Mining the ChEMBL database: an efficient chemoinformatics workflow for assembling an ion channel-focused screening library (Q34041986)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21978256%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

title

Mining the ChEMBL database: an efficient chemoinformatics workflow for assembling an ion channel-focused screening library (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21978256%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

0 references

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21978256%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Ruth Brenk

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21978256%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

author name string

N Yi Mok

series ordinal

1

1 reference

PubMed publication ID

21978256

30 July 2017

language of work or name

1 reference

6 October 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21978256%20AND%20SRC:MED&resulttype=core&format=json

Journal of Chemical Information and Modeling

14 February 2020

published in

1 reference

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14 February 2020

volume

51

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21978256%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21978256%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

page(s)

2449-2454

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21978256%20AND%20SRC:MED&resulttype=core&format=json

The design and application of target-focused compound libraries

14 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200031

Screening technologies for ion channel drug discovery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200031

IUPHAR-DB: new receptors and tools for easy searching and visualization of pharmacological data

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200031

Extended-connectivity fingerprints

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200031

Atomic structure and dynamics of pentameric ligand-gated ion channels: new insight from bacterial homologues.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200031

Voltage-gated potassium channels as therapeutic targets

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200031

Novel trends in high-throughput screening

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200031

An ion channel library for drug discovery and safety screening on automated platforms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200031

Drugs and their molecular targets: an updated overview

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200031

Lessons learnt from assembling screening libraries for drug discovery for neglected diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200031

Recent developments in focused library design: targeting gene-families

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200031

High-throughput screening for kinase inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200031

A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200031

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200031

High-throughput screening: update on practices and success

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200031

Prediction of biological targets for compounds using multiple-category Bayesian models trained on chemogenomics databases.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200031

Drug- and lead-likeness, target class, and molecular diversity analysis of 7.9 million commercially available organic compounds provided by 29 suppliers

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21978256

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 reference

21 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/CI200260T

Identifiers

DOI

10.1021/CI200260T

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21978256%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

DBLP publication ID

journals/jcisd/MokB11

1 reference

DBLP Dataset 2021-01-02

release_o53qanedfbgdvpvcwzkfjt3uge

28 January 2021

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/o53qanedfbgdvpvcwzkfjt3uge

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21978256%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

PubMed publication ID

21978256

1 reference