The first small-molecule inhibitors of members of the ribonuclease E family (Q35548884)

8 August 2017

title

The first small-molecule inhibitors of members of the ribonuclease E family (English)

1 reference

The initiation of mRNA degradation by the direct entry of RNase E and the degradosome with implications for non-nucleolytic gene control

8 August 2017

sponsor

1 reference

Gateway to Research Project ID

Gateway to Research

BB/I001751/1

Erratum: The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family

26 April 2019

corrigendum / erratum

0 references

5

Colin W G Fishwick

1 reference

8 August 2017

Kenneth J McDowall

7

1 reference

8 August 2017

Louise Kime

1

1 reference

8 August 2017

Helen A Vincent

2

1 reference

8 August 2017

Deena M A Gendoo

3

1 reference

8 August 2017

Stefanie S Jourdan

4

1 reference

8 August 2017

Anastasia J Callaghan

6

1 reference

8 August 2017

language of work or name

English

0 references

publication date

26 January 2015

1 reference

full work available at URL

8 August 2017

http://eprints.whiterose.ac.uk/83789/

content deliverer

White Rose Research Online

object of statement has role

published version

copyright license

Creative Commons Attribution 4.0 International

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published in

Scientific Reports

1 reference

8 August 2017

volume

5

1 reference

8 August 2017

page(s)

8028

1 reference

Adjacent single-stranded regions mediate processing of tRNA precursors by RNase E direct entry

8 August 2017

cites work

1 reference

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27 July 2018

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The critical role of RNA processing and degradation in the control of gene expression.

27 July 2018

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27 July 2018

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Rapid cleavage of RNA by RNase E in the absence of 5' monophosphate stimulation

27 July 2018

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Endonucleolytic initiation of mRNA decay in Escherichia coli

27 July 2018

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Rho-independent transcription terminators inhibit RNase P processing of the secG leuU and metT tRNA polycistronic transcripts in Escherichia coli

27 July 2018

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The RNA degradosome of Escherichia coli: an mRNA-degrading machine assembled on RNase E.

27 July 2018

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27 July 2018

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27 July 2018

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Pharmacophore modeling and three dimensional database searching for drug design using catalyst: recent advances

27 July 2018

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Catalytic activation of multimeric RNase E and RNase G by 5'-monophosphorylated RNA

27 July 2018

1 reference

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Quaternary structure and catalytic activity of the Escherichia coli ribonuclease E amino-terminal catalytic domain.

27 July 2018

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Determination of the catalytic parameters of the N-terminal half of Escherichia coli ribonuclease E and the identification of critical functional groups in RNA substrates

27 July 2018

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Hit and lead generation: beyond high-throughput screening

27 July 2018

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RNase G complementation of rne null mutation identifies functional interrelationships with RNase E in Escherichia coli

27 July 2018

1 reference

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Cleavage of poly(A) tails on the 3'-end of RNA by ribonuclease E of Escherichia coli

27 July 2018

1 reference

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Ribonuclease E is a 5'-end-dependent endonuclease

27 July 2018

1 reference

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SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

27 July 2018

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The ams-1 and rne-3071 temperature-sensitive mutations in the ams gene are in close proximity to each other and cause substitutions within a domain that resembles a product of the Escherichia coli mre locus

27 July 2018

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A novel fluorogenic substrate for ribonucleases. Synthesis and enzymatic characterization

27 July 2018

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Structure and functions of ribosomal protein S1.

27 July 2018

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5 S ribosomal RNA is contained within a 25 S ribosomal RNA that accumulates in mutants of Escherichia coli defective in processing of ribosomal RNA

27 July 2018

1 reference

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A conditional lethal mutant of Escherichia coli which affects the processing of ribosomal RNA

27 July 2018

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Gene affecting longevity of messenger RNA: A mutant ofEscherichia coli with altered mRNA stability

27 July 2018

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A conditional lethal mutation in an Escherichia coli strain with a longer chemical lifetime of messenger RNA

27 July 2018

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Direct entry by RNase E is a major pathway for the degradation and processing of RNA in Escherichia coli

27 July 2018

1 reference

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Substrate binding and active site residues in RNases E and G: role of the 5'-sensor

26 September 2018

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The RNase E of Escherichia coli is a membrane-binding protein

26 September 2018

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Sensing of 5' monophosphate by Escherichia coli RNase G can significantly enhance association with RNA and stimulate the decay of functional mRNA transcripts in vivo

26 September 2018

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eHiTS: a new fast, exhaustive flexible ligand docking system

26 September 2018

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The RNA degradosome: life in the fast lane of adaptive molecular evolution

26 September 2018

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Structure of Escherichia coli RNase E catalytic domain and implications for RNA turnover

26 September 2018

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26 September 2018

1 reference

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RNase G (CafA protein) and RNase E are both required for the 5' maturation of 16S ribosomal RNA.

26 September 2018

1 reference

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Site-specific RNase E cleavage of oligonucleotides and inhibition by stem-loops

26 September 2018

1 reference

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Structure of DNase I at 2.0 Å resolution suggests a mechanism for binding to and cutting DNA

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSREP08028

RNase E levels in Escherichia coli are controlled by a complex regulatory system that involves transcription of the rne gene from three promoters

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25619596

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Escherichia coli cafA gene encodes a novel RNase, designated as RNase G, involved in processing of the 5' end of 16S rRNA

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25619596

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

SPROUT: recent developments in the de novo design of molecules

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25619596

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP08028

1 reference

Dimensions Publication ID

8 August 2017

0 references

0 references

1007578724

0 references

Microsoft Academic ID

0 references

1 reference

8 August 2017

1 reference