Interrogating a hexokinase-selected small-molecule library for inhibitors of Plasmodium falciparum hexokinase (Q34743561)

4 August 2017

title

Interrogating a hexokinase-selected small-molecule library for inhibitors of Plasmodium falciparum hexokinase (English)

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4 August 2017

main subject

Plasmodium falciparum

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10 September 2018

William G Mitchell

4

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Jennifer E. Golden

object named as

Jennifer E Golden

9

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author name string

Michael T Harris

1

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4 August 2017

Dawn M Walker

2

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4 August 2017

Mark E Drew

3

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4 August 2017

Kevin Dao

5

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4 August 2017

Chad E Schroeder

6

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4 August 2017

Daniel P Flaherty

7

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4 August 2017

Warren S Weiner

8

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4 August 2017

James C Morris

10

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4 August 2017

language of work or name

English

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publication date

28 May 2013

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Antimicrobial Agents and Chemotherapy

4 August 2017

published in

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4 August 2017

volume

57

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4 August 2017

issue

8

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4 August 2017

page(s)

3731-3737

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Identification of Inhibitors of Trypanosoma brucei Hexokinases

4 August 2017

cites work

1 reference

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Glycerol 3-phosphate alters Trypanosoma brucei hexokinase activity in response to environmental change

7 July 2018

1 reference

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Branched tricarboxylic acid metabolism in Plasmodium falciparum

7 July 2018

1 reference

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Thousands of chemical starting points for antimalarial lead identification

7 July 2018

1 reference

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A target-based high throughput screen yields Trypanosoma brucei hexokinase small molecule inhibitors with antiparasitic activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719756

Life cycle studies of the hexose transporter of Plasmodium species and genetic validation of their essentiality

7 July 2018

1 reference

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The selenazal drug ebselen potently inhibits indoleamine 2,3-dioxygenase by targeting enzyme cysteine residues

7 July 2018

1 reference

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Mitochondrial evolution and functions in malaria parasites.

7 July 2018

1 reference

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The inhibitory effect of 2-halo derivatives of D-glucose on glycolysis and on the proliferation of the human malaria parasite Plasmodium falciparum

7 July 2018

1 reference

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Activity of a second Trypanosoma brucei hexokinase is controlled by an 18-amino-acid C-terminal tail.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719756

Redox and antioxidant systems of the malaria parasite Plasmodium falciparum

7 July 2018

1 reference

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Characterisation of hexokinase in Toxoplasma gondii tachyzoites

7 July 2018

1 reference

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Antimalarial properties of ebselen

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719756

Molecular analysis of Plasmodium falciparum hexokinase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719756

Effect of diphenyl diselenide, diphenyl ditelluride and ebselen on cerebral Na(+), K(+)-ATPase activity in rats.

7 July 2018

1 reference

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Inhibition of hexose transport and abrogation of pH homeostasis in the intraerythrocytic malaria parasite by an O-3-hexose derivative

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719756

Glutathione stability and oxidative stress in P. falciparum infection in vitro: responses of normal and G6PD deficient cells

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719756

Malarial parasite hexokinase and hexokinase-dependent glutathione reduction in the Plasmodium falciparum-infected human erythrocyte.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3719756

2-Deoxyglucose: inhibition of parasitemia and of glucosamine incorporation into glycosylated macromolecules, in malarial parasites (Plasmodium falciparum)

26 October 2018

1 reference

12 December 2020

Plasmodium falciparum: stage-specific lactate production in synchronized cultures

1 reference

12 December 2020

Hexokinase type II from rat skeletal muscle

1 reference

12 December 2020

Simultaneous purification of hexokinase, class-I fructose-bisphosphate aldolase, triosephosphate isomerase and phosphoglycerate kinase from Trypanosoma brucei

1 reference

12 December 2020

D-lactate production in erythrocytes infected with Plasmodium falciparum

1 reference

12 December 2020

Identifiers

DOI

10.1128/AAC.00662-13

1 reference

4 August 2017

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4 August 2017

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