Genetic variations in the α(2A)-adrenoreceptor are associated with blood pressure response to the agonist dexmedetomidine (Q34827577)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21325151%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Genetic variations in the α(2A)-adrenoreceptor are associated with blood pressure response to the agonist dexmedetomidine (English)

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22 January 2020

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2

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22 January 2020

Chun Li

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22 January 2020

Mika Scheinin

6

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22 January 2020

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Gbenga G Sofowora

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22 January 2020

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Alastair J J Wood

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22 January 2020

1

Daniel Kurnik

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22 January 2020

author name string

Eitan A Friedman

5

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22 January 2020

C Michael Stein

8

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22 January 2020

language of work or name

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15 February 2011

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Circulation: Cardiovascular Genetics

22 January 2020

published in

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22 January 2020

volume

4

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22 January 2020

issue

2

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22 January 2020

page(s)

179-187

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Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists

22 January 2020

cites work

1 reference

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Leveraging genetic variability across populations for the identification of causal variants.

8 July 2018

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New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

8 July 2018

1 reference

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Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes

8 July 2018

1 reference

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Targeting 160 candidate genes for blood pressure regulation with a genome-wide genotyping array

8 July 2018

1 reference

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Genome-wide association study identifies eight loci associated with blood pressure

8 July 2018

1 reference

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Effects of variation in the human alpha2A- and alpha2C-adrenoceptor genes on cognitive tasks and pain perception.

8 July 2018

1 reference

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Beta-1-adrenoceptor genetic variants and ethnicity independently affect response to beta-blockade.

8 July 2018

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Alpha2-adrenoceptor subtypes--unexpected functions for receptors and ligands derived from gene-targeted mouse models.

8 July 2018

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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

8 July 2018

1 reference

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Complex haplotypes derived from noncoding polymorphisms of the intronless alpha2A-adrenergic gene diversify receptor expression

8 July 2018

1 reference

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Haplotype-based analysis of alpha 2A, 2B, and 2C adrenergic receptor genes captures information on common functional loci at each gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080459

An asn to lys polymorphism in the third intracellular loop of the human alpha 2A-adrenergic receptor imparts enhanced agonist-promoted Gi coupling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080459

The effects of increasing plasma concentrations of dexmedetomidine in humans

8 July 2018

1 reference

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Two functionally distinct alpha2-adrenergic receptors regulate sympathetic neurotransmission

8 July 2018

1 reference

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Abnormal regulation of the sympathetic nervous system in alpha2A-adrenergic receptor knockout mice.

8 July 2018

1 reference

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Alpha 2-adrenergic receptor gene polymorphism and hypertension in blacks

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080459

Ethnic and genetic determinants of cardiovascular response to the selective alpha 2-adrenoceptor agonist dexmedetomidine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080459

Effects of low and high plasma concentrations of dexmedetomidine on myocardial perfusion and cardiac function in healthy male subjects.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080459

Variations in the alpha2A-adrenergic receptor gene and their functional effects.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080459

Comparative analgesic and mental effects of increasing plasma concentrations of dexmedetomidine and alfentanil in humans

26 October 2018

1 reference

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Simultaneous quantitation of dexmedetomidine and glucuronide metabolites (G-Dex-1 and G-Dex-2) in human plasma utilizing liquid chromatography with tandem mass spectrometric detection

26 October 2018

1 reference

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The effect of common polymorphisms of the beta2-adrenergic receptor on agonist-mediated vascular desensitization

26 October 2018

1 reference

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Sympathoinhibitory function of the alpha(2A)-adrenergic receptor subtype

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080459

Do allelic variants in alpha2A and alpha2C adrenergic receptors predispose to hypertension in blacks?

26 October 2018

1 reference

12 December 2020

Functional correlates of alpha(2A)-adrenoceptor gene polymorphism in the HANE study

1 reference

12 December 2020

SNP genotyping by the 5'-nuclease reaction

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12 December 2020

Optimization of high-performance liquid chromatographic assay for catecholamines. Determination of optimal mobile phase composition and elimination of species-dependent differences in extraction recovery of 3,4-dihydroxybenzylamine

1 reference

12 December 2020

Association of hypertension with beta2- and alpha2c10-adrenergic receptor genotype

1 reference

12 December 2020

10.1161/CIRCGENETICS.110.957662

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21325151%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21325151%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

21325151

1 reference