Blocking ERK-1/2 reduces tumor necrosis factor alpha-induced interleukin-18 bioactivity in rheumatoid arthritis synovial fibroblasts by induction of interleukin-18 binding protein A (Q33793186)

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English	Blocking ERK-1/2 reduces tumor necrosis factor alpha-induced interleukin-18 bioactivity in rheumatoid arthritis synovial fibroblasts by induction of interleukin-18 binding protein A	scientific article

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17 January 2020

Blocking ERK-1/2 reduces tumor necrosis factor alpha-induced interleukin-18 bioactivity in rheumatoid arthritis synovial fibroblasts by induction of interleukin-18 binding protein A (English)

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17 January 2020

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rheumatoid arthritis

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1

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17 January 2020

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Salahuddin Ahmed

2

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17 January 2020

Jeffrey H Ruth

3

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17 January 2020

Alisa E Koch

4

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publication date

1 March 2010

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17 January 2020

Arthritis and Rheumatism

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17 January 2020

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17 January 2020

3

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17 January 2020

722-731

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17 January 2020

Down-regulation of myeloid cell leukemia 1 by epigallocatechin-3-gallate sensitizes rheumatoid arthritis synovial fibroblasts to tumor necrosis factor alpha-induced apoptosis.

1 reference

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4 July 2018

Expression of interleukin-18, IL-18BP, and IL-18R in serum, synovial fluid, and synovial tissue in patients with rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

Vascular involvement in rheumatic diseases: 'vascular rheumatology'.

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4 July 2018

Epigallocatechin-3-gallate inhibits IL-6 synthesis and suppresses transsignaling by enhancing soluble gp130 production.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

IL-1, IL-18, and IL-33 families of cytokines

1 reference

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4 July 2018

Constitutive expression of IL-18 and IL-18R in differentiated IEC-6 cells: effect of TNF-alpha and IFN-gamma treatment

1 reference

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4 July 2018

Tumor necrosis factor-alpha-induced caspase-1 gene expression. Role of p73.

1 reference

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4 July 2018

Antiviral and immunoregulatory activities of IFN-gamma depend on constitutively expressed IL-1alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

Tumour necrosis factor activates the mitogen-activated protein kinases p38alpha and ERK in the synovial membrane in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

Circulating tumour necrosis factor-alpha bioactivity in rheumatoid arthritis patients treated with infliximab: link to clinical response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

Interleukin-18 promotes joint inflammation and induces interleukin-1-driven cartilage destruction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

Regulation of interleukin-18 binding protein production by blood and synovial cells from patients with rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

TNF-alpha and H2O2 induce IL-18 and IL-18R beta expression in cardiomyocytes via NF-kappa B activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

Lower level of synovial fluid interferon-gamma in HLA-B27-positive than in HLA-B27-negative patients with Chlamydia trachomatis reactive arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

Signal transduction pathways involved in rheumatoid arthritis synovial fibroblast interleukin-18-induced vascular cell adhesion molecule-1 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

Evidence of IL-18 as a novel angiogenic mediator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

Interferon-gamma-inducing activity of interleukin-18 in the joint with rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

Interferon-gamma mediates gene expression of IL-18 binding protein in nonleukocytic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

A proinflammatory role for IL-18 in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

Production of functional IL-18 by different subtypes of murine and human dendritic cells (DC): DC-derived IL-18 enhances IL-12-dependent Th1 development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

A simple and sensitive bioassay for the detection of human interleukin-18/interferon-gamma-inducing factor using human myelomonocytic KG-1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

Production of IL-18 (IFN-gamma-inducing factor) messenger RNA and functional protein by murine keratinocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

4 July 2018

Central role of the MEK/ERK MAP kinase pathway in a mouse model of rheumatoid arthritis: potential proinflammatory mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

30 October 2018

Regulation of JNK by MKK-7 in fibroblast-like synoviocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

30 October 2018

A novel spleen tyrosine kinase inhibitor blocks c-Jun N-terminal kinase-mediated gene expression in synoviocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

30 October 2018

Expression of interleukin-18 and caspase-1 in cutaneous T-cell lymphoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

30 October 2018

Interleukin-18 enhances monocyte tumor necrosis factor alpha and interleukin-1beta production induced by direct contact with T lymphocytes: implications in rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

30 October 2018

Expression of the MAPK kinases MKK-4 and MKK-7 in rheumatoid arthritis and their role as key regulators of JNK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

30 October 2018

Adenoviral delivery of IL-18 binding protein C ameliorates collagen-induced arthritis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

30 October 2018

Interferon-gamma induces expression of interleukin-18 binding protein in fibroblast-like synoviocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

30 October 2018

Blockade of endogenous IL-18 ameliorates TNBS-induced colitis by decreasing local TNF-alpha production in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855552

30 October 2018

Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthr

1 reference

https://pubmed.ncbi.nlm.nih.gov/20131228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the expression of interleukin (IL)-18, IL-18 receptor and IL-18 binding protein in the human endometrium

1 reference

https://pubmed.ncbi.nlm.nih.gov/20131228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fractalkine, a novel chemokine in rheumatoid arthritis and in rat adjuvant-induced arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20131228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12 induces monocyte IL-18 binding protein expression via IFN-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20131228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of inhibition of collagen-induced arthritis by murine IL-18 binding protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/20131228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autopsy study correlating degree of osteoarthritis, synovitis and evidence of articular calcification

1 reference

https://pubmed.ncbi.nlm.nih.gov/20131228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the expression of the TNF alpha receptors (p55 and p75) and their relative contributions to prostanoid production and glycolytic rate by rheumatoid synovial fibroblasts in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20131228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-18 is produced by articular chondrocytes and induces proinflammatory and catabolic responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20131228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/20131228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNF-alpha modulates angiopoietin-1 expression in rheumatoid synovial fibroblasts via the NF-kappa B signalling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/20131228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pro-inflammatory cytokine IL-18 is expressed in human adipose tissue and strongly upregulated by TNFalpha in human adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20131228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-18 induces angiogenic factors in rheumatoid arthritis synovial tissue fibroblasts via distinct signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/20131228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High levels of serum IL-18 promote cartilage loss through suppression of aggrecan synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20131228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between the level of circulating bioactive tumor necrosis factor alpha and the tumor necrosis factor alpha gene polymorphism at -308 in patients with rheumatoid arthritis treated with a tumor necrosis factor alpha inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20131228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A high interleukin 1 receptor antagonist/IL-1beta ratio occurs naturally in knee osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20131228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor alpha-induced interleukin-32 is positively regulated via the Syk/protein kinase Cdelta/JNK pathway in rheumatoid synovial fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20131228

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/ART.27269

1 reference

Europe PubMed Central

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17 January 2020

PMC publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20131228%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20131228%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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