Usefulness of Mendelian randomization in observational epidemiology (Q33858805)

29 July 2017

3 references

19 September 2019

23 July 2020

10 September 2020

Usefulness of Mendelian randomization in observational epidemiology (English)

1 reference

biomedical investigative technique

29 July 2017

main subject

1 reference

19 September 2019

1 reference

genetic predisposition to disease

1 reference

23 July 2020

1 reference

10 September 2020

1

Murielle Bochud

0 references

author name string

Valentin Rousson

series ordinal

2

1 reference

29 July 2017

publication date

26 February 2010

1 reference

International Journal of Environmental Research and Public Health

29 July 2017

1 March 2010

3 references

19 September 2019

23 July 2020

10 September 2020

4 references

29 July 2017

19 September 2019

23 July 2020

10 September 2020

7

1 reference

29 July 2017

issue

3

1 reference

29 July 2017

page(s)

711-728

1 reference

Creative Commons Attribution 3.0 Unported

29 July 2017

copyright license

3 references

19 September 2019

23 July 2020

Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

10 September 2020

0 references

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Unraveling the directional link between adiposity and inflammation: a bidirectional Mendelian randomization approach

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Circulating beta-carotene levels and type 2 diabetes-cause or effect?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Sex hormone-binding globulin and risk of type 2 diabetes in women and men

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

The paraoxonase (PON1) Q192R polymorphism is not associated with poor health status or depression in the ELSA or INCHIANTI studies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Obesity and cancer: Mendelian randomization approach utilizing the FTO genotype

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

RBP4 variants are significantly associated with plasma RBP4 levels and hypertriglyceridemia risk in Chinese Hans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

How does body fat influence bone mass in childhood? A Mendelian randomization approach

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

The association of C-reactive protein and CRP genotype with coronary heart disease: findings from five studies with 4,610 cases amongst 18,637 participants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Does high C-reactive protein concentration increase atherosclerosis? The Whitehall II Study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Inflammation, insulin resistance, and diabetes--Mendelian randomization using CRP haplotypes points upstream

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Lifetime body mass index and later atherosclerosis risk in young adults: examining causal links using Mendelian randomization in the Cardiovascular Risk in Young Finns study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

The CoLaus study: a population-based study to investigate the epidemiology and genetic determinants of cardiovascular risk factors and metabolic syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Mendelian randomization: can genetic epidemiology help redress the failures of observational epidemiology?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Mendelian randomization as an instrumental variable approach to causal inference

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

An interleukin-18 polymorphism is associated with reduced serum concentrations and better physical functioning in older people

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Sequence variations in PCSK9, low LDL, and protection against coronary heart disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Alcohol, ALDH2, and esophageal cancer: a meta-analysis which illustrates the potentials and limitations of a Mendelian randomization approach

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Mendelian randomization: prospects, potentials, and limitations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Evidence for extensive transmission distortion in the human genome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Neonatal and fetal methylenetetrahydrofolate reductase genetic polymorphisms: an examination of C677T and A1298C mutations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

An introduction to instrumental variables for epidemiologists.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Maternal pesticide exposure from multiple sources and selected congenital anomalies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Vitamin E consumption and the risk of coronary heart disease in men.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Apolipoprotein E isoforms, serum cholesterol, and cancer.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Estrogen replacement therapy and coronary heart disease: a quantitative assessment of the epidemiologic evidence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Vitamin C and risk of coronary heart disease in women

5 July 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Aldehyde dehydrogenase 2 and head and neck cancer: a meta-analysis implementing a Mendelian randomization approach

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Commentary: the concept of 'Mendelian Randomization'.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

'Mendelian randomization' equals instrumental variable analysis with genetic instruments

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

A Survey of Weak Instruments and Weak Identification in Generalized Method of Moments

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Insight into the nature of the CRP-coronary event association using Mendelian randomization.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Genetically elevated lipoprotein(a) and increased risk of myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Homocysteine and stroke: evidence on a causal link from mendelian randomisation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Apolipoprotein e genotype, plasma cholesterol, and cancer: a Mendelian randomization study

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Stillbirth and slow metabolizers of caffeine: comparison by genotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Relation of age-related cataract with obesity and obesity genes in an Asian population.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Association between C-reactive protein and adiposity in women

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

C-reactive protein and its role in metabolic syndrome: mendelian randomisation study

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Does greater adiposity increase blood pressure and hypertension risk?: Mendelian randomization using the FTO/MC4R genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Genetic predisposition for adult lactose intolerance and relation to diet, bone density, and bone fractures.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Relationship between leptin and C-reactive protein in young Finnish adults

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Increased frequency of combined methylenetetrahydrofolate reductase C677T and A1298C mutated alleles in spontaneously aborted embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

An integrated approach to the meta-analysis of genetic association studies using Mendelian randomization

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Meta-analysis of genetic studies using Mendelian randomization--a multivariate approach

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Adjusting for bias and unmeasured confounding in Mendelian randomization studies with binary responses

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Polymorphisms of the insulin receptor and the insulin receptor substrates genes in polycystic ovary syndrome: a Mendelian randomization meta-analysis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Associations between lactase persistence and the metabolic syndrome in a cross-sectional study in the Canary Islands

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872313

Challenges and Novel Approaches in the Epidemiological Study of Early Life Influences on Later Disease

29 October 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Effect of macrophage migration inhibitory factor (MIF) gene variants and MIF serum concentrations on the risk of type 2 diabetes: results from the MONICA/KORA Augsburg Case–Cohort Study, 1984–2002

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Association of C-Reactive Protein With Blood Pressure and Hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Mendelian Randomization Suggests No Causal Association Between C-reactive Protein and Carotid Intima-media Thickness in the Young Finns Study

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Systemic inflammation, genetic susceptibility and lung function

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Re: Estimation of Bias in Nongenetic Observational Studies Using “Mendelian Triangulation” by Bautista et al

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

A cautionary note on the use of Mendelian randomization to infer causation in observational epidemiology

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Causal inference with generalized structural mean models

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJERPH7030711

Fibrinogen and coronary heart disease: test of causality by 'Mendelian randomization'

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20616999

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

When are observational studies as credible as randomised trials?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20616999

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Causal diagrams for epidemiologic research

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20616999

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3390/IJERPH7030711

1 reference

29 July 2017

1 reference

29 July 2017

1 reference