BMP and TGFbeta pathways in human central chondrosarcoma: enhanced endoglin and Smad 1 signaling in high grade tumors (Q34454218)

2 August 2017

title

BMP and TGFbeta pathways in human central chondrosarcoma: enhanced endoglin and Smad 1 signaling in high grade tumors (English)

1 reference

2 August 2017

1 reference

Anne-Marie Cleton-Jansen

6

object named as

Anne-Marie Cleton-Jansen

0 references

Wiltrud Richter

object named as

Wiltrud Richter

7

0 references

Judith Bovée

1 reference

ORCID Public Data File 2021

author name string

Stephane Boeuf

1

1 reference

2 August 2017

Judith V M G Bovée

2

1 reference

2 August 2017

Burkhard Lehner

3

1 reference

2 August 2017

Brendy van den Akker

4

1 reference

2 August 2017

Maayke van Ruler

5

1 reference

2 August 2017

Anne-Marie Cleton-Jansen

6

1 reference

2 August 2017

language of work or name

English

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publication date

22 October 2012

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2 August 2017

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2 August 2017

volume

12

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2 August 2017

page(s)

488

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Interaction of TGFβ and BMP signaling pathways during chondrogenesis

2 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Critical role of endoglin in tumor cell plasticity of Ewing sarcoma and melanoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Signaling by members of the TGF-beta family in vascular morphogenesis and disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Cartilage tumours and bone development: molecular pathology and possible therapeutic targets.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

A role for age-related changes in TGFbeta signaling in aberrant chondrocyte differentiation and osteoarthritis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Autocrine bone morphogenetic protein-9 signals through activin receptor-like kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Bone morphogenetic protein receptors and signal transduction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Aberrant heparan sulfate proteoglycan localization, despite normal exostosin, in central chondrosarcoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Bone morphogenetic protein-2 enhances the motility of chondrosarcoma cells via activation of matrix metalloproteinase-13.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Signaling cross-talk between TGF-beta/BMP and other pathways

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

A chondrogenic gene expression signature in mesenchymal stem cells is a classifier of conventional central chondrosarcoma.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Endoglin (CD105): a marker of tumor vasculature and potential target for therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

L- and S-endoglin differentially modulate TGFbeta1 signaling mediated by ALK1 and ALK5 in L6E9 myoblasts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Endoglin in angiogenesis and vascular diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Coculture with prostate cancer cells alters endoglin expression and attenuates transforming growth factor-beta signaling in reactive bone marrow stromal cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

BMP signaling in the cartilage growth plate.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Bone morphogenetic proteins in bone tumors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Developmental regulation of the growth plate

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Towards a new understanding and classification of chondrogenic neoplasias of the skeleton--biochemistry and cell biology of chondrosarcoma and its variants

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

The clinical significance of tenascin-C splice variant expression in chondrosarcoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

High quality RNA isolation from tumours with low cellularity and high extracellular matrix component for cDNA microarrays: application to chondrosarcoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Expression of bone morphogenetic proteins and receptors in sarcomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3495847

Endoglin differentially regulates TGF-β-induced Smad2/3 and Smad1/5 signalling and its expression correlates with extracellular matrix production and cellular differentiation state in human chondrocytes

6 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-488

Transforming growth factor-beta isoform and receptor expression in chondrosarcoma of bone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-488

cDNA expression profiling of chondrosarcomas: Ollier disease resembles solitary tumours and alteration in genes coding for components of energy metabolism occurs with increasing grade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-488

ALK1 opposes ALK5/Smad3 signaling and expression of extracellular matrix components in human chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-488

Immunophenotypic analysis of human articular chondrocytes: changes in surface markers associated with cell expansion in monolayer culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-488

Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-488

Absence of IHH and retention of PTHrP signalling in enchondromas and central chondrosarcomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-12-488

Changes in surface markers of human mesenchymal stem cells during the chondrogenic differentiation and dedifferentiation processes in vitro

21 January 2018

1 reference

12 December 2020

Correlation of hypoxic signalling to histological grade and outcome in cartilage tumours

1 reference

12 December 2020

Microvasculature and VEGF expression in cartilaginous tumors

1 reference

12 December 2020

Prognostic factors in chondrosarcoma of bone: a clinicopathologic analysis with emphasis on histologic grading

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2407-12-488

1 reference

Dimensions Publication ID

2 August 2017

0 references

1 reference

2 August 2017

1 reference