Two phases of mitogenic signaling unveil roles for p53 and EGR1 in elimination of inconsistent growth signals (Q35000817)

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1 February 2020

title

Two phases of mitogenic signaling unveil roles for p53 and EGR1 in elimination of inconsistent growth signals (English)

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1 February 2020

3

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1 February 2020

Tal Shay

4

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1 February 2020

Roi Avraham

5

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1 February 2020

Mattia Lauriola

6

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1 February 2020

Efrat Shema

7

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1 February 2020

Moshe Oren

14

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13

Gideon Rechavi

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1 February 2020

10

Ninette Amariglio

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1 February 2020

15

Eytan Domany

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1 February 2020

12

Gordon B Mills

1 reference

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1 February 2020

author name string

Yaara Zwang

1

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1 February 2020

Aldema Sas-Chen

2

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1 February 2020

Efrat Lidor-Nili

8

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Jasmine Jacob-Hirsch

9

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1 February 2020

Yiling Lu

11

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1 February 2020

Yosef Yarden

16

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1 February 2020

publication date

1 May 2011

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1 February 2020

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1 February 2020

volume

42

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issue

4

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1 February 2020

page(s)

524-535

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Intensity dependent estimation of noise in microarrays improves detection of differentially expressed genes

1 February 2020

cites work

1 reference

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Basal dynamics of p53 reveal transcriptionally attenuated pulses in cycling cells.

8 July 2018

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A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases

8 July 2018

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Emerging roles of E2Fs in cancer: an exit from cell cycle control

8 July 2018

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The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis

8 July 2018

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Cell growth and size homeostasis in proliferating animal cells

8 July 2018

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Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

8 July 2018

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Reflecting on 25 years with MYC.

8 July 2018

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A bistable Rb-E2F switch underlies the restriction point

8 July 2018

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An E2F1-dependent gene expression program that determines the balance between proliferation and cell death

8 July 2018

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CellProfiler: image analysis software for identifying and quantifying cell phenotypes

8 July 2018

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Phosphoinositide 3-kinase activation in late G1 is required for c-Myc stabilization and S phase entry

8 July 2018

1 reference

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Continuous ERK activation downregulates antiproliferative genes throughout G1 phase to allow cell-cycle progression.

8 July 2018

1 reference

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The priming/completion paradigm to explain growth factor-dependent cell cycle progression

8 July 2018

1 reference

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EGFR blockade by cetuximab alone or as combination therapy for growth control of hepatocellular cancer

8 July 2018

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Growth factor regulation of cell cycle progression in mammary epithelial cells.

8 July 2018

1 reference

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DAVID: Database for Annotation, Visualization, and Integrated Discovery

8 July 2018

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Retinoids suppress epidermal growth factor-associated cell proliferation by inhibiting epidermal growth factor receptor-dependent ERK1/2 activation.

8 July 2018

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Growth-factor-dependent mitogenesis requires two distinct phases of signalling

8 July 2018

1 reference

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Phosphoinositide 3-OH kinase (PI3K) and PKB/Akt delay the onset of p53-mediated, transcriptionally dependent apoptosis

8 July 2018

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PDGF induces an early and a late wave of PI 3-kinase activity, and only the late wave is required for progression through G1.

8 July 2018

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The transcriptional program in the response of human fibroblasts to serum

8 July 2018

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Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

8 July 2018

1 reference

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Distinct p53-mediated G1/S checkpoint responses in two NIH3T3 subclone cells following treatment with DNA-damaging agents.

8 July 2018

1 reference

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Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended serial passage with pituitary extract

8 July 2018

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A Restriction Point for Control of Normal Animal Cell Proliferation

8 July 2018

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Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types

8 July 2018

1 reference

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G1 events and regulation of cell proliferation

8 July 2018

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Induction of DNA synthesis in BALB/c 3T3 cells by serum components: Reevaluation of the commitment process

8 July 2018

1 reference

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Control of the Balb/c-3T3 cell cycle by nutrients and serum factors: Analysis using platelet-derived growth factor and platelet-poor plasma

8 July 2018

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A role for Myc in facilitating transcription activation by E2F1.

8 July 2018

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A module of negative feedback regulators defines growth factor signaling

26 October 2018

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P27 expression is regulated by separate signaling pathways, downstream of Ras, in each cell cycle phase

26 October 2018

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Evidence for a size-sensing mechanism in animal cells

26 October 2018

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Faster cyclic loess: normalizing RNA arrays via linear models.

26 October 2018

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Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53.

26 October 2018

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The restriction point and control of cell proliferation

26 October 2018

1 reference

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Blockage of EGF receptor signal transduction causes reversible arrest of normal and immortal human mammary epithelial cells with synchronous reentry into the cell cycle

26 October 2018

1 reference

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Biphasic and synergistic activation of p44mapk (ERK1) by growth factors: correlation between late phase activation and mitogenicity

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21596316

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Patterns of EGFR, HER2, TP53, and KRAS mutations of p14arf expression in non-small cell lung cancers in relation to smoking history

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21596316

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLCEL.2011.04.017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21596316%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

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1 February 2020

PubMed publication ID

21596316

1 reference