Prostanoid signaling: dual role for prostaglandin E2 in neurotoxicity (Q34954633)

5 August 2017

1 reference

title

Prostanoid signaling: dual role for prostaglandin E2 in neurotoxicity (English)

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5 August 2017

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3

Michael Aschner

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5 August 2017

1

Dejan Milatovic

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5 August 2017

2

Thomas J Montine

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5 August 2017

publication date

3 March 2011

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5 August 2017

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5 August 2017

volume

32

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5 August 2017

issue

3

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5 August 2017

page(s)

312-319

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Activation of NAD(P)H oxidases by thromboxane A2 receptor uncouples endothelial nitric oxide synthase.

5 August 2017

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Contrary prostaglandins: the opposing roles of PGD2 and its metabolites in leukocyte function.

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Human prostaglandin EP3 receptor isoforms show different agonist-induced internalization patterns

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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G protein-coupled prostanoid receptors and the kidney

8 July 2018

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Anti-inflammatory effects of prostaglandin E2 in the central nervous system in response to brain injury and circulating lipopolysaccharide

8 July 2018

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The human prostanoid DP receptor stimulates mucin secretion in LS174T cells

8 July 2018

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Specific physiological roles of cytosolic phospholipase A(2) as defined by gene knockouts

8 July 2018

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Relationship of EP(1-4) prostaglandin receptors with rat hypothalamic cell groups involved in lipopolysaccharide fever responses

8 July 2018

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Cyclooxygenases: structural, cellular, and molecular biology

8 July 2018

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15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway.

8 July 2018

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Prostaglandin receptors: their role in regulating renal function

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Distribution, regulation and colocalization of the genes encoding the EP2- and EP4-PGE2 receptors in the rat brain and neuronal responses to systemic inflammation

26 October 2018

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The 85-kD cytosolic phospholipase A2 knockout mouse: a new tool for physiology and cell biology

8 July 2018

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Nuclear localization of prostaglandin E2 receptors

8 July 2018

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Expression and tissue distribution of the mRNAs encoding the human thromboxane A2 receptor (TP) alpha and beta isoforms

8 July 2018

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Prostaglandin E2 and 4-aminopyridine prevent the lipopolysaccharide-induced outwardly rectifying potassium current and interleukin-1beta production in cultured rat microglia

8 July 2018

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The isoprostanes: unique bioactive products of lipid peroxidation

8 July 2018

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Characterization of the prostanoid receptor(s) on human blood monocytes at which prostaglandin E2 inhibits lipopolysaccharide-induced tumour necrosis factor-alpha generation

8 July 2018

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Altered pain perception and inflammatory response in mice lacking prostacyclin receptor

8 July 2018

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Failure of parturition in mice lacking the prostaglandin F receptor

8 July 2018

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Phospholipases: structural and functional motifs for working at an interface

8 July 2018

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Prostaglandin synthase 2.

8 July 2018

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Cloning and expression of a cDNA for mouse prostaglandin E receptor EP2 subtype.

8 July 2018

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Cloning and expression of a cDNA for the human prostanoid FP receptor

8 July 2018

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Prostaglandin F2 alpha enhances tyrosine phosphorylation and DNA synthesis through phospholipase C-coupled receptor via Ca(2+)-dependent intracellular pathway in NIH-3T3 cells.

8 July 2018

1 reference

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Molecular characterization of a mouse prostaglandin D receptor and functional expression of the cloned gene

8 July 2018

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Pharmacodynamic profile of prostacyclin

8 July 2018

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Molecular Cloning and Characterization of the Human Prostanoid DP Receptor

8 July 2018

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Induction of Prostanoid Biosynthesis by Bacterial Lipopolysaccharide and Isoproterenol in Rat Microglial Cultures

8 July 2018

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Prostaglandin D2 in rat brain, spinal cord and pituitary: basal level and regional distribution

8 July 2018

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Inositol trisphosphate, a novel second messenger in cellular signal transduction

8 July 2018

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The biology and pharmacology of PGD2.

8 July 2018

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Prostaglandin D2, a cerebral sleep-inducing substance in monkeys

8 July 2018

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Different responsiveness of prostaglandin D2-sensitive systems to prostaglandin D2 and its analogues

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Prostaglandin D2 causes accumulation of eosinophils in the lumen of the dog trachea

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Prostanoid-induced contraction of human bronchial smooth muscle is mediated by TP-receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Hemorrhage and intracranial hypertension in combination increase cerebral production of thromboxane A2.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Leukotriene C4 and prostaglandin E2 activities in the serum and cerebrospinal fluid during acute cerebral ischemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Prostanoid biosynthesis and mechanisms of action

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

The localization of PGE2 receptor subtypes in rat retinal cultures and the neuroprotective effect of the EP2 agonist butaprost.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

An improved LC-MS/MS procedure for brain prostanoid analysis using brain fixation with head-focused microwave irradiation and liquid-liquid extraction

