The origin of 15R-prostaglandins in the Caribbean coral Plexaura homomalla: molecular cloning and expression of a novel cyclooxygenase (Q33953269)

30 July 2017

title

The origin of 15R-prostaglandins in the Caribbean coral Plexaura homomalla: molecular cloning and expression of a novel cyclooxygenase (English)

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30 July 2017

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Plexaura homomalla

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7

A R Brash

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30 July 2017

K Valmsen

1

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I Järving

2

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W E Boeglin

3

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K Varvas

4

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R Koljak

5

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T Pehk

6

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N Samel

8

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language of work or name

English

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publication date

26 June 2001

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Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

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30 July 2017

volume

98

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30 July 2017

issue

14

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30 July 2017

page(s)

7700-7705

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The basis of prostaglandin synthesis in coral: molecular cloning and expression of a cyclooxygenase from the Arctic soft coral Gersemia fruticosa

30 July 2017

cites work

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Different catalytically competent arrangements of arachidonic acid within the cyclooxygenase active site of prostaglandin endoperoxide H synthase-1 lead to the formation of different oxygenated products

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Spatial requirements for 15-(R)-hydroxy-5Z,8Z,11Z, 13E-eicosatetraenoic acid synthesis within the cyclooxygenase active site of murine COX-2. Why acetylated COX-1 does not synthesize 15-(R)-hete

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Analysis of hydroperoxide-induced tyrosyl radicals and lipoxygenase activity in aspirin-treated human prostaglandin H synthase-2

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Identification and analysis of arachidonic acid in Plexaura homomalla, var. R and var. S.

5 July 2018

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5 July 2018

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On non-cyclooxygenase prostaglandin synthesis in the sea whip coral, Plexaura homomalla: an 8(R)-lipoxygenase pathway leads to formation of an alpha-ketol and a Racemic prostanoid

5 July 2018

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5 July 2018

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The occurrence of 13,14-dihydro and 13,14-cis-unsaturated prostaglandins in the coral, Plexaura homomalla. Synthesis of 13,14-cis-prostaglandin E2, 15-acetate methyl ester, and the 13,14-cis analogues of prostaglandin F2alpha and prostaglandin F2bet

5 July 2018

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5 July 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.131022398

Purification and molecular cloning of an 8R-lipoxygenase from the coral Plexaura homomalla reveal the related primary structures of R- and S-lipoxygenases

21 January 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.131022398

General approach to prostaglandins via methylenecyclopentanones. Total synthesis of (+-)-prostaglandin F2.alpha

21 January 2018

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12 December 2020

Identification of prostaglandins in the gorgonian, Plexaura homomalla

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12 December 2020

Identification of a pharmacologically distinct prostaglandin H synthase in cultured epithelial cells

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12 December 2020

The 3.1 A X-ray crystal structure of the integral membrane enzyme prostaglandin H2 synthase-1

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12 December 2020

Effects of cysteine-to-serine mutations on structural and functional properties of prostaglandin endoperoxide synthase

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12 December 2020

Covalent modification of cyclooxygenase-2 (COX-2) by 2-acetoxyphenyl alkyl sulfides, a new class of selective COX-2 inactivators

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12 December 2020

Evidence of a cyclooxygenase-related prostaglandin synthesis in coral. The allene oxide pathway is not involved in prostaglandin biosynthesis

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12 December 2020

Lipase-catalysed acylation of prostanoids

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12 December 2020

Stereospecificity of hydrogen abstraction in the conversion of arachidonic acid to 15R-HETE by aspirin-treated cyclooxygenase-2. Implications for the alignment of substrate in the active site

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12 December 2020

Oxygenation of Unsaturated Fatty Acids by the Vesicular Gland of Sheep

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12 December 2020

Occurrence of esters of (15S)-prostaglandin A 2 and E 2 in coral

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12 December 2020

Studies on the prostaglandin A 2 synthetase complex from Plexaura homomalla

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12 December 2020

Identifiers

DOI

10.1073/PNAS.131022398

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30 July 2017

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30 July 2017

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