Driving p53 response to Bax activation greatly enhances sensitivity to taxol by inducing massive apoptosis. (Q34785151)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10935506%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Driving p53 response to Bax activation greatly enhances sensitivity to taxol by inducing massive apoptosis (English)

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9 November 2019

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5

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9 November 2019

Maurizio D'Incalci

6

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9 November 2019

Massimo Broggini

7

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9 November 2019

author name string

P De Feudis

1

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9 November 2019

S Vignati

2

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9 November 2019

C Rossi

3

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9 November 2019

T Mincioni

4

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9 November 2019

publication date

1 May 2000

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9 November 2019

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9 November 2019

volume

2

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9 November 2019

issue

3

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9 November 2019

page(s)

202-207

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Inactivation of p53 in a human ovarian cancer cell line increases the sensitivity to paclitaxel by inducing G2/M arrest and apoptosis

9 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

DNA damage induces phosphorylation of the amino terminus of p53

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

DDP-induced cytotoxicity is not influenced by p53 in nine human ovarian cancer cell lines with different p53 status.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

Binding and modulation of p53 by p300/CBP coactivators

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

Conformation-dependent phosphorylation of p53.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

p53 status does not affect sensitivity of human ovarian cancer cell lines to paclitaxel

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

p53, the cellular gatekeeper for growth and division

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

Differential effects of phosphorylation of rat p53 on transactivation of promoters derived from different p53 responsive genes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

Bax homodimerization is not required for Bax to accelerate chemotherapy-induced cell death

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

BAX enhances paclitaxel-induced apoptosis through a p53-independent pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

p53 in signaling checkpoint arrest or apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

WAF1, a potential mediator of p53 tumor suppression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

Antitumor activity of taxol (NSC-125973) in human ovarian carcinomas growing in the peritoneal cavity of nude mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

Reduced expression of proapoptotic gene BAX is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

p21 is necessary for the p53-mediated G1 arrest in human cancer cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1507571

Overexpression of Bax gene sensitizes K562 erythroleukemia cells to apoptosis induced by selective chemotherapeutic agents

7 July 2018

1 reference

12 December 2020

Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

1 reference

12 December 2020

Phase II preclinical drug screening in human tumor xenografts: a first European multicenter collaborative study

1 reference

12 December 2020

Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis

1 reference

12 December 2020

Overexpression of bax sensitizes human breast cancer MCF-7 cells to radiation-induced apoptosis

1 reference

12 December 2020

p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

1 reference

12 December 2020

p53: upstream, downstream and off stream. Review of the 8th p53 workshop (Dundee, July 5-9, 1996)

1 reference

12 December 2020

Differential activation of p53 targets in cells treated with ultraviolet radiation that undergo both apoptosis and growth arrest

1 reference

12 December 2020

Cell-cycle arrest versus cell death in cancer therapy

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.NEO.7900086

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10935506%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

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9 November 2019

PubMed publication ID

10935506

1 reference