Engineering of RNase P ribozyme for gene-targeting applications (Q35212574)

7 August 2017

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title

Engineering of RNase P ribozyme for gene-targeting applications (English)

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7 August 2017

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Stephen M L Raj

1

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7 August 2017

Fenyong Liu

series ordinal

2

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7 August 2017

language of work or name

English

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publication date

1 August 2003

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7 August 2017

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7 August 2017

volume

313

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7 August 2017

page(s)

59-69

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RNase P in research and therapy

7 August 2017

cites work

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Mutations define essential and nonessential U2 RNA structures.

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Dimeric and monomeric Bacillus subtilis RNase P holoenzyme in the absence and presence of pre-tRNA substrates

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7 January 2021

Tech.Sight. Molecular biology. Making catalytic DNAs.

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7 January 2021

Probing RNA structure and RNA-ligand complexes with chemical probes

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7 January 2021

Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP

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7 January 2021

Comparative photocross-linking analysis of the tertiary structures of Escherichia coli and Bacillus subtilis RNase P RNAs.

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7 January 2021

Evidence for a polynuclear metal ion binding site in the catalytic domain of ribonuclease P RNA.

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7 January 2021

The chemical repertoire of natural ribozymes

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7 January 2021

RNase P-mediated inhibition of cytomegalovirus protease expression and viral DNA encapsidation by oligonucleotide external guide sequences

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7 January 2021

External Guide Sequences for an RNA Enzyme

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7 January 2021

Rational design of self-cleaving pre-tRNA-ribonuclease P RNA conjugates

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7 January 2021

Ribonuclease P: unity and diversity in a tRNA processing ribozyme

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7 January 2021

Expression of small, therapeutic RNAs in human cell nuclei.

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7 January 2021

The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme

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7 January 2021

Phenotypic conversion of drug-resistant bacteria to drug sensitivity

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7 January 2021

Inactivation of gene expression using ribonuclease P and external guide sequences.

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7 January 2021

Further perspective on the catalytic core and secondary structure of ribonuclease P RNA

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7 January 2021

The ribonuclease P family

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7 January 2021

Recombinant AAV-2 harboring gfp-antisense/ribozyme fusion sequences monitor transduction, gene expression, and show anti-HIV-1 efficacy

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7 January 2021

Differential effects of the protein cofactor on the interactions between an RNase P ribozyme and its target mRNA substrate

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7 January 2021

The encapsulation of ribozymes in biodegradable polymeric matrices

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7 January 2021

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RNA structure. Ribozyme evolution at the crossroads

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7 January 2021

Inhibition of viral gene expression by human ribonuclease P.

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7 January 2021

UV cross-link mapping of the substrate-binding site of an RNase P ribozyme to a target mRNA sequence

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7 January 2021

RNase P ribozymes selected in vitro to cleave a viral mRNA effectively inhibit its expression in cell culture

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7 January 2021

Cross-clade inhibition of HIV-1 replication and cytopathology by using RNase P-associated external guide sequences

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7 January 2021

The affinity of magnesium binding sites in the Bacillus subtilis RNase P x pre-tRNA complex is enhanced by the protein subunit

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7 January 2021

Ribozyme-mediated repair of sickle beta-globin mRNAs in erythrocyte precursors

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7 January 2021

mRNA localization signals can enhance the intracellular effectiveness of hammerhead ribozymes

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7 January 2021

Ribozyme gene therapy: applications for molecular medicine

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7 January 2021

Targeted cleavage of mRNA in vitro by RNase P from Escherichia coli

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7 January 2021

Inhibition of viral gene expression by the catalytic RNA subunit of RNase P from Escherichia coli.

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7 January 2021

Requirements for cleavage by a modified RNase P of a small model substrate

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7 January 2021

Intracellular mRNA cleavage induced through activation of RNase P by nuclease-resistant external guide sequences.

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7 January 2021

Derivation of the three-dimensional architecture of bacterial ribonuclease P RNAs from comparative sequence analysis

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7 January 2021

Lentiviral vectors for gene therapy of HIV-1 infection

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7 January 2021

Model substrates for an RNA enzyme

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7 January 2021

Effective inhibition of influenza virus production in cultured cells by external guide sequences and ribonuclease P.

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7 January 2021

G350 of Escherichia coli RNase P RNA contributes to Mg2+ binding near the active site of the enzyme

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7 January 2021

Ribozymes, genomics and therapeutics

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7 January 2021

A general purpose RNA-cleaving DNA enzyme

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7 January 2021

Ribozymes as potential anti-HIV-1 therapeutic agents.

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7 January 2021

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

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7 January 2021

Antisense oligonucleotides as therapeutic agents--is the bullet really magical?

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7 January 2021

Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA.

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7 January 2021

Emerging clinical applications of RNA

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7 January 2021

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7 January 2021

Engineered RNase P ribozymes inhibit gene expression and growth of cytomegalovirus by increasing rate of cleavage and substrate binding.

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7 January 2021

Nuclease footprint analyses of the interactions between RNase P ribozyme and a model mRNA substrate

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https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900677-2

7 January 2021

A ribozyme derived from the catalytic subunit of RNase P from Escherichia coli is highly effective in inhibiting replication of herpes simplex virus 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900677-2

7 January 2021

Effective inhibition of human cytomegalovirus gene expression and replication by a ribozyme derived from the catalytic RNA subunit of RNase P from Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900677-2

7 January 2021

Effective inhibition of herpes simplex virus 1 gene expression and growth by engineered RNase P ribozyme

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900677-2

7 January 2021

Molecular modeling of the three-dimensional structure of the bacterial RNase P holoenzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900677-2

7 January 2021

MODIFIED OLIGONUCLEOTIDES: Synthesis and Strategy for Users

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900677-2

7 January 2021

RNA-protein hybrid ribozymes that efficiently cleave any mRNA independently of the structure of the target RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900677-2

7 January 2021

Eukaryotic ribonuclease P: a plurality of ribonucleoprotein enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900677-2

7 January 2021

A hairpin ribozyme inhibits expression of diverse strains of human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900677-2

7 January 2021

Targeted cleavage of mRNA by human RNase P

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900677-2

7 January 2021

Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide

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https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900677-2

7 January 2021

"Well-determined" regions in RNA secondary structure prediction: analysis of small subunit ribosomal RNA.

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https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900677-2

7 January 2021

10.1016/S0378-1119(03)00677-2

Identifiers

DOI

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release_rxyaunckqbavrjsthj3ksoqe7m

7 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/rxyaunckqbavrjsthj3ksoqe7m

24 November 2022

mapped directly with Wikidata item

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