The biology of CD45 and its use as a therapeutic target (Q34547284)

2 August 2017

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title

The biology of CD45 and its use as a therapeutic target (English)

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2 August 2017

Marc H Dahlke

1

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2 August 2017

Stephen R Larsen

series ordinal

2

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2 August 2017

John E J Rasko

series ordinal

3

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2 August 2017

Hans J Schlitt

series ordinal

4

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2 August 2017

publication date

1 February 2004

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2 August 2017

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2 August 2017

volume

45

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2 August 2017

issue

2

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2 August 2017

page(s)

229-236

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The regulation of B- and T-lymphocyte activation by the transmembrane protein tyrosine phosphatase CD45.

2 August 2017

cites work

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The leukocyte common antigen, CD45 and other protein tyrosine phosphatases in hematopoietic cells

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Leukocyte cell surface enzymology: CD45 (LCA, T200) is a protein tyrosine phosphatase

21 January 2018

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CD45: a critical regulator of signaling thresholds in immune cells

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Positive and negative regulation of Src-family membrane kinases by CD45.

21 January 2018

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Human B cells express a CD45 isoform that is similar to murine B220 and is downregulated with acquisition of the memory B-cell marker CD27.

21 January 2018

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Prognostic impact of CD45 antigen expression in high-risk, childhood B-cell precursor acute lymphoblastic leukemia

21 January 2018

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The leukocyte common antigen (CD45) of the Pacific hagfish, Eptatretus stoutii: implications for the primordial function of CD45.

21 January 2018

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Manipulation of CD45 antigen in transplantation tolerance

21 January 2018

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In vivo depletion of hematopoietic stem cells in the rat by an anti-CD45 (RT7) antibody

21 January 2018

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Expression of CD45 isoforms lacking exons 7, 8 and 10.

21 January 2018

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Functional subsets of T cells defined by isoforms of CD45.

21 January 2018

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Isoforms of the CD45 common leukocyte antigen family: markers for human T-cell differentiation

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Generation of CD4(+)CD45RA(+) effector T cells by stimulation in the presence of cyclic adenosine 5'-monophosphate-elevating agents

21 January 2018

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PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients

21 January 2018

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CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signaling

21 January 2018

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CD45 controls interleukin-4-mediated IgE class switch recombination in human B cells through its function as a Janus kinase phosphatase

21 January 2018

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The role of CD45 and CD45-associated molecules in T cell activation

21 January 2018

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The CD45 tyrosine phosphatase: a positive and negative regulator of immune cell function

21 January 2018

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CD45 and Src-family kinases: and now for something completely different

21 January 2018

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The role of p56lck and p59fyn tyrosine kinases and CD45 protein tyrosine phosphatase in T-cell development and clonal selection

21 January 2018

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Human activation-induced cytidine deaminase is induced by IL-4 and negatively regulated by CD45: implication of CD45 as a Janus kinase phosphatase in antibody diversification

21 January 2018

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Differential regulation of CXCR4-mediated T-cell chemotaxis and mitogen-activated protein kinase activation by the membrane tyrosine phosphatase, CD45.

21 January 2018

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New insights into the transmembrane protein tyrosine phosphatase CD45.

21 January 2018

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Effects of the protein tyrosine phosphatase CD45 on FcgammaRIIa signaling and neutrophil function

21 January 2018

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Anti-CD45 isoform antibodies enhance phagocytosis and gene expression of IL-8 and TNF-alpha in human neutrophils by differential suppression on protein tyrosine phosphorylation and p56lck tyrosine kinase

21 January 2018

1 reference

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Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms

21 January 2018

1 reference

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An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity

21 January 2018

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Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge

21 January 2018

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A CD45 minigene restores regulated isoform expression and immune function in CD45-deficient mice: therapeutic implications for human CD45-null severe combined immunodeficiency

21 January 2018

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Autoantibodies to CD45 in systemic lupus erythematosus

21 January 2018

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Anti-CD45-mediated cytoreduction to facilitate allogeneic stem cell transplantation

21 January 2018

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Bismuth 213-labeled anti-CD45 radioimmunoconjugate to condition dogs for nonmyeloablative allogeneic marrow grafts

21 January 2018

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Antibody-mediated targeting of CD45 isoforms: a novel immunotherapeutic strategy

21 January 2018

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Comparison of anti-CD20 and anti-CD45 antibodies for conventional and pretargeted radioimmunotherapy of B-cell lymphomas.

21 January 2018

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A point mutation in PTPRC is associated with the development of multiple sclerosis

21 January 2018

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https://api.crossref.org/works/10.1080%2F1042819031000151932

Quantification of the leukocyte common antigen (CD45) in mature B-cell malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819031000151932

Requirements of src family kinase activity associated with CD45 for myeloma cell proliferation by interleukin-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819031000151932

Mutations in the tyrosine phosphatase CD45 gene in a child with severe combined immunodeficiency disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819031000151932

Differential effects of anti-CD45 monoclonal antibody on human B cell proliferation: a monoclonal antibody recognizing a neuraminidase-sensitive epitope of the T200 molecule enhances anti-immunoglobulin-induced proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819031000151932

In vitro and in vivo effects of an anti-CD45 monoclonal antibody in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819031000151932

The functional relevance of passenger leukocytes and microchimerism for heart allograft acceptance in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819031000151932

Bone marrow aplasia induced by passenger leukocytes from heart allografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1042819031000151932

10.1080/1042819031000151932

21 January 2018

Identifiers

DOI

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2 August 2017

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