4-1BB ligand enhances tumor-specific immunity of poxvirus vaccines (Q35781892)

10 August 2017

title

4-1BB ligand enhances tumor-specific immunity of poxvirus vaccines (English)

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10 August 2017

5

Jeffrey Schlom

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10 August 2017

Chie Kudo-Saito

1

1 reference

10 August 2017

James W Hodge

2

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10 August 2017

Heesun Kwak

3

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10 August 2017

Seunghee Kim-Schulze

4

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10 August 2017

Howard L Kaufman

6

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10 August 2017

language of work or name

English

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publication date

31 March 2006

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10 August 2017

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10 August 2017

volume

24

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10 August 2017

issue

23

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10 August 2017

page(s)

4975-4986

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The requirement of multimodal therapy (vaccine, local tumor radiation, and reduction of suppressor cells) to eliminate established tumors

10 August 2017

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Murine CD8 lymphocyte expansion in vitro by artificial antigen-presenting cells expressing CD137L (4-1BBL) is superior to CD28, and CD137L expressed on neuroblastoma expands CD8 tumour-reactive effector cells in vivo

12 July 2018

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Modulation of costimulation to enhance tumor immunity

12 July 2018

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Provision of 4-1BB ligand enhances effector and memory CTL responses generated by immunization with dendritic cells expressing a human tumor-associated antigen

12 July 2018

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Anti-4-1BB monoclonal antibody enhances rejection of large tumor burden by promoting survival but not clonal expansion of tumor-specific CD8+ T cells.

12 July 2018

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4-1BB (CD137) controls the clonal expansion and survival of CD8 T cells in vivo but does not contribute to the development of cytotoxicity

12 July 2018

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4-1BBL enhances anti-tumor responses in the presence or absence of CD28 but CD28 is required for protective immunity against parental tumors.

12 July 2018

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Immunomodulatory gene therapy with interleukin 12 and 4-1BB ligand: long- term remission of liver metastases in a mouse model

12 July 2018

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The envelope protein of an endogenous murine retrovirus is a tumor-associated T-cell antigen for multiple murine tumors

12 July 2018

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12 July 2018

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4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses

12 July 2018

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Transduction and expression of the human carcinoembryonic antigen gene in a murine colon carcinoma cell line

12 July 2018

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12 July 2018

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RMA/S cells present endogenously synthesized cytosolic proteins to class I-restricted cytotoxic T lymphocytes

12 July 2018

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Induction of an antigen cascade by diversified subcutaneous/intratumoral vaccination is associated with antitumor responses

12 July 2018

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Cross-linking of 4-1BB activates TCR-signaling pathways in CD8+ T lymphocytes

25 September 2018

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Immune properties of recombinant vaccinia virus encoding CD154 (CD40L) are determined by expression of virally encoded CD40L and the presence of CD40L protein in viral particles

25 September 2018

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Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance

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Tumor Expression of 4-1BB Ligand Sustains Tumor Lytic T Cells

25 September 2018

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Vaccine therapy of established tumors in the absence of autoimmunity

25 September 2018

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Vaccine-based therapy directed against carcinoembryonic antigen demonstrates antitumor activity on spontaneous intestinal tumors in the absence of autoimmunity.

25 September 2018

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4-1BB promotes the survival of CD8+ T lymphocytes by increasing expression of Bcl-xL and Bfl-1.

25 September 2018

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Divergent effects of 4-1BB antibodies on antitumor immunity and on tumor-reactive T-cell generation.

25 September 2018

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Rejection of disseminated metastases of colon carcinoma by synergism of IL-12 gene therapy and 4-1BB costimulation

25 September 2018

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Vaccinia virus inhibits the maturation of human dendritic cells: a novel mechanism of immune evasion.

25 September 2018

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25 September 2018

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Induction of antitumor immunity by recombinant vaccinia viruses expressing B7-1 or B7-2 costimulatory molecules

25 September 2018

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Antitumor Activity and Immune Responses Induced by a Recombinant Carcinoembryonic Antigen-Vaccinia Virus Vaccine

25 September 2018

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4-1BB co-stimulation enhances human CD8(+) T cell priming by augmenting the proliferation and survival of effector CD8(+) T cells

25 September 2018

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4-1BB ligand induces cell division, sustains survival, and enhances effector function of CD4 and CD8 T cells with similar efficacy

7 January 2021

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Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

7 January 2021

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A novel adenovirus expressing human 4-1BB ligand enhances antitumor immunity

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.042

Costimulation of human CD28- T cells by 4-1BB ligand

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.042

Amplification of tumor immunity by gene transfer of the co-stimulatory 4-1BB ligand: synergy with the CD28 co-stimulatory pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.042

The use of combination vaccinia vaccines and dual-gene vaccinia vaccines to enhance antigen-specific T-cell immunity via T-cell costimulation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.042

Characterization of CD8+ cytotoxic T lymphocyte/tumor cell interactions reflecting recognition of an endogenously expressed murine wild-type p53 determinant

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.042

MHC class I-restricted epitope spreading in the context of tumor rejection following vaccination with a single immunodominant CTL epitope

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VACCINE.2006.03.042

Synergy of vaccine strategies to amplify antigen-specific immune responses and antitumor effects

7 January 2021

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12 December 2020

A triad of costimulatory molecules synergize to amplify T-cell activation

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12 December 2020

Granulocyte/macrophage-colony stimulating factor produced by recombinant avian poxviruses enriches the regional lymph nodes with antigen-presenting cells and acts as an immunoadjuvant

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12 December 2020

Vector-based vaccine/cytokine combination therapy to enhance induction of immune responses to a self-antigen and antitumor activity

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12 December 2020

Mice transgenic for the human carcinoembryonic antigen gene maintain its spatiotemporal expression pattern

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12 December 2020

Costimulation of CD28- T lymphocytes by 4-1BB ligand

1 reference

12 December 2020

10.1016/J.VACCINE.2006.03.042

Identifiers

DOI

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10 August 2017

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10 August 2017

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