly dependent on the local structure of mRNA at the targeted region

12 July 2024

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An accurate and interpretable model for siRNA efficacy prediction

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12 July 2024

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12 July 2024

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Demonstration of two novel methods for predicting functional siRNA efficiency

12 July 2024

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RFRCDB-siRNA: improved design of siRNAs by random forest regression model coupled with database searching

12 July 2024

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siRNA Selection Server: an automated siRNA oligonucleotide prediction server

12 July 2024

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siVirus: web-based antiviral siRNA design software for highly divergent viral sequences

12 July 2024

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OligoWalk: an online siRNA design tool utilizing hybridization thermodynamics

12 July 2024

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AsiDesigner: exon-based siRNA design server considering alternative splicing

12 July 2024

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New chemical descriptors relevant for the design of biologically active peptides. A multivariate characterization of 87 amino acids

12 July 2024

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Quantitative sequence-activity models (QSAM)--tools for sequence design

12 July 2024

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12 July 2024

Identifiers

1 reference

28 July 2017

1 reference