The P2X(7) loss-of-function Glu496Ala polymorphism affects ex vivo cytokine release and protects against the cytotoxic effects of high ATP-levels (Q34501183)

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English	The P2X(7) loss-of-function Glu496Ala polymorphism affects ex vivo cytokine release and protects against the cytotoxic effects of high ATP-levels	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 August 2017

The P2X(7) loss-of-function Glu496Ala polymorphism affects ex vivo cytokine release and protects against the cytotoxic effects of high ATP-levels (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Ilja C. W. Arts

3

object named as

Ilja C W Arts

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

author name string

Anke Wesselius

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Martijn J L Bours

2

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Europe PubMed Central

PubMed publication ID

2 August 2017

Esther H E Theunisz

4

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Europe PubMed Central

PubMed publication ID

2 August 2017

Piet Geusens

5

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Europe PubMed Central

PubMed publication ID

2 August 2017

Pieter C Dagnelie

6

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Europe PubMed Central

PubMed publication ID

2 August 2017

publication date

4 December 2012

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Europe PubMed Central

PubMed publication ID

2 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

13

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

64

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

copyright license

Creative Commons Attribution 2.0 Generic

1 December 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

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April 2022 Public Data File from Crossref

P2X7 receptors: channels, pores and more

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7 July 2018

Association of P2X7 receptor polymorphisms with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients

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7 July 2018

Regulation of P2X7-dependent inflammatory functions by P2X4 receptor in mouse macrophages

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Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures

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Closing the postfracture care gap using administrative health databases: design and implementation of a randomized controlled trial

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7 July 2018

P2 receptors and extracellular ATP: a novel homeostatic pathway in inflammation

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Role of purinergic receptor polymorphisms in human bone.

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Purinergic mechanism in the immune system: A signal of danger for dendritic cells.

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Liaisons dangereuses: P2X(7) and the inflammasome.

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Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems

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7 July 2018

Osteoimmunology

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7 July 2018

The P2X7 receptor: a key player in IL-1 processing and release

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7 July 2018

Pathophysiology and therapeutic potential of purinergic signaling

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7 July 2018

Interleukin-1 and neuronal injury

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7 July 2018

Pseudoapoptosis induced by brief activation of ATP-gated P2X7 receptors.

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7 July 2018

Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain

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7 July 2018

The cytokine IL-1beta transiently enhances P2X7 receptor expression and function in human astrocytes.

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7 July 2018

Osteoclast differentiation and activation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526505

7 July 2018

Measurement of adenine nucleotides in plasma

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7 July 2018

Absence of the P2X7 receptor alters leukocyte function and attenuates an inflammatory response

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526505

7 July 2018

A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526505

7 July 2018

Extracellular ATP triggers tumor necrosis factor-alpha release from rat microglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526505

7 July 2018

P2Z purinoreceptor ligation induces activation of caspases with distinct roles in apoptotic and necrotic alterations of cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526505

7 July 2018

The permeabilizing ATP receptor, P2X7. Cloning and expression of a human cDNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526505

7 July 2018

Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526505

7 July 2018

The purinergic P2Z receptor of human macrophage cells. Characterization and possible physiological role

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7 July 2018

The P2Z purinoceptor: an intriguing role in immunity, inflammation and cell death

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526505

7 July 2018

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

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7 July 2018

ATP inhibits hydroxyl radical formation and the inflammatory response of stimulated whole blood even under circumstances of severe oxidative stress

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https://api.crossref.org/works/10.1186%2F1471-2172-13-64

21 January 2018

Immunoregulatory effects of adenosine 5'-triphosphate on cytokine release from stimulated whole blood

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21 January 2018

P2X7 receptor polymorphism impairs extracellular adenosine 5'-triphosphate-induced interleukin-18 release from human monocytes

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21 January 2018

Radioprotective effects of ATP in human blood ex vivo

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21 January 2018

The role of the purinergic P2X7 receptor in inflammation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526505

27 October 2018

Detection of human P2X7 nucleotide receptor polymorphisms by a novel monocyte pore assay predictive of alterations in lipopolysaccharide-induced cytokine production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526505

27 October 2018

Glu496 to Ala polymorphism in the P2X7 receptor impairs ATP-induced IL-1 beta release from human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526505

27 October 2018

Single nucleotide polymorphisms in the P2X7 gene are associated to fracture risk and to effect of estrogen treatment

1 reference

https://api.crossref.org/works/10.1186%2F1471-2172-13-64

21 January 2018

Human primary fibroblasts in vitro express a purinergic P2X7 receptor coupled to ion fluxes, microvesicle formation and IL-6 release

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https://pubmed.ncbi.nlm.nih.gov/23210974

12 December 2020

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Partial agonists and antagonists reveal a second permeability state of human lymphocyte P2Z/P2X7 channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/23210974

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Purinergic receptors involved in the immunomodulatory effects of ATP in human blood

1 reference

https://pubmed.ncbi.nlm.nih.gov/23210974

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Mechanisms of death induced by cisplatin in proximal tubular epithelial cells: apoptosis vs. necrosis

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10.1186/1471-2172-13-64

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Europe PubMed Central

PubMed publication ID

2 August 2017

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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