Development of selective inhibitors for human aldehyde dehydrogenase 3A1 (ALDH3A1) for the enhancement of cyclophosphamide cytotoxicity. (Q33707099)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24677340%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

Development of selective inhibitors for human aldehyde dehydrogenase 3A1 (ALDH3A1) for the enhancement of cyclophosphamide cytotoxicity (English)

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12 March 2020

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3

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12 March 2020

author name string

Bibek Parajuli

series ordinal

1

1 reference

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12 March 2020

Taxiarchis M Georgiadis

series ordinal

2

1 reference

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12 March 2020

Thomas D Hurley

series ordinal

4

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12 March 2020

language of work or name

English

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publication date

1 March 2014

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12 March 2020

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12 March 2020

volume

15

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12 March 2020

issue

5

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12 March 2020

page(s)

701-712

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Aldehyde dehydrogenases and cell proliferation.

12 March 2020

cites work

1 reference

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Discovery of a Novel Class of Covalent Inhibitor for Aldehyde Dehydrogenases

21 June 2018

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Aldehyde dehydrogenase: its role as a cancer stem cell marker comes down to the specific isoform

21 June 2018

1 reference

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Discovery of novel regulators of aldehyde dehydrogenase isoenzymes

21 June 2018

1 reference

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Inhibition of aldehyde dehydrogenase-2 suppresses cocaine seeking by generating THP, a cocaine use-dependent inhibitor of dopamine synthesis.

21 June 2018

1 reference

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Activation of aldehyde dehydrogenase 2 (ALDH2) confers cardioprotection in protein kinase C epsilon (PKCvarepsilon) knockout mice

21 June 2018

1 reference

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Cyclophosphamide and cancer: golden anniversary

21 June 2018

1 reference

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MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer

21 June 2018

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Aldehyde dehydrogenase as a marker for stem cells

21 June 2018

1 reference

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ALDH isozymes downregulation affects cell growth, cell motility and gene expression in lung cancer cells

21 June 2018

1 reference

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Time-dependent and ethanol-induced cardiac protection from ischemia mediated by mitochondrial translocation of varepsilonPKC and activation of aldehyde dehydrogenase 2.

21 June 2018

1 reference

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Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart

21 June 2018

1 reference

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Structure of daidzin, a naturally occurring anti-alcohol-addiction agent, in complex with human mitochondrial aldehyde dehydrogenase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4043872

Multiple and additive functions of ALDH3A1 and ALDH1A1: cataract phenotype and ocular oxidative damage in Aldh3a1(-/-)/Aldh1a1(-/-) knock-out mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4043872

Structural and Functional Consequences of Coenzyme Binding to the Inactive Asian Variant of Mitochondrial Aldehyde Dehydrogenase: ROLES OF RESIDUES 475 AND 487

21 June 2018

1 reference

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HKL-3000: the integration of data reduction and structure solution--from diffraction images to an initial model in minutes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4043872

RNAi-mediated knockdown of aldehyde dehydrogenase class-1A1 and class-3A1 is specific and reveals that each contributes equally to the resistance against 4-hydroperoxycyclophosphamide

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4043872

An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4043872

Analysis and update of the human aldehyde dehydrogenase (ALDH) gene family

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4043872

Coot: model-building tools for molecular graphics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4043872

Coenzyme isomerization is integral to catalysis in aldehyde dehydrogenase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4043872

Identification of the enzymatic mechanism of nitroglycerin bioactivation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4043872

Cellular levels of aldehyde dehydrogenases (ALDH1A1 and ALDH3A1) as predictors of therapeutic responses to cyclophosphamide-based chemotherapy of breast cancer: a retrospective study. Rational individualization of oxazaphosphorine-based cancer chemo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4043872

Inactivation of aldophosphamide by human aldehyde dehydrogenase isozyme 3.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4043872

Aldehyde dehydrogenase-mediated cellular relative insensitivity to the oxazaphosphorines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4043872

Mutations in the Delta1-pyrroline 5-carboxylate dehydrogenase gene cause type II hyperprolinemia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4043872

Inhibition of human class 3 aldehyde dehydrogenase, and sensitization of tumor cells that express significant amounts of this enzyme to oxazaphosphorines, by chlorpropamide analogues

21 June 2018

1 reference

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Constitutive expression of class 3 aldehyde dehydrogenase in cultured rat corneal epithelium

21 June 2018

1 reference

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Sjögren-Larsson syndrome is caused by mutations in the fatty aldehyde dehydrogenase gene

21 June 2018

1 reference

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Identification and characterization of a novel class 3 aldehyde dehydrogenase overexpressed in a human breast adenocarcinoma cell line exhibiting oxazaphosphorine-specific acquired resistance

21 June 2018

1 reference

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Intrinsic cellular resistance to oxazaphosphorines exhibited by a human colon carcinoma cell line expressing relatively large amounts of a class-3 aldehyde dehydrogenase

21 June 2018

1 reference

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Type II hyperprolinemia. Delta1-pyrroline-5-carboxylic acid dehydrogenase deficiency in cultured skin fibroblasts and circulating lymphocytes

21 June 2018

1 reference

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Phenolic antioxidant-induced overexpression of class-3 aldehyde dehydrogenase and oxazaphosphorine-specific resistance.

21 June 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300625

Retinoic acid down-regulates aldehyde dehydrogenase and increases cytotoxicity of 4-hydroperoxycyclophosphamide and acetaldehyde

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300625

Multiple conformations of NAD and NADH when bound to human cytosolic and mitochondrial aldehyde dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300625

Intrathecal mafosfamide: a preclinical pharmacology and phase I trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201300625

Human breast adenocarcinoma MCF-7/0 cells electroporated with cytosolic class 3 aldehyde dehydrogenases obtained from tumor cells and a normal tissue exhibit differential sensitivity to mafosfamide.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4043872

Rate-limiting steps for the esterase and dehydrogenase reaction catalyzed by horse liver aldehyde dehydrogenase

30 October 2018

1 reference

12 December 2020

Cellular levels of class 1 and class 3 aldehyde dehydrogenases and certain other drug-metabolizing enzymes in human breast malignancies

1 reference

12 December 2020

A novel polymorphism (-357 G/A) of the ALDH2 gene: linkage disequilibrium and an association with alcoholism

1 reference

12 December 2020

Mechanisms involved in the protection of UV-induced protein inactivation by the corneal crystallin ALDH3A1

1 reference

12 December 2020

Identifiers

DOI

10.1002/CBIC.201300625

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24677340%20AND%20SRC:MED&resulttype=core&format=json

release_ebjdyuchhfcsrjcsomqjmdt2j4

12 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ebjdyuchhfcsrjcsomqjmdt2j4

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24677340%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PubMed publication ID

24677340

1 reference