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Increased cortical cell loss and prolonged hemodynamic depression after traumatic brain injury in mice lacking the IP receptor for prostacyclin.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Stimulation of prostaglandin EP2 receptors prevents NMDA-induced excitotoxicity

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Inhibition of prostaglandin F(2alpha) by selective cyclooxygenase 2 inhibitors accounts for reduced rat leukocyte migration.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Prostaglandin D2-mediated microglia/astrocyte interaction enhances astrogliosis and demyelination in twitcher.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Profiling of eicosanoid production in the rat hippocampus during kainic acid-induced seizure: dual phase regulation and differential involvement of COX-1 and COX-2.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Prostaglandin E2 EP1 receptors: downstream effectors of COX-2 neurotoxicity

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Involvement of brain thromboxane A in hypotension induced by haemorrhage in rats

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Deletion of the prostaglandin E2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

The involvement of central cholinergic system in the pressor effect of intracerebroventricularly injected U-46619, a thromboxane A2 analog, in conscious normotensive rats.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Microglial EP2 is critical to neurotoxicity from activated cerebral innate immunity

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Neuroprotection by the PGE2 EP2 receptor in permanent focal cerebral ischemia

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Drug safety. FDA panel urges caution on many anti-inflammatory drugs

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Prostaglandin D2 mediates neuronal protection via the DP1 receptor

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

PGE2 receptors rescue motor neurons in a model of amyotrophic lateral sclerosis

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Prostaglandin E2 induced caspase-dependent apoptosis possibly through activation of EP2 receptors in cultured hippocampal neurons

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Pharmacologic suppression of neuronal oxidative damage and dendritic degeneration following direct activation of glial innate immunity in mouse cerebrum

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Prostaglandin E2 is increased in amyotrophic lateral sclerosis patients.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Evidence for time-dependent maximum increase of free radical damage and eicosanoid formation in the brain as related to duration of cardiac arrest and cardio-pulmonary resuscitation

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Neuronal oxidative damage from activated innate immunity is EP2 receptor-dependent

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Peroxynitrite mediates neurotoxicity of amyloid beta-peptide1-42- and lipopolysaccharide-activated microglia.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Increased levels of the pro-inflammatory prostaglandin PGE2 in CSF from ALS patients

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Mechanisms of prostaglandin E2-induced interleukin-6 release in astrocytes: possible involvement of EP4-like receptors, p38 mitogen-activated protein kinase and protein kinase C.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Propofol (Diprivan-EDTA) counteracts oxidative injury and deterioration of the arterial oxygen tension during experimental septic shock

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Infusion of prostacyclin following experimental brain injury in the rat reduces cortical lesion volume.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Low-dose prostacyclin in treatment of severe brain trauma evaluated with microdialysis and jugular bulb oxygen measurements.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Thromboxane A2 is involved in the nitric oxide-induced central activation of adrenomedullary outflow in rats

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Central thromboxane receptors: mRNA expression and mediation of pressor responses

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Prostaglandin F2 alpha induces cardiac myocyte hypertrophy in vitro and cardiac growth in vivo

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Elevated central nervous system prostaglandins in human immunodeficiency virus-associated dementia

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Prostaglandin D2 generation after activation of rat and human mast cells with anti-IgE.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090136

Prostanoid and TP-receptors in atherothrombosis: Is there a role for their antagonism?

26 October 2018

1 reference

12 December 2020

Two isoforms of the prostaglandin E receptor EP3 subtype different in agonist-independent constitutive activity

1 reference

12 December 2020

Increased prostaglandin formation in rat brain following systemic application of kainic acid

1 reference

12 December 2020

Elevated CSF prostaglandin E2 levels in patients with probable AD

1 reference

12 December 2020

Inducible nitric oxide synthase expression in activated rat microglial cultures is downregulated by exogenous prostaglandin E2 and by cyclooxygenase inhibitors

1 reference

12 December 2020

Prostaglandin E2 protects cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity

1 reference

12 December 2020

Distribution of the messenger RNA for the prostaglandin E receptor subtype EP3 in the mouse nervous system

1 reference

12 December 2020

PGE(2) receptor EP1 renders dopaminergic neurons selectively vulnerable to low-level oxidative stress and direct PGE(2) neurotoxicity

1 reference

12 December 2020

Modulation of the bronchomotor effects of chemical mediators by prostaglandin F2 alpha in asthmatic subjects

1 reference

12 December 2020

Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice

1 reference

12 December 2020

Trial of celecoxib in amyotrophic lateral sclerosis

1 reference

12 December 2020

Immunohistochemical localization of prostaglandin EP3 receptor in the rat nervous system

1 reference

12 December 2020

Inducible cyclooxygenase may have anti-inflammatory properties

1 reference

12 December 2020

10.1016/J.NEURO.2011.02.004

Identifiers

DOI

1 reference

release_h332nyzonncjtb26xxj34u4uea

5 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/h332nyzonncjtb26xxj34u4uea

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3090136

1 reference

5 August 2017

1 reference