Therapeutic potential of antisense oligonucleotides as modulators of alternative splicing (Q35202466)

7 August 2017

1 reference

title

Therapeutic potential of antisense oligonucleotides as modulators of alternative splicing (English)

1 reference

alternative mRNA splicing, via spliceosome

7 August 2017

main subject

1 reference

2

Ryszard Kole

1 reference

7 August 2017

Peter Sazani

1

1 reference

7 August 2017

language of work or name

English

0 references

publication date

1 August 2003

1 reference

Journal of Clinical Investigation

7 August 2017

published in

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7 August 2017

volume

112

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7 August 2017

issue

4

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7 August 2017

page(s)

481-486

1 reference

Repair of a splicing defect in erythroid cells from patients with beta-thalassemia/HbE disorder

7 August 2017

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13 July 2018

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13 July 2018

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13 July 2018

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Modification of alternative splicing by antisense oligonucleotides as a potential chemotherapy for cancer and other diseases

13 July 2018

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Restoration of human beta-globin gene expression in murine and human IVS2-654 thalassemic erythroid cells by free uptake of antisense oligonucleotides.

13 July 2018

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13 July 2018

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Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs

13 July 2018

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Correction of alternative splicing of tau in frontotemporal dementia and parkinsonism linked to chromosome 17.

13 July 2018

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Antisense-induced exon skipping restores dystrophin expression in DMD patient derived muscle cells

13 July 2018

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Insulin receptor variant forms and type 2 diabetes mellitus

13 July 2018

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Pharmacokinetic properties of 2'-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats

13 July 2018

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Polycystic kidney disease: In danger of being X-rated?

13 July 2018

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13 July 2018

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Restoration of hemoglobin A synthesis in erythroid cells from peripheral blood of thalassemic patients

13 July 2018

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Deletion of individual exons and induction of soluble murine interleukin-5 receptor-alpha chain expression through antisense oligonucleotide-mediated redirection of pre-mRNA splicing.

13 July 2018

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Morpholino antisense oligomers: the case for an RNase H-independent structural type

13 July 2018

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Overexpression of the oncofetal Fn variant containing the EDA splice-in segment in the dermal-epidermal junction of psoriatic uninvolved skin.

13 July 2018

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Correction of aberrant splicing of the cystic fibrosis transmembrane conductance regulator (CFTR) gene by antisense oligonucleotides

13 July 2018

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Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides

13 July 2018

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Aberrant splicing in the PKD2 gene as a cause of polycystic kidney disease

13 July 2018

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Specific removal of the nonsense mutation from the mdx dystrophin mRNA using antisense oligonucleotides.

13 July 2018

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Altered ratios of alternatively spliced long and short gamma2 subunit mRNAs of the gamma-amino butyrate type A receptor in prefrontal cortex of schizophrenics

13 July 2018

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Identification of intron and exon sequences involved in alternative splicing of insulin receptor pre-mRNA.

13 July 2018

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Phosphorothioate oligodeoxyribonucleotides dissociate from cationic lipids before entering the nucleus

13 July 2018

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Enhanced expression of prostate-specific membrane antigen gene in prostate cancer as revealed by in situ hybridization

13 July 2018

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Intracellular distribution and mechanism of delivery of oligonucleotides mediated by cationic lipids

13 July 2018

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13 July 2018

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Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides

13 July 2018

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13 July 2018

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Functional amounts of dystrophin produced by skipping the mutated exon in the mdx dystrophic mouse

13 July 2018

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Molecular genetic profiling of Gleason grade 4/5 prostate cancers compared to benign prostatic hyperplasia

26 September 2018

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Altered gabaa receptor subunit and splice variant expression in rats treated with chronic intermittent ethanol

26 September 2018

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Modification of alternative splicing of Bcl-x pre-mRNA in prostate and breast cancer cells. analysis of apoptosis and cell death.

26 September 2018

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IL-5 and IL-5 receptor in asthma

26 September 2018

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A novel A-->G mutation in intron I of the hepatic lipase gene leads to alternative splicing resulting in enzyme deficiency

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12925686

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Antisense morpholino oligonucleotide analog induces missplicing of C-myc mRNA

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12925686

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI200319547

1 reference

7 August 2017

1 reference

7 August 2017

1 reference