Influence of TCF7L2 gene variants on the therapeutic response to the dipeptidylpeptidase-4 inhibitor linagliptin (Q33990778)

30 July 2017

title

Influence of TCF7L2 gene variants on the therapeutic response to the dipeptidylpeptidase-4 inhibitor linagliptin (English)

1 reference

30 July 2017

Heike Zimdahl

1

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30 July 2017

Carina Ittrich

2

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30 July 2017

Ulrike Graefe-Mody

3

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30 July 2017

Bernhard O Boehm

4

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30 July 2017

Michael Mark

5

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30 July 2017

Hans-Juergen Woerle

6

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30 July 2017

Klaus A Dugi

7

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30 July 2017

publication date

7 June 2014

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30 July 2017

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30 July 2017

volume

57

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30 July 2017

issue

9

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30 July 2017

page(s)

1869-1875

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Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

7 June 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes

5 July 2018

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Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function

5 July 2018

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Association between TCF7L2 gene polymorphisms and susceptibility to type 2 diabetes mellitus: a large Human Genome Epidemiology (HuGE) review and meta-analysis

5 July 2018

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RETRACTED: Transcription factor 7-like 2 regulates beta-cell survival and function in human pancreatic islets

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Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

5 July 2018

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5 July 2018

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TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis

5 July 2018

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The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes

5 July 2018

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Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

5 July 2018

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Variation in TCF7L2 influences therapeutic response to sulfonylureas: a GoDARTs study

5 July 2018

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The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men.

21 January 2018

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Safety and efficacy of linagliptin as add-on therapy to metformin in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled study.

21 January 2018

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Efficacy and safety of linagliptin in persons with type 2 diabetes inadequately controlled by a combination of metformin and sulphonylurea: a 24-week randomized study.

21 January 2018

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Effect of linagliptin monotherapy on glycaemic control and markers of β-cell function in patients with inadequately controlled type 2 diabetes: a randomized controlled trial.

21 January 2018

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Efficacy and safety of initial combination therapy with linagliptin and pioglitazone in patients with inadequately controlled type 2 diabetes: a randomized, double-blind, placebo-controlled study.

21 January 2018

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Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

21 January 2018

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The oral DPP-4 inhibitor linagliptin significantly lowers HbA1c after 4 weeks of treatment in patients with type 2 diabetes mellitus

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24906949

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00125-014-3276-Y

1 reference

Dimensions Publication ID

30 July 2017

0 references

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30 July 2017

1 reference